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Allergens from Edible Insects: Cross-reactivity and Effects of Processing

De Marchi, Laura, Wangorsch, Andrea, Zoccatelli, Gianni·2021·Current Allergy and Asthma Reports
DOI 10.1007/s11882-021-01012-zPMC PMC8165055
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Abstract

Purpose of Review: The recent introduction of edible insects in Western countries has raised concerns about their safety in terms of allergenic reactions. The characterization of insect allergens, the sensitization and cross-reactivity mechanisms, and the effects of food processing represent crucial information for risk assessment. Recent Findings: Allergic reactions to different insects and cross-reactivity with crustacean and inhalant allergens have been described, with the identification of new IgE-binding proteins besides well-known pan-allergens. Depending on the route of sensitization, different potential allergens seem to be involved. Food processing may affect the solubility and the immunoreactivity of insect allergens, with results depending on species and type of proteins. Chemical/enzymatic hydrolysis, in some cases, abolishes immunoreactivity. Summary: More studies based on subjects with a confirmed insect allergy are necessary to identify major and minor allergens and the role of the route of sensitization. The effects of processing need to be further investigated to assess the risk associated with the ingestion of insect-containing food products .

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Fig. 1 Simplified classification of the insect species discussed in the present review
Fig. 1 Simplified classification of the insect species discussed in the present reviewCC BY · PubMed Central

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Metadata

Authors
De Marchi, L., Wangorsch, A., & Zoccatelli, G.
Venue
Current Allergy and Asthma Reports
Publisher
Springer Science and Business Media LLC
Published
2021-05
Volume
21
Issue
5
ISSN
  • 1529-7322
  • 1534-6315
DOI
10.1007/s11882-021-01012-z
PMC
PMC8165055
Cited by
135
References
0
Language
en
Licence
Funders
Università degli Studi di Verona

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

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