Umbrella reviews: what they are and why we need them

Preferred Reporting Items for Systematic Reviews and Meta-Analyses: the PRISMA statement

Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & for the PRISMA Group (2009) · BMJ · doi:10.1136/bmj.b2535 · Cited by 83,823

Bias in meta-analysis detected by a simple, graphical test

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Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement.

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The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration

Liberati, A., Altman, D. G., Tetzlaff, J., Mulrow, C., Gøtzsche, P. C., Ioannidis, J. P. A., Clarke, M., Devereaux, P. J., Kleijnen, J., & Moher, D. (2009) · PLoS Medicine · doi:10.1371/journal.pmed.1000100 · Cited by 28,164

Operating characteristics of a rank correlation test for publication bias

Begg, C. B., & Mazumdar, M. (1994) · Biometrics · doi:10.2307/2533446 · Cited by 16,955

Evidence based medicine: what it is and what it isn't

Sackett, D. L., Rosenberg, W. M. C., Gray, J. A. M., Haynes, R. B., & Richardson, W. S. (1996) · BMJ · doi:10.1136/bmj.312.7023.71 · Cited by 15,769

GRADE guidelines: 1. Introduction—GRADE evidence profiles and summary of findings tables

Guyatt, G., Oxman, A. D., Akl, E. A., Kunz, R., Vist, G., Brozek, J., Norris, S., Falck-Ytter, Y., Glasziou, P., & deBeer, H. (2011) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2010.04.026 · Cited by 10,681

AMSTAR 2: a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both.

Shea, B. J., Reeves, B. C., Wells, G., Thuku, M., Hamel, C., Moran, J., Moher, D., Tugwell, P., Welch, V., Kristjansson, E., et al. (2017) · BMJ · doi:10.1136/bmj.j4008 · Cited by 10,636

GRADE guidelines: 3. Rating the quality of evidence

Balshem, H., Helfand, M., Schünemann, H. J., Oxman, A. D., Kunz, R., Brozek, J., Vist, G. E., Falck-Ytter, Y., Meerpohl, J., & Norris, S. (2011) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2010.07.015 · Cited by 8,285

A basic introduction to fixed-effect and random-effects models for meta-analysis

Borenstein, M., Hedges, L. V., Higgins, J. P. T., & Rothstein, H. R. (2010) · Research Synthesis Methods · doi:10.1002/jrsm.12 · Cited by 6,793

Objectives, design and main findings until 2020 from the Rotterdam Study

Ikram, M. A., Brusselle, G., Ghanbari, M., Goedegebure, A., Ikram, M. K., Kavousi, M., Kieboom, B. C. T., Klaver, C. C. W., de Knegt, R. J., Luik, A. I., et al. (2020) · European Journal of Epidemiology · doi:10.1007/s10654-020-00640-5 · Cited by 463

Association between Adiposity and Cardiovascular Outcomes: An Umbrella Review and Meta-Analysis

Kim, M. S., Kim, W. J., Khera, A. V., Kim, J. Y., Yon, D. K., Lee, S. W., Shin, J. I., & Won, H. (2020) · European Heart Journal · doi:10.1093/eurheartj/ehab454 · Cited by 400

Efficacy of Psychosocial Interventions for Mental Health Outcomes in Low-Income and Middle-Income Countries: An Umbrella Review

Barbui, C., Purgato, M., Abdulmalik, J., Acarturk, C., Eaton, J., Gastaldon, C., Gureje, O., Hanlon, C., Jordans, M., Lund, C., et al. (2020) · The Lancet Psychiatry · doi:10.1016/s2215-0366(19)30511-5 · Cited by 349

Dietary sugar consumption and health: umbrella review

Huang, Y., Chen, Z., Chen, B., Li, J., Yuan, X., Li, J., Wang, W., Dai, T., Chen, H., Wang, Y., et al. (2023) · BMJ · doi:10.1136/bmj-2022-071609 · Cited by 348

Tomato and lycopene and multiple health outcomes: Umbrella review

Li, N., Wu, X., Zhuang, W., Xia, L., Chen, Y., Wu, C., Rao, Z., Du, L., Zhao, R., Yi, M., et al. (2020) · Food Chemistry · doi:10.1016/j.foodchem.2020.128396 · Cited by 267

Pre-existing health conditions and severe COVID-19 outcomes: an umbrella review approach and meta-analysis of global evidence

