Are autism spectrum conditions more prevalent in an information-technology region? A school-based study of three regions in the Netherlands
Open accessAbstract
We tested for differences in the prevalence of autism spectrum conditions (ASC) in school-aged children in three geographical regions in the Netherlands. Schools were asked to provide the number of children enrolled, the number having a clinical diagnosis of ASC and/or two control neurodevelopmental conditions. Prevalence was evaluated by negative binomial regression and adjustments were made for non-response and size of the schools. The prevalence estimates of ASC in Eindhoven was 229 per 10,000, significantly higher than in Haarlem (84 per 10,000) and Utrecht (57 per 10,000), whilst the prevalence for the control conditions were similar in all regions. Phase two is planned to validate school-reported cases using standardized diagnostic methods and to explore the possible causes for these differences.
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References 35 · Cited by 101
- Authors
- Roelfsema, M. T., Hoekstra, R. A., Allison, C., Wheelwright, S., Brayne, C., Matthews, F. E., & Baron-Cohen, S.
- Affiliations
- University of Cambridge (GB)
- The Open University (GB)
- MRC Biostatistics Unit (GB)
- Venue
- Journal of Autism and Developmental Disorders
- Published
- 2011-06-17
- Volume
- 42
- Issue
- 5
- Pages
- 734-739
- ISSN
- 0162-3257 (ISSN-L)
- 1573-3432
- OpenAlex
- W2063102732
- Cited by
- 101
- References
- 35
- Citations by year
- 2026: 4 · 2025: 4 · 2024: 3 · 2023: 6 · 2022: 5 · 2021: 10 · 2020: 10 · 2019: 7 · 2018: 6 · 2017: 10 · 2016: 5 · 2015: 12 · 2014: 2 · 2013: 9 · 2012: 7
- FWCI
- 3.08
- Type
- journal article
- Language
- en
- Open access
- Licence
- Locations
- Journal of Autism and Developmental Disorders (publishedVersion)
- PubMed (publishedVersion)
- Open Research Online (The Open University) (acceptedVersion)
- Repository@Hull (Worktribe) (University of Hull) (submittedVersion, cc-by)
- Repository@Hull (Worktribe) (University of Hull) (submittedVersion)
- Research Portal (King's College London) (submittedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Social Sciences › Psychology › Clinical Psychology › Family and Disability Support Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
- Keywords
- autism spectrum disorder, prevalence, regional variation, school-aged children, neurodevelopmental disorders, Eindhoven, Haarlem, Utrecht, student enrollment statistics
- MeSH terms
- Adolescent, Child, Child Development Disorders, Pervasive, Female, Humans, Male, Netherlands, Surveys and Questionnaires, Schools, Sex Factors, Prevalence
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