Cited by 135

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Concomitant Cholecystectomy During Laparoscopic Roux-en-Y Gastric Bypass in Obese Patients Is Not Justified: A Meta-Analysis

Warschkow, Rene, Tarantino, Ignazio, Ukegjini, Kristjan, Beutner, Ulrich, Güller, Ulrich, Schmied, Bruno M., Müller, Sascha A., Schultes, Bernd, Thurnheer, Martin·2013·Obesity Surgery

Abstract

While LRYGB has become a cornerstone in the surgical treatment of morbidly obese patients, concomitant cholecystectomy during LRYGB remains a matter of debate. The aim of this meta-analysis was to estimate the rate and morbidity of subsequent cholecystectomy after laparoscopic Roux-en-Y gastric bypass (LRYGB) in obese patients. A meta-analysis was performed analyzing the rate and morbidity of subsequent cholecystectomy in patients who underwent LRYGB without concomitant cholecystectomy. Thirteen studies met the inclusion criteria. The rate of subsequent cholecystectomy was 6.8 % (95 % CI, 5.0-8.7 %) based on 6,048 obese patients who underwent LRYGB without concomitant cholecystectomy. The rate of subsequent cholecystectomy due to biliary colic or gallbladder dyskinesia was 5.3 %; due to cholecystitis, 1.0 %; choledocholithiasis, 0.2 %; and biliary pancreatitis, 0.2 %. The mortality after subsequent cholecystectomy was 0 % (95 % CI, 0-0.1 %). The surgery-related complication rate after subsequent cholecystectomy was 1.8 % (95 % CI, 0.7-3.4 %) resulting in a risk of 0.1 % (95 % CI, 0.03-0.3 %) to suffer from a cholecystectomy-related complication in patients undergoing LRYGB without concomitant cholecystectomy. A prophylactic concomitant cholecystectomy during LRYGB should be avoided in patients without cholelithiasis and exclusively be performed in patients with symptomatic biliary disease.

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Crossref · 10.1007/s11695-012-0852-4

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  • Impairment in gallbladder motility occurs in weight fluctuations and rapid weight loss, triggering the formation of biliary sludge.

    “An impairment in gallbladder motility also occurs, which triggers the formation of biliary sludge [37,38].”

    From Excess Body Weight and Gallstone Disease (2021) · cites this paper as [38]

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Research works printed but not linked: 44

