Psychotropic Medication Use Among Children With Autism Spectrum Disorders Enrolled in a National Registry, 2007–2008
Abstract
Patterns of current psychotropic medication use among 5,181 children with autism spectrum disorders (ASD) enrolled in a Web-based registry were examined. Overall, 35% used at least one psychotropic medication, most commonly stimulants, neuroleptics, and/or antidepressants. Those who were uninsured or exclusively privately insured were less likely to use >or=3 medications than were those insured by Medicaid. Psychiatrists and neurologists prescribed the majority of psychotropic medications. In multivariate analysis, older age, presence of intellectual disability or psychiatric comorbidity, and residing in a poorer county or in the South or Midwest regions of the United States increased the odds of psychotropic medication use. Factors external to clinical presentation likely affect odds of psychotropic medication use among children with ASD.
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The estimate of polypharmacy in this study is higher than reports from prior longitudinal studies in solely pediatric populations with ASD.
“This estimate is higher than reports from prior longitudinal studies in solely pediatric populations with ASD.”
From Medication use in the management of comorbidities among individuals with autism spectrum disorder from a large nationwide insurance database (2021) · cites this paper as [37]
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References 38 · Cited by 154
- Authors
- Rosenberg, R. E., Mandell, D. S., Farmer, J. E., Law, J. K., Marvin, A. R., & Law, P. A.
- Affiliations
- Kennedy Krieger Institute (US)
- University of Pennsylvania (US)
- University of Missouri (US)
- Corresponding author
- Law, Paul A.
- Venue
- Journal of Autism and Developmental Disorders
- Published
- 2009-10-06
- Volume
- 40
- Issue
- 3
- Pages
- 342-351
- ISSN
- 0162-3257 (ISSN-L)
- 1573-3432
- OpenAlex
- W2085001620
- Cited by
- 154
- References
- 38
- Citations by year
- 2026: 2 · 2025: 5 · 2024: 8 · 2023: 7 · 2022: 6 · 2021: 6 · 2020: 10 · 2019: 6 · 2018: 10 · 2017: 13 · 2016: 11 · 2015: 11 · 2014: 15 · 2013: 20 · 2012: 15
- FWCI
- 3.86
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Journal of Autism and Developmental Disorders (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Autism Speaks
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
- Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
- Keywords
- psychotropic drug use, autism spectrum disorder, children, stimulants, antipsychotic drugs, antidepressants, Medicaid, insurance status, intellectual disability, psychiatric comorbidity, prescribing patterns, regional disparities, socioeconomic factors
- MeSH terms
- Adolescent, Central Nervous System Stimulants, Antidepressive Agents, Autistic Disorder, Child, Child, Preschool, Drug Utilization, Female, Humans, Infant, Male, Psychotropic Drugs, Surveys and Questionnaires, Registries, Retrospective Studies, Socioeconomic Factors, Antipsychotic Agents, United States, Multivariate Analysis, Treatment Outcome, Risk Assessment, Prescription Drugs
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