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Cited by 18Assisted Reproductive Technology and Twin PregnancyReproductive Health and TechnologiesReproductive Biology and Fertility

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Morbid obesity and pregnancy outcomes after single blastocyst transfer: a retrospective, North American study

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Russo, Miguel, Ates, Senem, Shaulov, Talya, Dahan, Michael H.·2017·Journal of Assisted Reproduction and Genetics
DOI 10.1007/s10815-017-0883-9PMC PMC5401700
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Abstract

Purpose Maternal obesity has been shown to affect reproductive function and pregnancy outcomes following in vitro fertilization. More recently, studies have demonstrated lower live birth rates after single blastocyst transfer (SBT) in patients who are overweight or obese. However, the impact of morbid obesity on pregnancy outcomes after SBT has not been well elucidated. The present study aimed to determine whether morbid obesity has a detrimental impact on pregnancy outcomes after SBT in a North American population. Methods A retrospective, cohort study including 520 nulliparous and multiparous women undergoing top-quality SBT between August 2010 and March 2014 at a University Health Centre in North America was conducted. Primary outcomes included: miscarriage rate, clinical pregnancy rate, and live birth rate. Subjects were divided into different BMI categories (kg/m 2), including <20, 20-24.9, 25.0-29.9, 30-40, and 40 or more. Results The miscarriage rate per pregnancy for each group, respectively, was 36, 64, 59, 61, and 50% (p = 0.16); the clinical pregnancy (per patient) rate per group was 36, 52, 38, 26, and 10% (p = 0.009); and the live birth rate (per patient) per group was 35, 50, 38, 26 and 10% (p = 0.03). Conclusion Morbid obesity is a strong and independent predictor of poor pregnancy outcomes in patients undergoing top-quality SBT.

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Research works printed but not linked: 24

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Cited by

Metadata

Authors
Russo, M., Ates, S., Shaulov, T., & Dahan, M. H.
Affiliations
  • University of Ottawa (CA)
  • McGill University Health Centre (CA)
Corresponding author
Russo, Miguel
ORCID
Venue
Journal of Assisted Reproduction and Genetics
Publisher
Springer Science and Business Media LLC
Published
2017-02-11
Volume
34
Issue
4
Pages
451-457
ISSN
  • 0740-7769 (ISSN-L)
  • 1058-0468
  • 1573-7330
DOI
10.1007/s10815-017-0883-9
PMC
PMC5401700
OpenAlex
W2587347823
Cited by
18
References
0
Citations by year
2026: 2 · 2025: 1 · 2023: 1 · 2022: 2 · 2021: 4 · 2020: 3 · 2019: 1 · 2018: 3 · 2017: 1
FWCI
2.39
Type
journal article
Language
en
Open access
Licence
www.springer.com/tdm (unspecified)
Locations
  • Journal of Assisted Reproduction and Genetics (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Assisted Reproductive Technology and Twin Pregnancy
  • Health Sciences › Medicine › Reproductive Medicine › Reproductive Health and Technologies
  • Health Sciences › Medicine › Reproductive Medicine › Reproductive Biology and Fertility
Keywords
morbid obesity, maternal obesity, single blastocyst transfer, pregnancy outcomes, miscarriage rate, clinical pregnancy rate, live birth rate, body mass index, in vitro fertilization, nulliparous women, multiparous women
MeSH terms
Abortion, Spontaneous, Adult, Blastocyst, Embryo Transfer, Female, Fertilization in Vitro, Humans, North America, Obesity, Morbid, Pregnancy, Pregnancy Outcome, United States

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