Treskova, M., Haas, L., Reda, S. A., Pilic, A., Borodova, A., Karimi, K., Koch, J., Nygren, T. M., Scholz, S. M., Schönfeld, V., et al. (2021) · BMC Medicine · doi:10.1186/s12916-021-02058-6 · Cited by 219

Sleep duration and health outcomes: an umbrella review

Li, J. H., Cao, D., Huang, Y. C., Chen, Z., Wang, R., Dong, Q. G., Wei, Q., & Liu, L. (2021) · Sleep And Breathing · doi:10.1007/s11325-021-02458-1 · Cited by 221

Evidence-based umbrella review of 162 peripheral biomarkers for major mental disorders

Carvalho, A. F., Solmi, M., Sanches, M., Machado, M. O., Stubbs, B., Ajnakina, O., Sherman, C., Sun, Y. R., Liu, C. S., Brunoni, A. R., et al. (2020) · Translational Psychiatry · doi:10.1038/s41398-020-0835-5 · Cited by 204

Milk consumption and multiple health outcomes: umbrella review of systematic reviews and meta-analyses in humans

Zhang, X., Chen, X., Xu, Y., Yang, J., Du, L., Li, K., & Zhou, Y. (2021) · Nutrition & Metabolism · doi:10.1186/s12986-020-00527-y · Cited by 195

The Effect of Overdose Education and Naloxone Distribution: An Umbrella Review of Systematic Reviews

Razaghizad, A., Windle, S. B., Filion, K. B., Gore, G. C., Kudrina, I., Paraskevopoulos, E., Kimmelman, J., Martel, M. O., & Eisenberg, M. J. (2021) · American Journal of Public Health · doi:10.2105/ajph.2021.306306 · Cited by 190

Red and processed meat consumption and cancer outcomes: Umbrella review

Huang, Y. C., Cao, D., Chen, Z., Chen, B., Li, J., Guo, J., Dong, Q. G., Liu, L., & Wei, Q. (2021) · Food Chemistry · doi:10.1016/j.foodchem.2021.129697 · Cited by 170

Efficacy of interventions to reduce coercive treatment in mental health services: umbrella review of randomised evidence

Barbui, C., Purgato, M., Abdulmalik, J., Caldas-de-Almeida, J. M., Eaton, J., Gureje, O., Hanlon, C., Nosè, M., Ostuzzi, G., Saraceno, B., et al. (2021) · The British Journal of Psychiatry · doi:10.1192/bjp.2020.144 · Cited by 148

Implementation of Telemental Health Services Before COVID-19: Rapid Umbrella Review of Systematic Reviews

Barnett, P., Goulding, L., Casetta, C., Jordan, H., Sheridan-Rains, L., Steare, T., Williams, J., Wood, L., Gaughran, F., & Johnson, S. (2021) · Journal of Medical Internet Research · doi:10.2196/26492 · Cited by 136

COVID-19 and common mental health symptoms in the early phase of the pandemic: An umbrella review of the evidence

Witteveen, A. B., Young, S. Y., Cuijpers, P. J., Ayuso‐Mateos, J. L., Barbui, C., Bertolini, F., Cabello, M., Cadorin, C., Downes, N., Franzoi, D., et al. (2023) · PLoS Medicine · doi:10.1371/journal.pmed.1004206 · Cited by 151

On the phantom-like appearance of bilingualism effects on neurocognition: (How) should we proceed?

Leivada, E., Westergaard, M. R., Duñabeitia, J. A., & Rothman, J. (2020) · Bilingualism Language and Cognition · doi:10.1017/s1366728920000358 · Cited by 141

Sedentary behavior and cancer–an umbrella review and meta-analysis

Hermelink, R., Leitzmann, M. F., Markozannes, G., Tsilidis, K. K., Pukrop, T., Berger, F. F., Baurecht, H., & Jochem, C. (2022) · European Journal of Epidemiology · doi:10.1007/s10654-022-00873-6 · Cited by 127

Environmental noise exposure and health outcomes: an umbrella review of systematic reviews and meta-analysis

Chen, X., Liu, M., Zuo, L., Wu, X., Chen, M., Li, X., An, T., Chen, L., Xu, W., Peng, S., et al. (2023) · European Journal of Public Health · doi:10.1093/eurpub/ckad044 · Cited by 92

Remote mental health care interventions during the COVID-19 pandemic: An umbrella review

Witteveen, A. B., Young, S. Y., Cuijpers, P. J., Ayuso‐Mateos, J. L., Barbui, C., Bertolini, F., Cabello, M., Cadorin, C., Downes, N., Franzoi, D., et al. (2022) · Behaviour Research and Therapy · doi:10.1016/j.brat.2022.104226 · Cited by 106