  1. Kohn GP, Galanko JA, Overby DW, et al. Recent trends in bariatric surgery case volume in the United States. Surgery. 2009;146:375–80. · DOI
  2. Worni M, Guller U, Shah A, et al. Cholecystectomy concomitant with laparoscopic gastric bypass: a trend analysis of the nationwide inpatient sample from 2001 to 2008. Obes Surg. 2011;22:220–9. · DOI · Paper page
  3. Ahmed AR, O’Malley W, Johnson J, et al. Cholecystectomy during laparoscopic gastric bypass has no effect on duration of hospital stay. Obes Surg. 2007;17:1075–9. · DOI
  4. Kim JJ, Schirmer B. Safety and efficacy of simultaneous cholecystectomy at Roux-en-Y gastric bypass. Surg Obes Relat Dis. 2009;5:48–53. · DOI · Paper page
  5. Nougou A, Suter M. Almost routine prophylactic cholecystectomy during laparoscopic gastric bypass is safe. Obes Surg. 2008;18:535–9. · DOI
  6. Tarantino I, Warschkow R, Steffen T, et al. Is routine cholecystectomy justified in severely obese patients undergoing a laparoscopic Roux-en-Y gastric bypass procedure? A comparative cohort study. Obes Surg. 2011;21:1870–8. · DOI
  7. Hamad GG, Ikramuddin S, Gourash WF, et al. Elective cholecystectomy during laparoscopic Roux-en-Y gastric bypass: is it worth the wait? Obes Surg. 2003;13:76–81. · DOI · Paper page
  8. Tucker ON, Fajnwaks P, Szomstein S, et al. Is concomitant cholecystectomy necessary in obese patients undergoing laparoscopic gastric bypass surgery? Surg Endosc. 2008;22:2450–4. · DOI
  9. Villegas L, Schneider B, Provost D, et al. Is routine cholecystectomy required during laparoscopic gastric bypass? Obes Surg. 2004;14:60–6. · DOI
  10. D’Hondt M, Sergeant G, Deylgat B, et al. Prophylactic cholecystectomy, a mandatory step in morbidly obese patients undergoing laparoscopic Roux-en-Y gastric bypass? J Gastrointest Surg. 2011;15:1532–6. · DOI
  11. Ellner SJ, Myers TT, Piorkowski JR, et al. Routine cholecystectomy is not mandatory during morbid obesity surgery. Surg Obes Relat Dis. 2007;3:456–60. · DOI · Paper page
  12. Papasavas PK, Gagne DJ, Ceppa FA, et al. Routine gallbladder screening not necessary in patients undergoing laparoscopic Roux-en-Y gastric bypass. Surg Obes Relat Dis. 2006;2:41–6. · DOI
  13. Patel KR, White SC, Tejirian T, et al. Gallbladder management during laparoscopic Roux-en-Y gastric bypass surgery: routine preoperative screening for gallstones and postoperative prophylactic medical treatment are not necessary. Am Surg. 2006;72:857–61. · DOI
  14. Patel JA, Patel NA, Piper GL, et al. Perioperative management of cholelithiasis in patients presenting for laparoscopic Roux-en-Y gastric bypass: have we reached a consensus? Am Surg. 2009;75:470–6. · DOI
  15. Portenier DD, Grant JP, Blackwood HS, et al. Expectant management of the asymptomatic gallbladder at Roux-en-Y gastric bypass. Surg Obes Relat Dis. 2007;3:476–9. · DOI
  16. Swartz DE, Felix EL. Elective cholecystectomy after Roux-en-Y gastric bypass: why should asymptomatic gallstones be treated differently in morbidly obese patients? Surg Obes Relat Dis. 2005;1:555–60. · DOI · Paper page
  17. Fuller W, Rasmussen JJ, Ghosh J, et al. Is routine cholecystectomy indicated for asymptomatic cholelithiasis in patients undergoing gastric bypass? Obes Surg. 2007;17:747–51. · DOI
  18. Scott DJ, Villegas L, Sims TL, et al. Intraoperative ultrasound and prophylactic ursodiol for gallstone prevention following laparoscopic gastric bypass. Surg Endosc. 2003;17:1796–802. · DOI
  19. Tucker O, Soriano I, Szomstein S, et al. Management of choledocholithiasis after laparoscopic Roux-en-Y gastric bypass. Surg Obes Relat Dis. 2008;4:674–8. · DOI
  20. Stroup DF, Berlin JA, Morton SC, et al. Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis of Observational Studies in Epidemiology (MOOSE) group. JAMA. 2000;283:2008–12. · DOI · Paper page
  21. Hozo SP, Djulbegovic B, Hozo I. Estimating the mean and variance from the median, range, and the size of a sample. BMC Med Res Methodol. 2005;5:13. · DOI · Paper page
  22. Stang A. Critical evaluation of the Newcastle–Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses. Eur J Epidemiol. 2010;25:603–5. · DOI · Paper page
  23. DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials. 1986;7:177–88. · DOI · Paper page
