Cited by 24Seed and Plant BiochemistryBotanical Research and ChemistryPhytochemicals and Antioxidant Activities

The DOI matches its Crossref record; 35 of the 35 references it cites were found in a registry or an index.

In Vitro Assay of Quinoa (Chenopodium quinoa Willd.) and Lupin (Lupinus spp.) Extracts on Human Platelet Aggregation

Alarcón, Marcelo, Bustos, Michelle, Mendez, Diego, Fuentes, Eduardo, Palomo, Ivan, Lutz, Mariane·2020·Plant Foods for Human Nutrition

Abstract

Cardiovascular disease (CVD) is the leading cause of death throughout the world. A major risk factor for CVD is platelet aggregation. Various plant extracts exhibit anti-aggregatory action in vitro. The dietary intake of traditional plant crops such as quinoa (Chenopodium quinoa Willd) and lupin (Lupinus spp., Fabaceae family), highly recognized for their high nutritional value, is increasing worldwide. The aim of the study was to assay possible antiplatelet effects of quinoa and lupin bean extracts in vitro. The proximate chemical composition of quinoa grains and the three most widely known lupin cultivars: blue (L. angustifolius), yellow (L. luteus or mutabilis) and white (L. albus) grown in Chile were analyzed. The anti-aggregation activity of the ethanol extracts of the crops was assayed using flow cytometry in ADP-stimulated human platelets, and their inhibition of the maximal platelet aggregation was measured. All the lupin extracts exhibited a significant anti-aggregatory effect (p < 0.0001), while quinoa extracts did not exert this effect compared to control platelets. In conclusion, lupin beans extracts exhibited an anti-aggregatory effect on activated human platelets.

Overview

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Crossref · 10.1007/s11130-019-00786-y

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35 of 35 references verified0 citation errors · 0 not checkable

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Cites

Research works printed but not linked: 1

  1. Nardini M, Natella F, Scaccini C (2007) Role of dietary polyphenols in platelet aggregation. . A review of the supplementation studies. Platelets 18:224–243. https://doi.org/10.1080/09537100601078083 · DOI

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Metadata

Authors
Alarcón, M., Bustos, M., Mendez, D., Fuentes, E., Palomo, I., & Lutz, M.
Affiliations
Universidad de Talca (CL)
Venue
Plant Foods for Human Nutrition
Published
2020-02-21
Volume
75
Issue
2
Pages
215-222
ISSN
  • 0033-5134 (ISSN-L)
  • 0921-9668
  • 1573-9104
OpenAlex
W3007160980
Cited by
24
References
35
Citations by year
2026: 1 · 2025: 4 · 2024: 6 · 2023: 5 · 2022: 3 · 2021: 4 · 2020: 1
FWCI
2.11
Type
journal article
Language
en
Open access
closed
Locations
  • Plant Foods for Human Nutrition (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Seed and Plant Biochemistry
  • Life Sciences › Agricultural and Biological Sciences › Ecology, Evolution, Behavior and Systematics › Botanical Research and Chemistry
  • Health Sciences › Medicine › Biochemistry (medical) › Phytochemicals and Antioxidant Activities
Keywords
quinoa, lupin, antiplatelet activity, platelet aggregation, plant extracts, cardiovascular disease, proximate composition, Lupinus angustifolius, Lupinus luteus, Lupinus albus, Fabaceae
MeSH terms
Chile, Humans, Plant Extracts, Platelet Aggregation, Seeds, Chenopodium quinoa, Lupinus

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