A Case–Control Study of Personality Style and Psychopathology in Parents of Subjects with Autism
Abstract
To probe the specificity of traits that might be conceptualised as the broader phenotype of autism, parents of subjects with autism from simplex and multiplex families as well as parents of subjects with obsessive-compulsive disorders (OCD), early onset schizophrenia (EOS) and mental retardation (MR) were assessed using the Personality Style and Disorder Inventory and the Symptom Checklist-90-Revised. Autism parents' scores were increased on several subscales (e.g. reserved/schizoid, depression) compared to parents of subjects with OCD, EOS and normative data, but not in comparison to MR parents. Results provide some support for the specificity of the broader phenotype of autism. The burden of raising severely disabled children could not be ruled out as a factor influencing parts of this phenotype.
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ASD is both a clinically relevant phenomenon and a quantitative trait in the general population, with broader subclinical phenotypes frequently present in relatives.
“It is both a clinically relevant phenomenon, and a quantitative trait in the general population, with broader subclinical phenotypes frequently present in relatives [247, 248].”
From The contribution of environmental exposure to the etiology of autism spectrum disorder (2019) · cites this paper as [248]
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References 46 · Cited by 42
- Authors
- Bölte, S., Knecht, S., & Poustka, F.
- Affiliations
- Goethe University Frankfurt (DE)
- Universität Ulm (DE)
- Corresponding author
- Bölte, Sven
- ORCID
- Bölte, Sven
- Venue
- Journal of Autism and Developmental Disorders
- Published
- 2006-08-08
- Volume
- 37
- Issue
- 2
- Pages
- 243-250
- ISSN
- 0162-3257 (ISSN-L)
- 1573-3432
- OpenAlex
- W1973644070
- Cited by
- 42
- References
- 46
- Citations by year
- 2023: 1 · 2022: 3 · 2021: 3 · 2020: 4 · 2018: 1 · 2017: 4 · 2016: 1 · 2015: 4 · 2014: 5 · 2013: 2 · 2012: 1
- FWCI
- 1.30
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Journal of Autism and Developmental Disorders (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Social Sciences › Psychology › Clinical Psychology › Family and Disability Support Research
- Social Sciences › Psychology › Clinical Psychology › Personality Traits and Psychology
- Keywords
- autism spectrum disorder, parental personality, broader autism phenotype, multiplex families, simplex families, obsessive-compulsive disorder, early-onset schizophrenia, intellectual disability, parental depression, schizoid traits, caregiver burden, psychopathology
- MeSH terms
- Adult, Autistic Disorder, Child, Female, Humans, Male, Intellectual Disability, Obsessive-Compulsive Disorder, Parents, Personality Disorders, Personality Inventory, Severity of Illness Index, Child of Impaired Parents
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