The DOI matches its Crossref record; 64 of the 64 references it cites were found in a registry or an index.
Early Brain Injury After Poor-Grade Subarachnoid Hemorrhage
Open accessAbstract
PURPOSE OF REVIEW: Over the last years, the focus of clinical and animal research in subarachnoid hemorrhage (SAH) shifted towards the early phase after the bleeding based on the association of the early injury pattern (first 72 h) with secondary complications and poor outcome. This phase is commonly referenced as early brain injury (EBI). In this clinical review, we intended to overview commonly used definitions of EBI, underlying mechanisms, and potential treatment implications. RECENT FINDINGS: We found a large heterogeneity in the definition used for EBI comprising clinical symptoms, neuroimaging parameters, and advanced neuromonitoring techniques. Although specific treatments are currently not available, therapeutic interventions are aimed at ameliorating EBI by improving the energy/supply mismatch in the early phase after SAH. Future research integrating brain-derived biomarkers is warranted to improve our pathophysiologic understanding of EBI in order to ameliorate early injury patterns and improve patients' outcomes.
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Interplay between Cortical Spreading Depolarization and Seizures
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Metadata
- Authors
- Rass, V., & Helbok, R.
- Venue
- Current Neurology and Neuroscience Reports
- Published
- 2019-08-29
- Volume
- 19
- Issue
- 10
- Pages
- 78-78
- ISSN
- 1528-4042 (ISSN-L)
- 1534-6293
- OpenAlex
- W2970844985
- Cited by
- 253
- References
- 64
- FWCI
- 14.00
- Type
- journal article
- Language
- en
- Open access
- hybrid
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