Fish consumption and multiple health outcomes: Umbrella review

Li, N., Wu, X., Zhuang, W., Xia, L., Chen, Y., Wu, C., Rao, Z., Du, L., Zhao, R., Yi, M., et al. (2020) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2020.02.033 · Cited by 95

Risk factors for preterm birth: an umbrella review of meta-analyses of observational studies

Mitrogiannis, I., Εvangelou, Ε., Efthymiou, A., Kanavos, T., Birbas, E., Makrydimas, G., & Papatheodorou, S. (2023) · BMC Medicine · doi:10.1186/s12916-023-03171-4 · Cited by 111

Impact of climate events, pollution, and green spaces on mental health: an umbrella review of meta-analyses

Cuijpers, P. J., Miguel, C., Čihařová, M., Kumar, M., Brander, L., Kumar, P., & Karyotaki, E. (2023) · Psychological Medicine · doi:10.1017/s0033291722003890 · Cited by 96

Cheese consumption and multiple health outcomes: an umbrella review and updated meta-analysis of prospective studies

Zhang, M., Dong, X., Huang, Z., Li, X., Zhao, Y., Wang, Y., Zhu, H., Fang, A., & Giovannucci, E. L. (2023) · Advances in Nutrition · doi:10.1016/j.advnut.2023.06.007 · Cited by 87

Nature’s Role in Outdoor Therapies: An Umbrella Review

Harper, N. J., Fernee, C. R., & Gabrielsen, L. E. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18105117 · Cited by 83

Soy and Isoflavone Consumption and Multiple Health Outcomes: Umbrella Review of Systematic Reviews and Meta‐Analyses of Observational Studies and Randomized Trials in Humans

Li, N., Wu, X., Zhuang, W., Xia, L., Chen, Y., Zhao, R., Yi, M., Wan, Q., Du, L., & Zhou, Y. (2019) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201900751 · Cited by 86

The barriers and facilitators for the implementation of clinical practice guidelines in healthcare: an umbrella review of qualitative and quantitative literature

Zhou, P., Chen, L., Wu, Z., Wang, E., Yan, Y., Guan, X., Zhai, S., & Yang, K. (2023) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2023.08.017 · Cited by 79

Umbrella reviews: a methodological guide

Fernandez, R. S., Sharifnia, A. M., & Khalil, H. (2025) · European Journal of Cardiovascular Nursing · doi:10.1093/eurjcn/zvaf012 · Cited by 88

Umbrella reviews (systematic review of reviews)

Faulkner, G., Fagan, M. J., & Lee, J. S. (2021) · International Review of Sport and Exercise Psychology · doi:10.1080/1750984x.2021.1934888 · Cited by 75

Autoimmune diseases and adverse pregnancy outcomes: an umbrella review

Singh, M., Wambua, S., Lee, S. I., Okoth, K., Wang, Z., Fayaz, F. F. A., Eastwood, K.-A., Nelson-Piercy, C., Reynolds, J. A., Nirantharakumar, K., et al. (2024) · BMC Medicine · doi:10.1186/s12916-024-03309-y · Cited by 71

A nine‐step pathway to conduct an umbrella review of literature

Cant, R., Ryan, C. L., & Kelly, M. (2022) · Nurse author & editor · doi:10.1111/nae2.12039 · Cited by 70

Effects of Digital Technologies on Older People’s Access to Health and Social Care: Umbrella Review

Kunonga, P., Spiers, G., Beyer, F. R., Hanratty, B., Boulton, E., Hall, A., Bower, P., Todd, C. J., & Craig, D. (2021) · Journal of Medical Internet Research · doi:10.2196/25887 · Cited by 75

Unsaturated Fatty Acids in Mental Disorders: An Umbrella Review of Meta‐Analyses

Gao, X., Su, X., Han, X., Wen, H., Chen, C., Zhang, S., Li, W., Cai, J., Zheng, L., Ma, J., et al. (2022) · Advances in Nutrition · doi:10.1093/advances/nmac084 · Cited by 71

Associations between constructs related to social relationships and mental health conditions and symptoms: an umbrella review

Pearce, E., Birken, M., Pais, S., Tamworth, M., Ng, Y., Wang, J., Chipp, B., Crane, E., Schlief, M., Yang, J., et al. (2023) · BMC Psychiatry · doi:10.1186/s12888-023-05069-0 · Cited by 88

