The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.
Influence of Delays on Perforation Risk in Adults with Acute Appendicitis
Abstract
PURPOSE: This study analyzed whether prehospital or in-hospital delay was the more significant influence on perforation rates for acute appendicitis and whether any clinical feature designated patients requiring higher surgical priority. METHODS: A retrospective analysis was conducted over one year at a tertiary referral hospital without a dedicated emergency surgical theater. Admission notes, theater logbook, and the Hospital Inpatient Enquiry system were reviewed to identify the characteristics and clinical course of patients aged greater than 16 years who were operated upon for histologically confirmed acute appendicitis. RESULTS: One hundred and fifteen patients were studied. The overall perforation rate was 17 percent. The mean duration of symptoms prior to hospital presentation was 38.1 hours with the mean in-hospital waiting time prior to operation being 23.4 hours. Although body temperature on presentation was significantly greater in patients found to have perforated appendicitis (P < 0.05), only patient heart rate at presentation and overall duration of symptoms, but not in-hospital waiting time, independently predicted perforation by stepwise linear regression modeling. CONCLUSION: In-hospital delay was not an independent predictor of perforation in adults with acute appendicitis although delays may contribute if patients are left to wait unduly. Tachycardia at presentation may be a quantifiable feature of those more likely to have perforation and who should be given higher surgical priority.
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“it has been described that patients presenting to the hospital more than 24hrs after the onset of symptoms are at higher risk of suffering from perforated appendicitis. 9,10”
From Increasing incidence of complicated appendicitis during COVID-19 pandemic (2021) · cites this paper as [10]
Citations
Cites
The Impact of the 80-Hour Resident Workweek on Surgical Residents and Attending Surgeons
Hutter, M. M., Kellogg, K. C., Ferguson, C. M., Abbott, W. M., & Warshaw, A. L. (2006) · Annals of Surgery · doi:10.1097/01.sla.0000220042.48310.66 · Cited by 397
How time affects the risk of rupture in appendicitis
Bickell, N. A., Aufses, A. H., Rojas, M., & Bodian, C. (2006) · Journal of the American College of Surgeons · doi:10.1016/j.jamcollsurg.2005.11.016 · Cited by 370
The Natural History of Appendicitis in Adults A Prospective Study
Temple, C. L. F., Huchcroft, S. A., & TEMPLE, W. J. (1995) · Annals of Surgery · doi:10.1097/00000658-199503000-00010 · Cited by 341
Is It Safe to Delay Appendectomy in Adults With Acute Appendicitis?
Ditillo, M. F., Dziura, J. D., & Rabinovici, R. (2006) · Annals of Surgery · doi:10.1097/01.sla.0000231726.53487.dd · Cited by 305
Mortality After Appendectomy in Sweden, 1987–1996
Blomqvist, P. G., Andersson, R. E., Granath, F. N., Lambe, M. P., & Ekbom, A. (2001) · Annals of Surgery · doi:10.1097/00000658-200104000-00001 · Cited by 245
An Acute Care Surgery Model Improves Outcomes in Patients With Appendicitis
Earley, A. S., Pryor, J. P., Kim, P. K., Hedrick, J. H., Kurichi, J. E., Minogue, A. C., Sonnad, S. S., Reilly, P. M., & Schwab, C. W. (2006) · Transactions of the Meeting of the American Surgical Association · doi:10.1097/01.sla.0000237756.86181.50 · Cited by 223
Delayed versus immediate surgery in acute appendicitis: do we need to operate during the night?
Yardeni, D., Hirschl, R. B., Drongowski, R. A., Teitelbaum, D. H., Geiger, J. D., & Coran, A. G. (2004) · Journal of Pediatric Surgery · doi:10.1016/j.jpedsurg.2003.11.020 · Cited by 221
Effects of Delaying Appendectomy for Acute Appendicitis for 12 to 24 Hours
Abou-Nukta, F. (2006) · Archives of Surgery · doi:10.1001/archsurg.141.5.504 · Cited by 184
Is it necessary to perform appendicectomy in the middle of the night in children?