  24. Freeman MF, Tukey JW. Transformations related to the angular and the square root. Ann Math Stat. 1950;21:607–11. · DOI
  25. Whitehead A, Whitehead J. A general parametric approach to the meta-analysis of randomized clinical trials. Stat Med. 1991;10:1665–77. · DOI
  26. Higgins JP, Thompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med. 2002;21:1539–58. · DOI · Paper page
  27. Begg CB, Mazumdar M. Operating characteristics of a rank correlation test for publication bias. Biometrics. 1994;50:1088–101. · DOI · Paper page
  28. Viechtbauer W. Conducting meta-analyses in R with the metafor Package. J Stat Softw. 2010;36:1–48. · DOI · Paper page
  29. Li VK, Pulido N, Fajnwaks P, et al. Predictors of gallstone formation after bariatric surgery: a multivariate analysis of risk factors comparing gastric bypass, gastric banding, and sleeve gastrectomy. Surg Endosc. 2009;23:1640–4. · DOI · Paper page
  30. Puzziferri N, Austrheim-Smith IT, Wolfe BM, et al. Three-year follow-up of a prospective randomized trial comparing laparoscopic versus open gastric bypass. Ann Surg. 2006;243:181–8. · DOI
  31. Sakorafas GH, Milingos D, Peros G. Asymptomatic cholelithiasis: is cholecystectomy really needed? A critical reappraisal 15 years after the introduction of laparoscopic cholecystectomy. Dig Dis Sci. 2007;52:1313–25. · DOI
  32. Attili AF, Carulli N, Roda E, et al. Epidemiology of gallstone disease in Italy: prevalence data of the Multicenter Italian Study on Cholelithiasis (M.I.COL.). Am J Epidemiol. 1995;141:158–65. · DOI
  33. Muhrbeck O, Ahlberg J. Prevalence of gallstone disease in a Swedish population. Scand J Gastroenterol. 1995;30:1125–8. · DOI
  34. Beckingham IJ. ABC of diseases of liver, pancreas, and biliary system. Gallstone disease. BMJ. 2001;322:91–4. · DOI
  35. Iglezias Brandao DO, Adami CE, da Silva BB. Impact of rapid weight reduction on risk of cholelithiasis after bariatric surgery. Obes Surg. 2003;13:625–8. · DOI
  36. Shiffman ML, Sugerman HJ, Kellum JM, et al. Gallstone formation after rapid weight loss: a prospective study in patients undergoing gastric bypass surgery for treatment of morbid obesity. Am J Gastroenterol. 1991;86:1000–5.
  37. Everhart JE. Contributions of obesity and weight loss to gallstone disease. Ann Intern Med. 1993;119:1029–35. · DOI · Paper page
  38. Wudel Jr LJ, Wright JK, Debelak JP, et al. Prevention of gallstone formation in morbidly obese patients undergoing rapid weight loss: results of a randomized controlled pilot study. J Surg Res. 2002;102:50–6. · DOI · Paper page
  39. Amaral JF, Thompson WR. Gallbladder disease in the morbidly obese. Am J Surg. 1985;149:551–7. · DOI · Paper page
  40. Sugerman HJ, Brewer WH, Shiffman ML, et al. A multicenter, placebo-controlled, randomized, double-blind, prospective trial of prophylactic ursodiol for the prevention of gallstone formation following gastric-bypass-induced rapid weight loss. Am J Surg. 1995;169:91–6. · DOI · Paper page
  41. Schmidt JH, Hocking MP, Rout WR, et al. The case for prophylactic cholecystectomy concomitant with gastric restriction for morbid obesity. Am Surg. 1988;54:269–72.
  42. Martinez J, Guerrero L, Byers P, et al. Endoscopic retrograde cholangiopancreatography and gastroduodenoscopy after Roux-en-Y gastric bypass. Surg Endosc. 2006;20:1548–50. · DOI
  43. Mosler P, Fogel EL. Massive subcutaneous emphysema after attempted endoscopic retrograde cholangiopancreatography in a patient with a history of bariatric gastric bypass surgery. Endoscopy. 2007;39 Suppl 1:E155. · DOI
  44. Patel JA, Patel NA, Shinde T, et al. Endoscopic retrograde cholangiopancreatography after laparoscopic Roux-en-Y gastric bypass: a case series and review of the literature. Am Surg. 2008;74:689–93. · DOI

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Metadata

Authors
Warschkow, R., Tarantino, I., Ukegjini, K., Beutner, U., Güller, U., Schmied, B. M., Müller, S. A., Schultes, B., & Thurnheer, M.
Venue
Obesity Surgery
Published
2013-01-12
Volume
23
Issue
3
Pages
397-407
ISSN
  • 0960-8923
  • 1708-0428
Cited by
135
References
0
Language
en

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