Efficiency of TachoSil® to prevent postsurgical adhesion development on laparoscopic rat model
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Following standardized injury to the uterine horn, corpus, and peritoneum, TachoSil® application resulted in markedly lower adhesion scores compared to untreated controls: 12.96 vs. 21.66 for the peritoneum, 7.22 vs. 15.20 for the uterine horn, and 5.88 vs. 34.52 for the uterine corpus.
“Following standardized injury to the uterine horn, corpus, and peritoneum, the TachoSil® application resulted in markedly lower adhesion scores compared to untreated controls: 12.96 vs. 21.66 for the peritoneum, 7.22 vs. 15.20 for the uterine horn, and 5.88 vs. 34.52 for the uterine corpus.”
From Biomaterials in Postoperative Adhesion Barriers and Uterine Tissue Engineering (2025) · cites this paper as [67]
In a randomized, controlled laparoscopic rat model, TachoSil® significantly reduced postoperative adhesion formation.
“In a randomized, controlled laparoscopic rat model, TachoSil®, a fibrinogen- and thrombin-coated collagen sponge, significantly reduced postoperative adhesion formation [67].”
From Biomaterials in Postoperative Adhesion Barriers and Uterine Tissue Engineering (2025) · cites this paper as [67]
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Research works printed but not linked: 32
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Biomaterials in Postoperative Adhesion Barriers and Uterine Tissue Engineering
Fazel Anvari-Yazdi, A., Badea, I., & Chen, X. (2025) · Gels · doi:10.3390/gels11060441 · Cited by 20 · see citing works
- Authors
- Nohuz, E., Darcha, C., Moreno, W., Tamburro, S., Yanez, M., Mulliez, A., Grizard, G., Mage, G., & Canis, M.
- Affiliations
- Centre Hospitalier Universitaire de Clermont-Ferrand (FR)
- Corresponding author
- Nohuz, Erdogan
- Venue
- Gynecological Surgery
- Published
- 2009-06-10
- Volume
- 6
- Issue
- 4
- Pages
- 323-329
- ISSN
- 1613-2076 (ISSN-L)
- 1613-2084
- OpenAlex
- W2061787597
- Cited by
- 8
- References
- 0
- Citations by year
- 2025: 1 · 2021: 1 · 2017: 1 · 2016: 1 · 2014: 3
- FWCI
- 0.32
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Gynecological Surgery (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Intestinal and Peritoneal Adhesions
- Health Sciences › Medicine › Hematology › Hemostasis and retained surgical items
- Health Sciences › Medicine › Surgery › Surgical Sutures and Adhesives
- Keywords
- TachoSil, postoperative adhesions, adhesion prevention, laparoscopic surgery, uterine injury, peritoneal injury, bipolar coagulation, uterine fibrosis, inflammation, absorbable biomaterials, rat model
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