The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Amyloid β-Peptide 1–42 Modulates the Proliferation of Mouse Neural Stem Cells: Upregulation of Fucosyltransferase IX and Notch Signaling
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“We identified several DEGs that have been previously associated with lipid metabolism, including MIAT, COMT, NRP1, VEGFB, GRAMD1B, DSEL56–62, as well as FUT9 associated with glycan structure63,64 (Fig. 4a).”
From GRAMD1B is a regulator of lipid homeostasis, autophagic flux and phosphorylated tau (2025) · cites this paper as [63]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Isolation and quantification of soluble Alzheimer's β-peptide from biological fluids
Seubert, P., Vigo-Pelfrey, C., Esch, F., Lee, M., Dovey, H., Davis, D., Sinha, S., Schiossmacher, M., Whaley, J., Swindlehurst, C., et al. (1992) · Nature · doi:10.1038/359325a0 · Cited by 1,731
Aβ1–42 stimulates adult SVZ neurogenesis through the p75 neurotrophin receptor
Sotthibundhu, A., Li, Q.-X., Thangnipon, W., & Coulson, E. J. (2009) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2008.02.004 · Cited by 81
Flagged first, then by citations
Research works printed but not linked: 62
- Selkoe DJ (1997) Alzheimer’s disease: genotypes, phenotypes, and treatments. Science 275(5300):630–631 · DOI
- Benilova I, Karran E, De Strooper B (2012) The toxic Abeta oligomer and Alzheimer’s disease: an emperor in need of clothes. Nat Neurosci 15(3):349–357. doi: 10.1038/nn.3028 nn.3028 · DOI · Paper page
- Hardy J, Selkoe DJ (2002) The amyloid hypothesis of Alzheimer’s disease: progress and problems on the road to therapeutics. Science 297(5580):353–356. doi: 10.1126/science.1072994 297/5580/353 · DOI · Paper page
- Itokazu Y, Kato-Negishi M, Nakatani Y, Ariga T, Yu RK (2013) Effects of amyloid beta-peptides and gangliosides on mouse neural stem cells. Neurochem Res. doi: 10.1007/s11064-013-1108-y · DOI
- Haass C, Schlossmacher MG, Hung AY, Vigo-Pelfrey C, Mellon A, Ostaszewski BL, Lieberburg I, Koo EH, Schenk D, Teplow DB et al (1992) Amyloid beta-peptide is produced by cultured cells during normal metabolism. Nature 359(6393):322–325. doi: 10.1038/359322a0 · DOI · Paper page
- Shoji M (2002) Cerebrospinal fluid Abeta40 and Abeta42: natural course and clinical usefulness. Front Biosci 7:d997–d1006 · DOI
- Yu RK, Nakatani Y, Yanagisawa M (2009) The role of glycosphingolipid metabolism in the developing brain. J Lipid Res 50(Suppl):S440–S445. doi: 10.1194/jlr.R800028-JLR200 · DOI
- Yu RK, Tsai YT, Ariga T (2012) Functional roles of gangliosides in neurodevelopment: an overview of recent advances. Neurochem Res 37(6):1230–1244. doi: 10.1007/s11064-012-0744-y · DOI
- Ngamukote S, Yanagisawa M, Ariga T, Ando S, Yu RK (2007) Developmental changes of glycosphingolipids and expression of glycogenes in mouse brains. J Neurochem 103(6):2327–2341. doi: 10.1111/j.1471-4159.2007.04910.x · DOI
- Yu RK, Macala LJ, Taki T, Weinfield HM, Yu FS (1988) Developmental changes in ganglioside composition and synthesis in embryonic rat brain. J Neurochem 50(6):1825–1829 · DOI
- Eisenbarth GS, Walsh FS, Nirenberg M (1979) Monoclonal antibody to a plasma membrane antigen of neurons. Proc Natl Acad Sci U S A 76(10):4913–4917 · DOI
- Kasai N, Yu RK (1983) The monoclonal antibody A2B5 is specific to ganglioside GQ1c. Brain Res 277(1):155–158 · DOI
- Saito M, Kitamura H, Sugiyama K (2001) The specificity of monoclonal antibody A2B5 to c-series gangliosides. J Neurochem 78(1):64–74 · DOI
