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Cited by 58Pharmaceutical and Antibiotic Environmental ImpactsEnvironmental Chemistry and AnalysisMicrobial bioremediation and biosurfactants

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Microbial degradation of antibiotic: future possibility of mitigating antibiotic pollution

Kayal, Aindrila, Mandal, Sukhendu·2022·Environmental Monitoring and Assessment
DOI 10.1007/s10661-022-10314-2
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Abstract

Antibiotics are the major pharmaceutical wastes that are being exposed to the environment from the pharmaceutical industries and for the anthropogenic activities. The use of antibiotics for disease prevention and treatment in humans has been surpassed by the amount used in agriculture, particularly on livestock. It is stipulated that the overuse of antibiotics is the single largest reason behind the rise of bacterial anti-microbial resistance (AMR). The development of alternative therapy, like gene therapy, immunotherapy, use of natural products, and various nanoparticles, to control bacterial pathogens might be an alternative of antibiotics for mankind but the remediation of already exposed antibiotics from the lithosphere and hydrosphere needs to be envisioned with priority. The ever-increasing release of antibiotics in the environment makes it one of the major emerging contaminants (ECs). Decomposition of such antibiotic contaminants is a great challenge to get a cleaner environment. There are reports describing the degradation of antibiotics by photolysis, hydrolysis, using cathode and metal salts, or by degradation via microbes. Antimicrobials like sulfonamides are recalcitrant to natural biodegradation, exhibiting high thermal stability. There are recent reports on microbial degradation of a few common antibiotics and their derivatives but their applications in waste management are scanty. It could however be a major concern to the scientists whether to use the antibiot…

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Metadata

Authors
Kayal, A., & Mandal, S.
Affiliations
University of Calcutta (IN)
Corresponding author
Mandal, Sukhendu
ORCID
Mandal, Sukhendu
Venue
Environmental Monitoring and Assessment
Publisher
Springer Science and Business Media LLC
Published
2022-08-04
Volume
194
Issue
9
Pages
639-639
ISSN
  • 0167-6369 (ISSN-L)
  • 1573-2959
DOI
10.1007/s10661-022-10314-2
OpenAlex
W4289793202
Cited by
58
References
1
Citations by year
2026: 19 · 2025: 20 · 2024: 9 · 2023: 10
FWCI
0.55
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • Environmental Monitoring and Assessment (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Physical Sciences › Environmental Science › Pollution › Pharmaceutical and Antibiotic Environmental Impacts
  • Physical Sciences › Environmental Science › Environmental Chemistry › Environmental Chemistry and Analysis
  • Physical Sciences › Environmental Science › Pollution › Microbial bioremediation and biosurfactants
Keywords
antibiotic pollution, microbial degradation, antibiotic biodegradation, antimicrobial resistance, emerging contaminants, pharmaceutical waste, sulfonamides, horizontal gene transfer, antibiotic resistance genes, bioremediation, antibiotic use in livestock, antibiotic alternatives
MeSH terms
Anti-Bacterial Agents, Bacteria, Bacterial Infections, Biodegradation, Environmental, Environmental Monitoring, Humans

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