Recent trends on biomaterials for tissue regeneration applications: Review
Open accessAbstract
Tissue engineering is approach of replacing or regeneration of biological functions of tissues or organs by using combination of biomaterials, biomolecules and cells. Tissue engineering mainly depends scaffold biomaterials and scaffold fabrication methods. Therefore, there have been progressive investigation and development of new biomaterials with different formulations to help and achieve necessary requirements in the tissue engineering applications. This review is briefly representing necessary features associated with biomaterial type and design required for tissue regeneration applications, and presenting earlier research in tissue engineering field and new trends for future implementation. It is mainly focusing on generations of biomaterials and discovery tissue engineering field. As well as, different types of biomaterials, such as bioceramics, bioactive glasses, synthetic and natural polymers and their derived composites, used in fabrication of scaffolds (as a main part of tissue engineering) are demonstrated in this review. Scaffold fabrication methods are also reviewed here. Moreover, it is showing the recent achievements in tissue engineering field for bone, skin, cartilage, neural, and cardiac regeneration as a pre-clinical procedure for repair of injured and diseased tissues and organs. Finally, recent trends and challenges of biomaterials for tissue regeneration are presented also in this review. Graphical abstract
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Biomaterial-cell interactions significantly influence cell viability, primarily through proliferation and differentiation.
“Given that biomaterial cell interactions significantly influence cell viability, primarily through mechanisms such as proliferation and differentiation, the characteristics of biomaterials, including surface chemistry, charge, roughness, reactivity, hydrophilicity, and rigidity, necessitate careful consideration [4].”
From Resorbable Biomaterials Used for 3D Scaffolds in Tissue Engineering: A Review (2023) · cites this paper as [4]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
No references could be resolved yet.
Research works printed but not linked: 17
- Brinker CJ, Scherer GW (2013) Sol-gel science: the phy- sics and chemistry of sol-gel processing. Academic Press, Cambridge
- Baino F, Fiume E, Barberi J, Kargozar S, Marchi J, Massera J et al (2019) Processing methods for making porous bioactive glass-based scaffolds-a state-of-the-art review. Int J Appl Ceram Technol 16:1762-1796
- Fung Y-C (2013) Biomechanics: mechanical properties of living tissues. Springer, Berlin
- Driessens F (2018) Formation and stability of calcium phosphates in relation to the phase composition of the mineral in calcified tissues. In: Bioceramics of calcium phosphate. CRC Press, Boca Raton, pp 1-32
- Wacker WE (1980) Magnesium and man. Harvard University Press, Cambridge
- Abdelraof M, Farag MM, Al-Rashidy ZM, Ahmed HY, El- Saied H, Hasanin MS (2022) Green synthesis of bioactive hydroxyapatite/cellulose composites from food industrial wastes. J Inorg Organomet Polym 32(12):4614-4626
- Montazeran AH, Saber Samandari S, Khandan A (2018) Artificial intelligence investigation of three silicates bioceramics-magnetite bio-nanocomposite: hyperthermia and biomedical applications. Nanomedicine Journal 5:163-171
- Abdelaal OA, Darwish SM. Review of rapid prototyping techniques for tissue engineering scaffolds fabrication. In: Characterization and development of biosystems and bio- materials. Springer, Berlin, pp 33-54
- Eltom A, Zhong G, Muhammad A (2019) Scaffold tech- niques and designs in tissue engineering functions and purposes: a review. Adv Mater Sci Eng 2019:1-13
- Tortora GJ, Petti K (2002) Principles of human anatomy. Wiley, New York
- Kolan KC, Huang Y-W, Semon JA, Leu MC (2020) 3D- printed biomimetic bioactive glass scaffolds for bone regeneration in rat calvarial defects. Int J Bioprint 6(2):82-98
- Bozo IY, Deev RV, Smirnov IV, Fedotov AY, Popov VK, Mironov AV et al (2020) 3D printed gene-activated octa- calcium phosphate implants for large bone defects engi- neering. Int J Bioprint 6(3):93-109
- Dhivya S, Padma VV, Santhini E (2015) Wound dress- ings-a review. Biomedicine 5:1-5
- Nikolova MP, Chavali MS (2019) Recent advances in biomaterials for 3D scaffolds: a review. Bioactive Mater 4:271-292
- Vijayavenkataraman S, Lu WF, Fuh JY (2016) 3D bio- printing of skin: a state-of-the-art review on modelling, materials, and processes. Biofabrication 8:032001
- Madariaga MLL, Ott HC (2014) Bioengineering kidneys for transplantation. In: Seminars in nephrology. Elsevier, Amsterdam, pp 384-393
- Duan B (2017) State-of-the-art review of 3D bioprinting for cardiovascular tissue engineering. Ann Biomed Eng 45:195-209
Cited by
Sorted by citations
Resorbable Biomaterials Used for 3D Scaffolds in Tissue Engineering: A Review
Vach Agocsova, S., Culenova, M., Birova, I., Omanikova, L., Moncmanova, B., Danisovic, L., Ziaran, S., Bakos, D., & Alexy, P. (2023) · Materials · doi:10.3390/ma16124267 · Cited by 98 · see citing works
- Authors
- Farag, M. M.
- Affiliations
- National Research Centre (EG)
- Corresponding author
- Farag, Mohammad M.
- ORCID
- Farag, Mohammad M.
- Venue
- Journal of Materials Science
- Published
- 2023-01
- Volume
- 58
- Issue
- 2
- Pages
- 527-558
- ISSN
- 0022-2461 (ISSN-L)
- 1573-4803
- OpenAlex
- W4313377758
- Cited by
- 173
- References
- 0
- Citations by year
- 2026: 47 · 2025: 60 · 2024: 50 · 2023: 16
- FWCI
- 13.26
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Locations
- Journal of Materials Science (publishedVersion, cc-by)
- Funders
- National Research Centre Egypt
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Bone Tissue Engineering Materials
- Health Sciences › Medicine › Surgery › Tissue Engineering and Regenerative Medicine
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Medicine › Hydrogels: synthesis, properties, applications
- Keywords
- biomaterials, tissue regeneration, tissue engineering, scaffolds, scaffold fabrication, bioceramics, bioactive glass, synthetic polymers, natural polymers, polymer composites, bone regeneration, skin regeneration, cartilage regeneration, nerve regeneration, cardiac regeneration
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