Concrete Mix Design of Recycled Concrete Aggregate (RCA): Analysis of Review Papers, Characteristics, Research Trends, and Underexplored Topics

Prasittisopin, L., Tuvayanond, W., Kang, T. H. ‐., & Kaewunruen, S. (2025) · Resources · doi:10.3390/resources14020021 · Cited by 73

Non-genetic risk and protective factors and biomarkers for neurological disorders: a meta-umbrella systematic review of umbrella reviews

Mentis, A. A., Dardiotis, E., Efthymiou, V., & Chrousos, G. P. (2021) · BMC Medicine · doi:10.1186/s12916-020-01873-7 · Cited by 85

Vitamin D and Clinical Cancer Outcomes: A Review of Meta‐Analyses

Sluyter, J., Manson, J. E., & Scragg, R. K. R. (2020) · JBMR Plus · doi:10.1002/jbm4.10420 · Cited by 59

Risk factors for hepatocellular carcinoma: an umbrella review of systematic review and meta-analysis

Wang, J., Qiu, K., Zhou, S., Gan, Y., Jiang, K., Wang, D., & Wang, H. (2025) · Annals of Medicine · doi:10.1080/07853890.2025.2455539 · Cited by 59

Non-Pharmacological Nursing Interventions to Prevent Delirium in ICU Patients—An Umbrella Review with Implications for Evidence-Based Practice

Lange, S., Mędrzycka-Dąbrowska, W. A., Friganović, A., Oomen, B., & Krupa, S. (2022) · Journal of Personalized Medicine · doi:10.3390/jpm12050760 · Cited by 76

Vitamin C Intake and Cancers: An Umbrella Review

Chen, Z., Huang, Y. C., Cao, D., Qiu, S., Chen, B., Li, J., Bao, Y., Wei, Q., Han, P., & Liu, L. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2021.812394 · Cited by 61

Associations of sleep with cardiometabolic risk factors and cardiovascular diseases: An umbrella review of observational and mendelian randomization studies

Yang, C., Yan, P., Wu, X., Zhang, W., Cui, H., Zhang, L., Xu, Z., Peng, S., Tang, M., Wang, Y., et al. (2024) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2024.101965 · Cited by 53

Assessing the association between fluoroquinolones and emerging adverse drug reactions raised by regulatory agencies: An umbrella review

Gatti, M., Bianchin, M., Raschi, E., & Ponti, F. D. (2020) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2020.01.009 · Cited by 46

Iron intake and multiple health outcomes: Umbrella review

Huang, Y. C., Cao, D., Chen, Z., Chen, B., Li, J. H., Wang, R., Guo, J., Dong, Q. G., Liu, C., Wei, Q., et al. (2021) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2021.1982861 · Cited by 47

Trends, challenges, and priorities for shared decision making in mental health: The first umbrella review

Chmielowska, M., Zisman‐Ilani, Y., Saunders, R., & Pilling, S. (2023) · International Journal of Social Psychiatry · doi:10.1177/00207640221140291 · Cited by 45

Endocrine disrupting chemicals exposure and health: An umbrella review

Chen, J., Song, P., Li, C., Liu, H., Zhang, L., Zhou, Y., Zhou, Z., & Yan, W. (2025) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2025.118574 · Cited by 46

Outdoor air quality and human health: An overview of reviews of observational studies

Markozannes, G., Pantavou, K., Rizos, E. C., Sindosi, O. Α., Tagkas, C., Seyfried, M., Saldanha, I. J., Hatzianastassiou, N., Nikolopoulos, G. K., & Ntzani, E. (2022) · Environmental Pollution · doi:10.1016/j.envpol.2022.119309 · Cited by 40

Annual Research Review: Mapping the multifaceted approaches and impacts of adverse childhood experiences – an umbrella review of meta‐analyses

Kim, B., & Royle, M. L. (2024) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.14022 · Cited by 41

Validity of observational evidence on putative risk and protective factors: appraisal of 3744 meta-analyses on 57 topics

Janiaud, P., Agarwal, A., Tzoulaki, I., Τheodoratou, E., Tsilidis, K. K., Εvangelou, Ε., & Ioannidis, J. P. A. (2021) · BMC Medicine · doi:10.1186/s12916-021-02020-6 · Cited by 41

Red/processed meat consumption and non-cancer-related outcomes in humans: umbrella review