- Majocha RE, Jungalwala FB, Rodenrys A, Marotta CA (1989) Monoclonal antibody to embryonic CNS antigen A2B5 provides evidence for the involvement of membrane components at sites of Alzheimer degeneration and detects sulfatides as well as gangliosides. J Neurochem 53(3):953–961 · DOI
- Freischutz B, Saito M, Rahmann H, Yu RK (1994) Activities of five different sialyltransferases in fish and rat brains. J Neurochem 62(5):1965–1973 · DOI
- Rosner H, Greis C, Henke-Fahle S (1988) Developmental expression in embryonic rat and chicken brain of a polysialoganglioside-antigen reacting with the monoclonal antibody Q 211. Brain Res 470(2):161–171 · DOI
- Raff MC, Miller RH, Noble M (1983) A glial progenitor cell that develops in vitro into an astrocyte or an oligodendrocyte depending on culture medium. Nature 303(5916):390–396 · DOI
- Crino PB, Ullman MD, Vogt BA, Bird ED, Volicer L (1989) Brain gangliosides in dementia of the Alzheimer type. Arch Neurol 46(4):398–401 · DOI
- Kalanj S, Kracun I, Rosner H, Cosovic C (1991) Regional distribution of brain gangliosides in Alzheimer's disease. Neurol Croat 40(4):269–281
- Kracun I, Kalanj S, Cosovic C, Talan-Hranilovic J (1990) Brain gangliosides in Alzheimer’s disease. J Hirnforsch 31(6):789–793
- Kracun I, Kalanj S, Talan-Hranilovic J, Cosovic C (1992) Cortical distribution of gangliosides in Alzheimer’s disease. Neurochem Int 20(3):433–438 · DOI
- Svennerholm L, Gottfries CG (1994) Membrane lipids, selectively diminished in Alzheimer brains, suggest synapse loss as a primary event in early-onset form (type I) and demyelination in late-onset form (type II). J Neurochem 62(3):1039–1047 · DOI
- Barrier L, Ingrand S, Damjanac M, Rioux Bilan A, Hugon J, Page G (2007) Genotype-related changes of ganglioside composition in brain regions of transgenic mouse models of Alzheimer’s disease. Neurobiol Aging 28(12):1863–1872. doi: 10.1016/j.neurobiolaging.2006.08.002 · DOI
- Ariga T, Yanagisawa M, Wakade C, Ando S, Buccafusco JJ, McDonald MP, Yu RK (2010) Ganglioside metabolism in a transgenic mouse model of Alzheimer’s disease: expression of Chol-1alpha antigens in the brain. ASN Neuro 2(4):e00044. doi: 10.1042/AN20100021 · DOI
- Cazzaniga E, Bulbarelli A, Cassetti A, Lonati E, Re F, Palestini P, Mutoh T, Masserini M (2007) Beta-amyloid (25–35) enhances lipid metabolism and protein ubiquitination in cultured neurons. J Neurosci Res 85(10):2253–2261. doi: 10.1002/jnr.21354 · DOI
- Copani A, Melchiorri D, Caricasole A, Martini F, Sale P, Carnevale R, Gradini R, Sortino MA, Lenti L, De Maria R, Nicoletti F (2002) Beta-amyloid-induced synthesis of the ganglioside GD3 is a requisite for cell cycle reactivation and apoptosis in neurons. J Neurosci 22(10):3963–3968 · DOI
- Yanagisawa M, Yu RK (2007) The expression and functions of glycoconjugates in neural stem cells. Glycobiology 17(7):57R–74R. doi: 10.1093/glycob/cwm018 · DOI
- Kudo T, Ikehara Y, Togayachi A, Kaneko M, Hiraga T, Sasaki K, Narimatsu H (1998) Expression cloning and characterization of a novel murine alpha1, 3-fucosyltransferase, mFuc-TIX, that synthesizes the Lewis x (CD15) epitope in brain and kidney. J Biol Chem 273(41):26729–26738 · DOI
- Yagi H, Saito T, Yanagisawa M, Yu RK, Kato K (2012) Lewis X-carrying N-glycans regulate the proliferation of mouse embryonic neural stem cells via the Notch signaling pathway. J Biol Chem 287(29):24356–24364. doi: 10.1074/jbc.M112.365643 · DOI
- Nakatani Y, Yanagisawa M, Suzuki Y, Yu RK (2010) Characterization of GD3 ganglioside as a novel biomarker of mouse neural stem cells. Glycobiology 20(1):78–86. doi: 10.1093/glycob/cwp149 · DOI
