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Cited by 229Bariatric Surgery and OutcomesDiabetes, Cardiovascular Risks, and LipoproteinsDiabetes Treatment and Management

The Long-Term Effects of Bariatric Surgery on Type 2 Diabetes Remission, Microvascular and Macrovascular Complications, and Mortality: a Systematic Review and Meta-Analysis

Sheng, Binwu, Truong, Khoa, Spitler, Hugh, Zhang, Lu, Tong, Xuetao, Chen, Liwei·2017·Obesity Surgery
DOI 10.1007/s11695-017-2866-4
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Abstract

This systematic review aimed to evaluate the long-term (≥ 5 years) outcomes of bariatric surgery on diabetes remission, microvascular and macrovascular events, and mortality among type 2 diabetes (T2D) patients. Ten articles (one randomized controlled trial and nine cohorts) met the inclusion criteria and were included in this review. Pooled estimates of nine cohort studies showed that surgery significantly increased the diabetes remission (relative risk (RR) = 5.90; 95% CI 3.75-9.28), reduced the microvascular (RR = 0.37; 95% CI = 0.30-0.46) and macrovascular events (RR = 0.52; 95% CI 0.44-0.61), and mortality (RR = 0.21; 95% CI 0.20-0.21) as compared to non-surgical treatment. Available evidence suggests better remission and lower risks of microvascular and macrovascular disease and mortality in the surgery group as compared to non-surgical treatment group in T2D patients after at least 5 years of follow-up.

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  • In people with type 2 diabetes, surgical weight loss proved more effective than pharmacotherapy in reducing or even resolving hyperglycemia and was further associated with a reduction in microvascular and macrovascular complications.

    “In people with type 2 diabetes, surgical weight loss proved more effective than pharmacotherapy in reducing or even resolving hyperglycemia [90] and was further associated with a reduction in microvascular and macrovascular complications [91].”

    From Obesity and MASLD: Is weight loss the (only) key to treat metabolic liver disease? (2024) · cites this paper as [91]

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References 47 · Cited by 229

Authors
Sheng, B., Truong, K., Spitler, H., Zhang, L., Tong, X., & Chen, L.
Affiliations
  • First Affiliated Hospital of Xi'an Jiaotong University (CN)
  • Clemson University (US)
  • Guiyang Medical University (CN)
Corresponding author
Chen, Liwei
ORCID
Venue
Obesity Surgery
Publisher
Springer Science and Business Media LLC
Published
2017-08-11
Volume
27
Issue
10
Pages
2724-2732
ISSN
  • 0960-8923 (ISSN-L)
  • 1708-0428
DOI
10.1007/s11695-017-2866-4
OpenAlex
W2743808201
Cited by
229
References
47
Citations by year
2026: 7 · 2025: 24 · 2024: 28 · 2023: 42 · 2022: 27 · 2021: 32 · 2020: 33 · 2019: 20 · 2018: 12 · 2017: 2 · 2015: 1
FWCI
3.88
Type
journal article
Language
en
Open access
closed
Licence
www.springer.com/tdm (unspecified)
Locations
  • Obesity Surgery (publishedVersion)
  • PubMed (publishedVersion)
  • eScholarship (California Digital Library) (submittedVersion)
Funders
Clemson University
Topics
  • Health Sciences › Medicine › Surgery › Bariatric Surgery and Outcomes
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
Keywords
bariatric surgery, type 2 diabetes
MeSH terms
Diabetes Mellitus, Type 2, Diabetic Angiopathies, Humans, Obesity, Remission Induction, Time Factors, Cohort Studies, Randomized Controlled Trials as Topic, Bariatric Surgery

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