Zhang, X., Liang, S., Chen, X., Yang, J., Zhou, Y., Du, L., & Li, K. (2022) · British Journal Of Nutrition · doi:10.1017/s0007114522003415 · Cited by 46

From living systematic reviews to meta-analytical research domains

Cuijpers, P. J., Miguel, C., Papola, D., Harrer, M., & Karyotaki, E. (2022) · Evidence-Based Mental Health · doi:10.1136/ebmental-2022-300509 · Cited by 38

Association of tooth loss and nutritional status in adults: an overview of systematic reviews

Kaurani, P., Kakodkar, P. V., Bhowmick, A., Samra, R. K., & Bansal, V. (2024) · BMC Oral Health · doi:10.1186/s12903-024-04602-1 · Cited by 40

The impact of paternal mental illness on child development: an umbrella review of systematic reviews and meta-analyses

Scarlett, H., Moirangthem, S., & van der Waerden, J. E. B. (2023) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-023-02261-1 · Cited by 40

Risk factors for Peri-implantitis: An umbrella review of meta-analyses of observational studies and assessment of biases

Giok, K. C., Veettil, S. K., & Menon, R. K. (2024) · Journal of Dentistry · doi:10.1016/j.jdent.2024.105065 · Cited by 41

A critical reflection on the grading of the certainty of evidence in umbrella reviews

Schlesinger, S., Schwingshackl, L., Neuenschwander, M., & Barbaresko, J. (2019) · European Journal of Epidemiology · doi:10.1007/s10654-019-00531-4 · Cited by 31

Effectiveness of stepped care for mental health disorders: An umbrella review of meta-analyses

Jeitani, A., Fahey, P. P., Gascoigne, M., Darnal, A., & Lim, D. (2024) · Personalized Medicine in Psychiatry · doi:10.1016/j.pmip.2024.100140 · Cited by 30

Diagnostic and prognostic value of echocardiography in pulmonary hypertension: an umbrella review of systematic reviews and meta-analyses

Dong, T.-X., Zhu, Q., Wang, S., Wang, Y.-H., Li, G., Kong, F., & Ma, C. (2023) · BMC Pulmonary Medicine · doi:10.1186/s12890-023-02552-y · Cited by 34

Systematic Reviews in Health Research

Egger, M., Higgins, J. P. T., & Smith, G. D. (2022) · Wiley eBooks · doi:10.1002/9781119099369.ch1 · Cited by 30

What Can We Expect from an Umbrella Review?

Gianfredi, V., Nucci, D., Amerio, A., Signorelli, C., Odone, A., & Dinu, M. (2021) · Advances in Nutrition · doi:10.1093/advances/nmab150 · Cited by 29

Factors influencing the effectiveness of nature-based interventions (NBIs) aimed at improving mental health and wellbeing: An umbrella review

Shrestha, T., Chi, C. V. Y., Cassarino, M., Foley, S., & Blasi, Z. D. (2025) · Environment International · doi:10.1016/j.envint.2024.109217 · Cited by 35

Fruit consumption and multiple health outcomes: An umbrella review

Sun, L., Liang, X., Wang, Y., Zhu, S., Ou, Q., Xu, H., Li, F., Tan, X., Lai, Z., Pu, L., et al. (2021) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2021.09.023 · Cited by 28

Association of bariatric surgery with indicated and unintended outcomes: An umbrella review and meta‐analysis for risk–benefit assessment

Kim, M. S., Kim, J. Y., Song, Y. S., Hong, S., Won, H., Kim, W. J., Kwon, Y., Ha, J., Fiedorowicz, J. G., Solmi, M., et al. (2023) · Obesity Reviews · doi:10.1111/obr.13670 · Cited by 23

Dietary protein and multiple health outcomes: An umbrella review of systematic reviews and meta-analyses of observational studies

Lv, J.-L., Wu, Q., Li, X., Gao, C., Xu, M.-Z., Yang, J., Zang, S., Luan, J., Cai, D.-Z., Chang, Q., et al. (2022) · Clinical Nutrition · doi:10.1016/j.clnu.2022.06.005 · Cited by 24

Effect of exercise-based interventions on stroke rehabilitation: an umbrella review of systematic reviews and meta-analyses

Du, M., Chen, L., Li, Y., Liang, X., Liu, Y., Guo, M., Zhang, Z., Wei, Y. D., & Li, Y. (2025) · Journal of NeuroEngineering and Rehabilitation · doi:10.1186/s12984-025-01781-y · Cited by 31

