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Cited by 12Reproductive Biology and FertilitySperm and Testicular FunctionReproductive biology and impacts on aquatic species

Long-term storage of gametes and gonadal tissues at room temperatures: The end of the ice age?

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Comizzoli, Pierre, Loi, Pasqualino, Patrizio, Pasquale, Hubel, Allison·2022·Journal of Assisted Reproduction and Genetics
DOI 10.1007/s10815-021-02392-xPMC PMC8956754
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Abstract

Long-term preservation of viable spermatozoa, eggs, embryos, and gonadal tissues of good quality is essential in human reproductive medicine and for the population management of livestock, laboratory, and wild species. Instead of using freezing temperatures, encouraging findings indicate that structures and functions of gametes or gonadal tissues can be suspended in trehalose glass after dehydration and then preserved at supra-zero temperatures. As a new era in fertility preservation and biobanking is about to start, the advantages, needs, and implications of germplasm storage at room temperatures must be carefully examined. Although very promising, the development of alternate biobanking strategies does not necessarily mean that the end of the "ice age" (cryopreservation) is near.

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Cited by

Sorted by citations

Authors
Comizzoli, P., Loi, P., Patrizio, P., & Hubel, A.
Affiliations
  • Smithsonian Conservation Biology Institute (US)
  • University of Teramo (IT)
  • University of Miami (US)
  • University of Minnesota (US)
Corresponding author
Comizzoli, Pierre
ORCID
Venue
Journal of Assisted Reproduction and Genetics
Publisher
Springer Science and Business Media LLC
Published
2022-01-04
Volume
39
Issue
2
Pages
321-325
ISSN
  • 0740-7769 (ISSN-L)
  • 1058-0468
  • 1573-7330
DOI
10.1007/s10815-021-02392-x
PMC
PMC8956754
OpenAlex
W4206568342
Cited by
12
References
0
Citations by year
2026: 2 · 2024: 2 · 2023: 1 · 2022: 6
FWCI
1.90
Type
journal article
Language
en
Open access
Licence
Locations
  • Journal of Assisted Reproduction and Genetics (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • Zenodo (CERN European Organization for Nuclear Research) (submittedVersion, cc-by)
  • UniTERAMO Research Catalog (University of Teramo) (submittedVersion)
  • Zenodo (CERN European Organization for Nuclear Research) (cc-by)
Funders
National Institutes of Health (R01OD023139)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Reproductive Biology and Fertility
  • Health Sciences › Medicine › Reproductive Medicine › Sperm and Testicular Function
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Physiology › Reproductive biology and impacts on aquatic species
Keywords
gamete preservation, spermatozoa, eggs, embryo, fertility preservation
MeSH terms
Germ Cells, Humans, Male, Spermatozoa, Temperature, Cryopreservation, Biological Specimen Banks, Fertility Preservation

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