Cited by 23Diabetes Management and EducationDiabetes Management and ResearchPatient-Provider Communication in Healthcare

Hypoglycemia communication in primary care visits for patients with diabetes

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Pilla, Scott J., Park, Jenny, Schwartz, Jessica L., Albert, Michael C., Ephraim, Patti L., Boulware, L. Ebony, Mathioudakis, Nestoras N., Maruthur, Nisa M. +2 more·2021·Journal of General Internal Medicine

Abstract

Background Hypoglycemia is a common and serious adverse effect of diabetes treatment, especially for patients using insulin or insulin secretagogues. Guidelines recommend that these patients be assessed for interval hypoglycemic events at each clinical encounter and be provided anticipatory guidance for hypoglycemia prevention.Objective To determine the frequency and content of hypoglycemia communication in primary care visits.Design Qualitative study PARTICIPANTS: We examined 83 primary care visits from one urban health practice representing 8 clinicians and 33 patients using insulin or insulin secretagogues.Approach Using a directed content analysis approach, we analyzed audio-recorded primary care visits collected as part of the Achieving Blood Pressure Control Together study, a randomized trial of behavioral interventions for hypertension. The coding framework included communication about interval hypoglycemia, defined as discussion of hypoglycemic events or symptoms; the components of hypoglycemia anticipatory guidance in diabetes guidelines; and hypoglycemia unawareness. Hypoglycemia documentation in visit notes was compared to visit transcripts.Key results Communication about interval hypoglycemia occurred in 24% of visits, and hypoglycemic events were reported in 16%. Despite patients voicing fear of hypoglycemia, clinicians rarely assessed hypoglycemia frequency, severity, or its impact on quality of life. Hypoglycemia anticipatory guidance was provided in 21% of visits which focused on diet and behavior change; clinicians rarely counseled on hypoglycemia treatment or avoidance of driving. Limited discussions of hypoglycemia unawareness occurred in 8% of visits. Documentation in visit notes had low sensitivity but high specificity for ascertaining interval hypoglycemia communication or hypoglycemic events, compared to visit transcripts.Conclusions In this high hypoglycemia risk population, communication about interval hypoglycemia and counseling for hypoglycemia prevention occurred in a minority of visits. There is a need to support clinicians to more regularly assess their patients' hypoglycemia burden and enhance counseling practices in order to optimize hypoglycemia prevention in primary care.

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  • Individuals may treat normal glucose values as hypoglycemic.

    “It is essential to correlate glucose readings, both from glucose meters and CGM systems, with symptoms and treatment, as individuals may experience and treat hypoglycemic symptoms without checking their glucose level (107), treat normal glucose values as hypoglycemic, or tolerate hypoglycemia without treatment either because of lack of symptoms or to avoid hyperglycemia.”

    From 6. Glycemic Goals, Hypoglycemia, and Hyperglycemic Crises: Standards of Care in Diabetes-2026. (2026) · cites this paper as [107]

    In “Communication About Interval Hypoglycemia: Frequency and Content” (page not available), the paper reports four visits in which patients worried that normal glucose readings were too low; one patient called a reading of 96 “low.” This supports mistaking a normal value for hypoglycemia, but the passage does not say those patients treated the readings as hypoglycemic episodes. (LLM, conf=0.84)

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  • Individuals may experience and treat hypoglycemic symptoms without checking their glucose level.

    “It is essential to correlate glucose readings, both from glucose meters and CGM systems, with symptoms and treatment, as individuals may experience and treat hypoglycemic symptoms without checking their glucose level (107), treat normal glucose values as hypoglycemic, or tolerate hypoglycemia without treatment either because of lack of symptoms or to avoid hyperglycemia.”

    From 6. Glycemic Goals, Hypoglycemia, and Hyperglycemic Crises: Standards of Care in Diabetes-2026. (2026) · cites this paper as [107]

    In the discussion (section 12; page not provided), the paper says that reviewing glucose readings alone is likely to miss hypoglycemic events because adherence to self-monitoring is low. This supports the possibility of events without a recorded glucose reading, but it does not establish that patients experienced symptoms and treated them without checking their glucose at the time. (LLM, conf=0.76)

    Experimental — accuracy not yet measured
  • Individuals may tolerate hypoglycemia without treatment either because of lack of symptoms or to avoid hyperglycemia.

    “It is essential to correlate glucose readings, both from glucose meters and CGM systems, with symptoms and treatment, as individuals may experience and treat hypoglycemic symptoms without checking their glucose level (107), treat normal glucose values as hypoglycemic, or tolerate hypoglycemia without treatment either because of lack of symptoms or to avoid hyperglycemia.”

    From 6. Glycemic Goals, Hypoglycemia, and Hyperglycemic Crises: Standards of Care in Diabetes-2026. (2026) · cites this paper as [107]

    The Introduction (page not provided) describes hypoglycemia unawareness: a person may have low blood glucose without autonomic symptoms. The paper does not say that people leave hypoglycemia untreated because they lack symptoms or because they want to avoid hyperglycemia. (LLM, conf=0.82)

    Experimental — accuracy not yet measured

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References 58 · Cited by 23

Authors
Pilla, S. J., Park, J., Schwartz, J. L., Albert, M. C., Ephraim, P. L., Boulware, L. E., Mathioudakis, N. N., Maruthur, N. M., Beach, M. C., & Greer, R. C.
Affiliations
  • Johns Hopkins University (US)
  • Duke University (US)
Corresponding author
Pilla, Scott J.
Venue
Journal of General Internal Medicine
Published
2021-01-21
Volume
36
Issue
6
Pages
1533-1542
ISSN
  • 0884-8734 (ISSN-L)
  • 1525-1497
OpenAlex
W3122491022
Cited by
23
References
58
Citations by year
2026: 6 · 2025: 3 · 2024: 2 · 2023: 7 · 2022: 4 · 2021: 1
FWCI
2.61
Type
journal article
Language
en
Open access
Locations
  • Journal of General Internal Medicine (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Johns Hopkins University (KL2TR003099)
  • University of Rochester
  • Rush University
  • National Institutes of Health (KL2TR003099)
  • National Heart, Lung, and Blood Institute (P50HL105187)
  • National Center for Advancing Translational Sciences
  • National Institute on Minority Health and Health Disparities
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
  • Health Sciences › Health Professions › General Health Professions › Patient-Provider Communication in Healthcare
Keywords
hypoglycemia, diabetes mellitus, primary care, patient-clinician communication, hypoglycemia prevention, hypoglycemia unawareness, insulin, insulin secretagogues, clinical guideline adherence
MeSH terms
Communication, Diabetes Mellitus, Diabetes Mellitus, Type 2, Humans, Hypoglycemia, Hypoglycemic Agents, Insulin, Primary Health Care, Quality of Life

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