Effects of nursing interventions to improve inpatients' sleep in intensive and non‐intensive care units: Findings from an umbrella review

Bellon, F., Beti‐Abad, A., Pastells‐Peiró, R., Casado‐Ramírez, E., Moreno‐Casbas, T., Gea‐Sánchez, M., & Abad‐Corpa, E. (2022) · Journal of Clinical Nursing · doi:10.1111/jocn.16251 · Cited by 30

NextGEM: Next-Generation Integrated Sensing and Analytical System for Monitoring and Assessing Radiofrequency Electromagnetic Field Exposure and Health

Petroulakis, N. E., Mattsson, M., Chatziadam, P., Simkó, M., Gavrielides, A., Yiorkas, A. M., Zeni, O., Scarfı̀, M. R., Soudah, E., Otin, R., et al. (2023) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph20126085 · Cited by 20

Effectiveness and Safety of COVID-19 Vaccinations: An Umbrella Meta-Analysis

Jiesisibieke, Z. L., Liu, W., Yang, Y., Chien, C.-W., & Tung, T. (2023) · International Journal of Public Health · doi:10.3389/ijph.2023.1605526 · Cited by 21

The role of diet and nutrition related indicators in biliary diseases: an umbrella review of systematic review and meta-analysis

Wang, Y., Lu, J., Wen, N., Nie, G., Peng, D., Xiong, X., Cheng, N., & Li, B. (2022) · Nutrition & Metabolism · doi:10.1186/s12986-022-00677-1 · Cited by 20

Review of systematic reviews in educational leadership and management: Methods used, topics explored and geographies covered

Mertkan, Ş., & Gümüş, S. (2024) · Educational Management Administration & Leadership · doi:10.1177/17411432241291197 · Cited by 21

Does dental trauma have impact on the oral health-related quality of life of children and adolescents?

Tewari, N., Mathur, V. P., Goel, S., Rahul, M., Srivastav, S., Sultan, F., Haldar, P., & Ritwik, P. (2023) · Evidence-Based Dentistry · doi:10.1038/s41432-023-00849-9 · Cited by 19

A Primer on Systematic Review and Meta-analysis in Diabetes Research

Tobias, D. K., Papatheodorou, S., Yamamoto, J. M., & Hu, F. B. (2023) · Diabetes Care · doi:10.2337/dci23-0031 · Cited by 19

The relationship between nonsteroidal anti-inflammatory drugs and cancer incidence: An umbrella review

Wang, P., Chen, B., Huang, Y. C., Li, J., Cao, D., Chen, Z., Li, J., Ran, B., Yang, J., Wang, R., et al. (2024) · Heliyon · doi:10.1016/j.heliyon.2023.e23203 · Cited by 21

ABO and Rhesus blood groups and multiple health outcomes: an umbrella review of systematic reviews with meta-analyses of observational studies

Liu, F.-H., Guo, J.-K., Xing, W.-Y., Bai, X., Chang, Y.-J., Zhao, L., Yang, M., Yang, Y., Li, W., Jia, X., et al. (2024) · BMC Medicine · doi:10.1186/s12916-024-03423-x · Cited by 18

The State of Evidence in Digital Hate Research: An Umbrella Review

Matthes, J., Koban, K., Bührer, S., Kirchmair, T., Weiß, P., Khaleghipour, M., Saumer, M., & Meerson, R. (2025) · Communication Research · doi:10.1177/00936502251365724 · Cited by 19

Air pollution as cause of mental disease: Appraisal of the evidence

Ioannidis, J. P. A. (2019) · PLoS Biology · doi:10.1371/journal.pbio.3000370 · Cited by 18

Teledentistry for improving access to, and quality of oral health care: A protocol for an overview of systematic reviews and meta-analyses

Talla, P. K., Allison, P. J., Bussières, A., Giraudeau, N., Komarova, S. V., Basiren, Q., Bergeron, F., & Emami, E. (2024) · PLoS ONE · doi:10.1371/journal.pone.0288677 · Cited by 21

Effects of probiotics, prebiotics and synbiotics on anthropometric, cardiometabolic and inflammatory markers: An umbrella review of meta-analyses

Teo, Y. Q. J., Chong, B., Soong, R. Y., Yong, C. L., Chew, N., & Chew, H. S. J. (2024) · Clinical Nutrition · doi:10.1016/j.clnu.2024.05.019 · Cited by 23

Effects of pharmacist interventions on cardiovascular risk factors and outcomes: An umbrella review of meta‐analysis of randomized controlled trials