- Kanemura Y, Mori H, Kobayashi S, Islam O, Kodama E, Yamamoto A, Nakanishi Y, Arita N, Yamasaki M, Okano H, Hara M, Miyake J (2002) Evaluation of in vitro proliferative activity of human fetal neural stem/progenitor cells using indirect measurements of viable cells based on cellular metabolic activity. J Neurosci Res 69(6):869–879. doi: 10.1002/jnr.10377 · DOI
- Yanagisawa M, Yu RK (2009) O-linked beta-N-acetylglucosaminylation in mouse embryonic neural precursor cells. J Neurosci Res 87(16):3535–3545. doi: 10.1002/jnr.22170 · DOI
- Chen Y, Dong C (2009) Abeta40 promotes neuronal cell fate in neural progenitor cells. Cell Death Differ 16(3):386–394. doi: 10.1038/cdd.2008.94 · DOI · Paper page
- Heo C, Chang KA, Choi HS, Kim HS, Kim S, Liew H, Kim JA, Yu E, Ma J, Suh YH (2007) Effects of the monomeric, oligomeric, and fibrillar Abeta42 peptides on the proliferation and differentiation of adult neural stem cells from subventricular zone. J Neurochem 102(2):493–500. doi: 10.1111/j.1471-4159.2007.04499.x · DOI
- Lopez-Toledano MA, Shelanski ML (2004) Neurogenic effect of beta-amyloid peptide in the development of neural stem cells. J Neurosci 24(23):5439–5444. doi: 10.1523/JNEUROSCI.0974-04.2004 24/23/5439 · DOI · Paper page
- Yanagisawa M, Ariga T, Yu RK (2010) Cytotoxic effects of G(M1) ganglioside and amyloid beta-peptide on mouse embryonic neural stem cells. ASN Neuro 2(1):e00029. doi: 10.1042/AN20090063 · DOI
- Yagi H, Yanagisawa M, Kato K, Yu RK (2010) Lysosome-associated membrane protein 1 is a major SSEA-1-carrier protein in mouse neural stem cells. Glycobiology 20(8):976–981. doi: 10.1093/glycob/cwq054 · DOI
- Svennerholm L (1963) Chromatographic separation of human brain gangliosides. J Neurochem 10:613–623 · DOI
- Recommendations (1976) IUPAC-IUB Commission on Biochemical Nomenclature (1977) The nomenclature of lipids. Lipids 12(6):455–468 · DOI
- Sansom SN, Griffiths DS, Faedo A, Kleinjan DJ, Ruan Y, Smith J, van Heyningen V, Rubenstein JL, Livesey FJ (2009) The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis. PLoS Genet 5(6):e1000511. doi: 10.1371/journal.pgen.1000511 · DOI
- Shimoda Y, Tajima Y, Osanai T, Katsume A, Kohara M, Kudo T, Narimatsu H, Takashima N, Ishii Y, Nakamura S, Osumi N, Sanai Y (2002) Pax6 controls the expression of Lewis x epitope in the embryonic forebrain by regulating alpha 1,3-fucosyltransferase IX expression. J Biol Chem 277(3):2033–2039. doi: 10.1074/jbc.M108495200 · DOI
- Imai T, Tokunaga A, Yoshida T, Hashimoto M, Mikoshiba K, Weinmaster G, Nakafuku M, Okano H (2001) The neural RNA-binding protein Musashi1 translationally regulates mammalian numb gene expression by interacting with its mRNA. Mol Cell Biol 21(12):3888–3900. doi: 10.1128/MCB.21.12.3888-3900.2001 · DOI
- Okano H, Kawahara H, Toriya M, Nakao K, Shibata S, Imai T (2005) Function of RNA-binding protein Musashi-1 in stem cells. Exp Cell Res 306(2):349–356. doi: 10.1016/j.yexcr.2005.02.021 · DOI
- Selkoe DJ (1999) Translating cell biology into therapeutic advances in Alzheimer’s disease. Nature 399(6738 Suppl):A23–A31 · DOI · Paper page
- Roher AE, Chaney MO, Kuo YM, Webster SD, Stine WB, Haverkamp LJ, Woods AS, Cotter RJ, Tuohy JM, Krafft GA, Bonnell BS, Emmerling MR (1996) Morphology and toxicity of Abeta-(1–42) dimer derived from neuritic and vascular amyloid deposits of Alzheimer’s disease. J Biol Chem 271(34):20631–20635 · DOI
- Yan Y, Wang C (2006) Abeta42 is more rigid than Abeta40 at the C terminus: implications for Abeta aggregation and toxicity. J Mol Biol 364(5):853–862. doi: 10.1016/j.jmb.2006.09.046 · DOI
- Yang M, Teplow DB (2008) Amyloid beta-protein monomer folding: free-energy surfaces reveal alloform-specific differences. J Mol Biol 384(2):450–464. doi: 10.1016/j.jmb.2008.09.039 · DOI