Surana, R., Quinn, F., & Puri, P. S. (1993) · BMJ · doi:10.1136/bmj.306.6886.1168 · Cited by 121
Delayed appendectomy for appendicitis: Causes and consequences
Titte, S. N. V., McCabe, C. J., & Ottinger, L. W. (1996) · The American Journal of Emergency Medicine · doi:10.1016/s0735-6757(96)90074-1 · Cited by 104
Cited by
Sorted by citations
Time to Appendectomy and Risk of Perforation in Acute Appendicitis
Drake, F. T., Mottey, N. E., Farrokhi, E. T., Florence, M. G., Johnson, M. G., Mock, C., Steele, S. R., Thirlby, R. C., & Flum, D. R. (2014) · JAMA Surgery · doi:10.1001/jamasurg.2014.77 · Cited by 205
van Dijk, S. T., van Dijk, A. H., Dijkgraaf, M. G. W., & Boermeester, M. A. (2018) · British journal of surgery · doi:10.1002/bjs.10873 · Cited by 193
Increasing incidence of complicated appendicitis during COVID-19 pandemic
Orthopoulos, G., Santone, E., Izzo, F., Tirabassi, M., Pérez-Caraballo, A. M., Corriveau, N., & Jabbour, N. (2021) · The American Journal of Surgery · doi:10.1016/j.amjsurg.2020.09.026 · Cited by 171
The Decreasing Incidence of Acute Appendicitis During COVID‐19: A Retrospective Multi‐centre Study
Tankel, J., Keinan, A., Blich, O., Koussa, M., Helou, B., Shay, S., Zugayar, D., Pikarsky, A. J., Mazeh, H., Spira, R. M., et al. (2020) · World Journal of Surgery · doi:10.1007/s00268-020-05599-8 · Cited by 175
Teixeira, P. G., Sivriköz, E., Inaba, K., Talving, P., Lam, L., & Δημητριάδης, Δ. (2012) · Annals of Surgery · doi:10.1097/sla.0b013e318265ea13 · Cited by 168
Metadata
- Authors
- Kearney, D., Cahill, R. A., O'Brien, E., Kirwan, W. O., & Redmond, H. P.
- Affiliations
- Cork University Hospital (IE)
- Venue
- Diseases of the Colon & Rectum
- Published
- 2008-12
- Volume
- 51
- Issue
- 12
- Pages
- 1823-1827
- ISSN
- 0012-3706 (ISSN-L)
- OpenAlex
- W2057072643
- Cited by
- 108
- References
- 20
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 6 · 2023: 9 · 2022: 11 · 2021: 6 · 2020: 4 · 2019: 11 · 2018: 4 · 2017: 6 · 2016: 8 · 2015: 9 · 2014: 4 · 2013: 5 · 2012: 6
- FWCI
- 5.13
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Diseases of the Colon & Rectum (publishedVersion)
- PubMed (publishedVersion)
- Lenus, The Irish Health Repository (Dr Steevens Hospital Library) (submittedVersion)
- Topics
- Health Sciences › Medicine › Emergency Medicine › Appendicitis Diagnosis and Management
- Health Sciences › Medicine › Emergency Medicine › Emergency and Acute Care Studies
- Health Sciences › Medicine › Infectious Diseases › Streptococcal Infections and Treatments
- Keywords
- acute appendicitis, appendiceal perforation, prehospital delay, in-hospital delay, surgical priority, tachycardia, fever, symptom duration, emergency surgery
- MeSH terms
- Adult, Appendectomy, Appendicitis, Emergency Service, Hospital, Female, Humans, Length of Stay, Male, Middle Aged, Retrospective Studies, Risk Factors, Time Factors, Triage, Cohort Studies, Linear Models
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