Rattanavipanon, W., Chaiyasothi, T., Puchsaka, P., Mungkornkaew, R., Nathisuwan, S., Veettil, S. K., & Chaiyakunapruk, N. (2022) · British Journal of Clinical Pharmacology · doi:10.1111/bcp.15279 · Cited by 27

Diagnostic accuracy of interleukin-6 in multiple diseases: An umbrella review of meta-analyses

Han, Z., Li, J., Yi, X., Zhang, T., Liao, D., You, J. E., & Ai, J. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e27769 · Cited by 21

Interventions for psychiatric disorders among university students: An umbrella review of systematic reviews and meta-analyses

Huang, H., Huang, S., Chen, S., Gao, X., Cai, J., Feng, Y., Liu, J., Su, X., Qiu, J., Zhang, S., et al. (2024) · International Journal of Clinical and Health Psychology · doi:10.1016/j.ijchp.2023.100431 · Cited by 22

Environmental pollutant exposure and adverse neurodevelopmental outcomes: An umbrella review and evidence grading of meta-analyses

Gao, X., Zheng, X., Wang, X., Li, Z., & Yang, L. (2025) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2025.137832 · Cited by 16

Types and associated methodologies of overviews of reviews in health care: a methodological study with published examples

Bougioukas, K. I., Pamporis, K., Vounzoulaki, E., Karagiannis, T., & Haidich, A. (2022) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2022.11.003 · Cited by 15

The Benefits of Hearing Aids for Adults: A Systematic Umbrella Review

Tang, D., Tran, Y., Bennett, R. J., Lo, C., Lee, J. N., Turner, J., & Gopinath, B. (2025) · Ear and Hearing · doi:10.1097/aud.0000000000001620 · Cited by 14

Efficacy of preventive interventions against ventilator-associated pneumonia in critically ill patients: an umbrella review of meta-analyses

Zhu, D., Zhao, Q., Guo, S., Bai, L., Yang, S., Zhao, Y., Xu, Y., & Zhou, X. (2024) · Journal of Hospital Infection · doi:10.1016/j.jhin.2023.12.017 · Cited by 16

Umbrella review of photodynamic therapy for cancer: efficacy, safety, and clinical applications

Chen, H., Li, H., Li, H., & Zhang, Z. (2025) · Frontiers in Oncology · doi:10.3389/fonc.2025.1528314 · Cited by 13

Effects of Posterior Tibial Nerve Stimulation on Fecal Incontinence: An Umbrella Review

Tahmasbi, F., Mosaddeghi-Heris, R., Soleimanzadeh, F., Ghaderpanah, R., Sadrian, S. H., Hajebrahimi, S., & Salehi‐Pourmehr, H. (2023) · Neuromodulation Technology at the Neural Interface · doi:10.1016/j.neurom.2023.06.004 · Cited by 13

Evidence linking COVID-19 and the health/well-being of children and adolescents: an umbrella review

Duan, C., Liu, L., Wang, T., Wang, G., Jiang, Z., Li, H., Zhang, G., Li, Y., Li, C., & Cao, Y. (2024) · BMC Medicine · doi:10.1186/s12916-024-03334-x · Cited by 16

Probiotics/prebiotics/synbiotics and human neuropsychiatric outcomes: an umbrella review

Du, Q., Li, Q., Liu, C., Liao, G., Li, J., Yang, J., Zhang, Q., Gong, X., & Li, K. (2017) · Beneficial Microbes · doi:10.1163/18762891-bja00035 · Cited by 13

Workplace violence and harassment: An umbrella review of synthesis studies

Kim, B. (2024) · Aggression and Violent Behavior · doi:10.1016/j.avb.2024.101981 · Cited by 10

An overview of applications and trends of STEM for learning effectiveness——An umbrella review based on 22 meta-analyses

Lu, J., Si, H., Xu, J., & Xu, T.-G. (2025) · Educational Research Review · doi:10.1016/j.edurev.2025.100712 · Cited by 10

An Umbrella Review and a Meta-analysis of Metaanalyses of Disordered Eating Among Medical Students

Jahrami, H., Saif, Z., Trabelsi, K., Ghazzawi, H., Pandi-Perumal, S. R., & Seeman, M. V. (2024) · ALPHA PSYCHIATRY · doi:10.5152/alphapsychiatry.2024.241515 · Cited by 13

Factors influencing the effectiveness of nature-based interventions (NBIs) aimed at improving mental health and wellbeing: Protocol of an umbrella review

