Infertility and Perinatal Loss: When the Bough Breaks
Open accessAbstract
Infertility and perinatal loss are common, and associated with lower quality of life, marital discord, complicated grief, major depressive disorder, anxiety disorders, and post-traumatic stress disorder. Young women, who lack social supports, have experienced recurrent pregnancy loss or a history of trauma and / or preexisting psychiatric illness are at a higher risk of experiencing psychiatric illnesses or symptoms after a perinatal loss or during infertility. It is especially important to detect, assess, and treat depression, anxiety, or other psychiatric symptoms because infertility or perinatal loss may be caused or perpetuated by such symptoms. Screening, psychoeducation, provision of resources and referrals, and an opportunity to discuss their loss and plan for future pregnancies can facilitate addressing mental health concerns that arise. Women at risk of or who are currently experiencing psychiatric symptoms should receive a comprehensive treatment plan that includes the following: (1) proactive clinical monitoring, (2) evidence-based approaches to psychotherapy, and (3) discussion of risks, benefits, and alternatives of medication treatment during preconception and pregnancy.
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Lack of social support is a risk factor for prolonged grief.
“Bhat and colleagues’ study has shown that the lack of social support is a risk factor for prolonged grief. 41”
From Desired Care for Perinatal Bereavement: Meeting the Needs of Mothers After Discharge From the Hospital—a Qualitative Study (2024) · cites this paper as [41]
The Grief section identifies lack of social support as a predictor of complicated grief following perinatal loss, and the Conclusions repeat that finding. The citing sentence omits the perinatal-loss context, so the paper does not establish the risk factor for prolonged grief after losses generally. (LLM, conf=0.84)
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References 111 · Cited by 106
- Authors
- Bhat, A., & Byatt, N.
- Affiliations
- University of Washington (US)
- University of Massachusetts Chan Medical School (US)
- Corresponding author
- Bhat, Amritha
- Venue
- Current Psychiatry Reports
- Published
- 2016-02-05
- Volume
- 18
- Issue
- 3
- Pages
- 31-31
- ISSN
- 1523-3812 (ISSN-L)
- 1535-1645
- PMC
- PMC4896304
- OpenAlex
- W2258287631
- Cited by
- 106
- References
- 111
- Citations by year
- 2026: 8 · 2025: 13 · 2024: 19 · 2023: 10 · 2022: 9 · 2021: 19 · 2020: 15 · 2019: 2 · 2018: 5 · 2017: 4 · 2016: 1 · 2012: 1
- FWCI
- 0.59
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Current Psychiatry Reports (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- The Journal of the American Medical Association (JAMA) Network (American Medical Association) (submittedVersion)
- Funders
- National Institutes of Health (KL2TR001455, KL2TR000160, 2t32mh020021-26)
- National Institute of Mental Health (T-32MH020021, T32-MH20021)
- National Center for Advancing Translational Sciences
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Health Sciences › Medicine › Reproductive Medicine › Reproductive Health and Technologies
- Social Sciences › Psychology › Clinical Psychology › Grief, Bereavement, and Mental Health
- Keywords
- infertility, perinatal loss, recurrent pregnancy loss, maternal mental health, depression, anxiety disorders, post-traumatic stress disorder, complicated grief, mental health screening, psychoeducation, psychotherapy, drug use in pregnancy, preconception care, social support
- MeSH terms
- Anxiety, Anxiety Disorders, Depression, Major Depressive Disorder, Female, Grief, Humans, Infertility, Pregnancy, Quality of Life, Stress Disorders, Post-Traumatic, Stillbirth
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