Shrestha, T., Chi, C. V. Y., Cassarino, M., Foley, S., & Blasi, Z. D. (2023) · PLoS ONE · doi:10.1371/journal.pone.0273139 · Cited by 13

The Effectiveness of Acupuncture for Low Back Pain: An Umbrella Review and Meta-Analysis

Wu, M., Fan, C., Liu, H., Chen, X., Zhen, G., Zhao, X., Zhou, J., & Jiang, Z. (2024) · The American Journal of Chinese Medicine · doi:10.1142/s0192415x2450037x · Cited by 10

Umbrella Review on the Relationship between Vitamin D Levels and Cancer

Schömann-Finck, M., & Reichrath, J. (2024) · Nutrients · doi:10.3390/nu16162720 · Cited by 9

Association between obstructive sleep apnea and multiple adverse clinical outcomes: evidence from an umbrella review

Wang, Q., Zeng, H., Dai, J., Zhang, M., & Shen, P. (2025) · Frontiers in Medicine · doi:10.3389/fmed.2025.1497703 · Cited by 9

Generative AI in practice: An umbrella review of risks, benefits, ethics, and future directions across major domains

Hodzic, S., Stević, A., & Matthes, J. (2026) · Technology in Society · doi:10.1016/j.techsoc.2026.103331 · Cited by 9

Human papillomavirus infection and non-oropharyngeal head and neck cancers: an umbrella review of meta-analysis

Petrelli, F., Cin, E. D., Ghidini, A., Carioli, D., Falasca, V., Stefani, A. D., Moleri, G., Ardito, R., Luciani, A., Nardone, M., et al. (2023) · European Archives of Oto-Rhino-Laryngology · doi:10.1007/s00405-023-08027-4 · Cited by 9

Generative artificial intelligence in education: an umbrella review of applications and challengesPreprint

Namoun, A., Ibrahim, I. A., Mustafa, E., Alrehaili, A., Tufail, A., Shuja, J., & Bilal, K. (2024) · Research Square · doi:10.21203/rs.3.rs-4892155/v1 · Cited by 11

Revisiting the association between pretreatment thrombocytosis and cancer survival outcomes: an umbrella review of meta-analyses

Shu, C., Wang, X., Li, C., Huang, J., Xie, X., Li, H., Zhao, J., Wang, Z., He, Y., & Zhou, Y. (2024) · BMC Cancer · doi:10.1186/s12885-024-13027-6 · Cited by 10

The impact of the management strategies for patients with subclinical hypothyroidism on long-term clinical outcomes: An umbrella review

Bauer, B. S., Azcoaga-Lorenzo, A., Agrawal, U., Fagbamigbe, A. F., & McCowan, C. (2022) · PLoS ONE · doi:10.1371/journal.pone.0268070 · Cited by 12

Strategies for knowledge exchange for action to address place-based determinants of health inequalities: an umbrella review

Halliday, E. C., Tompson, A., McGill, E., Egan, M., & Popay, J. (2022) · Journal of Public Health · doi:10.1093/pubmed/fdac146 · Cited by 8

Chemotherapy and targeted therapy for advanced biliary tract cancers: an umbrella review

Wang, Y., Wen, N., Wang, S., Nie, G., Tian, Y., Lu, J., & Li, B. (2023) · BMC Cancer · doi:10.1186/s12885-023-10679-8 · Cited by 8

Addressing the commercial determinants of mental health: an umbrella review of population-level interventions

Tompson, A., Alkasaby, M. A., Choudhury, T., Dun-Campbell, K., Hartwell, G., Körner, K., Maani, N., van Schalkwyk, M. C., & Petticrew, M. P. (2024) · Health Promotion International · doi:10.1093/heapro/daae147 · Cited by 8

A critical reflection on the grading of the certainty of evidence in umbrella reviews

Schlesinger, S., Schwingshackl, L., Neuenschwander, M., & Barbaresko, J. (2019) · European Journal of Epidemiology · doi:10.1007/s10654-019-00531-4 · Cited by 31

Author Reply: A critical reflection on the grading of the certainty of evidence in umbrella reviews

Papatheodorou, S. (2019) · European Journal of Epidemiology · doi:10.1007/s10654-019-00535-0 · Cited by 1

Umbrellas Dangerous.

(1869) · PubMed Central

Building a better umbrella.

Styles, M. M. (1987) · PubMed

An umbrella--or a crutch.

Lux, B. (1969) · PubMed