- Kaminsky YG, Marlatt MW, Smith MA, Kosenko EA (2010) Subcellular and metabolic examination of amyloid-beta peptides in Alzheimer disease pathogenesis: evidence for Abeta(25–35). Exp Neurol 221(1):26–37. doi: 10.1016/j.expneurol.2009.09.005 · DOI
- Lau TL, Ambroggio EE, Tew DJ, Cappai R, Masters CL, Fidelio GD, Barnham KJ, Separovic F (2006) Amyloid-beta peptide disruption of lipid membranes and the effect of metal ions. J Mol Biol 356(3):759–770. doi: 10.1016/j.jmb.2005.11.091 · DOI
- Lau TL, Gehman JD, Wade JD, Perez K, Masters CL, Barnham KJ, Separovic F (2007) Membrane interactions and the effect of metal ions of the amyloidogenic fragment Abeta(25-35) in comparison to Abeta(1-42). Biochim Biophys Acta 1768(10):2400–2408. doi: 10.1016/j.bbamem.2007.05.004 · DOI
- Mattson MP, Begley JG, Mark RJ, Furukawa K (1997) Abeta25-35 induces rapid lysis of red blood cells: contrast with Abeta1-42 and examination of underlying mechanisms. Brain Res 771(1):147–153 · DOI
- Varadarajan S, Kanski J, Aksenova M, Lauderback C, Butterfield DA (2001) Different mechanisms of oxidative stress and neurotoxicity for Alzheimer’s A beta(1–42) and A beta(25–35). J Am Chem Soc 123(24):5625–5631 · DOI · Paper page
- Miller BL, Williams TD, Schoneich C (1996) Mechanism of sulfoxide formation through reaction of sulfur radical cation complexes with superoxide or hydroxide ion in oxygenated aqueous solution. J Am Chem Soc 118(45):11014–11025. doi: 10.1021/Ja962032l · DOI
- Pike CJ, Walencewicz-Wasserman AJ, Kosmoski J, Cribbs DH, Glabe CG, Cotman CW (1995) Structure-activity analyses of beta-amyloid peptides: contributions of the beta 25-35 region to aggregation and neurotoxicity. J Neurochem 64(1):253–265 · DOI · Paper page
- Varadarajan S, Yatin S, Kanski J, Jahanshahi F, Butterfield DA (1999) Methionine residue 35 is important in amyloid beta-peptide-associated free radical oxidative stress. Brain Res Bull 50(2):133–141 · DOI
- Yu RK, Ando S (1980) Structures of some new complex gangliosides of fish brain. Adv Exp Med Biol 125:33–45 · DOI
- Ando S, Yu RK (1979) Isolation and characterization of two isomers of brain tetrasialogangliosides. J Biol Chem 254(23):12224–12229 · DOI
- Comelli EM, Amado M, Lustig SR, Paulson JC (2003) Identification and expression of Neu4, a novel murine sialidase. Gene 321:155–161 · DOI
- Shiozaki K, Koseki K, Yamaguchi K, Shiozaki M, Narimatsu H, Miyagi T (2009) Developmental change of sialidase neu4 expression in murine brain and its involvement in the regulation of neuronal cell differentiation. J Biol Chem 284(32):21157–21164. doi: 10.1074/jbc.M109.012708 · DOI
- Tringali C, Cirillo F, Lamorte G, Papini N, Anastasia L, Lupo B, Silvestri I, Tettamanti G, Venerando B (2012) NEU4L sialidase overexpression promotes beta-catenin signaling in neuroblastoma cells, enhancing stem-like malignant cell growth. Int J Cancer 131(8):1768–1778. doi: 10.1002/ijc.27450 · DOI
- Solter D, Knowles BB (1978) Monoclonal antibody defining a stage-specific mouse embryonic antigen (SSEA-1). Proc Natl Acad Sci U S A 75(11):5565–5569 · DOI
- Gooi HC, Feizi T, Kapadia A, Knowles BB, Solter D, Evans MJ (1981) Stage-specific embryonic antigen involves alpha 1 goes to 3 fucosylated type 2 blood group chains. Nature 292(5819):156–158 · DOI
Cited by
Sorted by citations
GRAMD1B is a regulator of lipid homeostasis, autophagic flux and phosphorylated tau
Acosta Ingram, D., Turkes, E., Kim, T. Y., Vo, S., Sweeney, N., Bonte, M.-A., Rutherford, R., Julian, D. L., Pan, M., Marsh, J., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-58585-w · Cited by 12
Metadata
- Authors
- Itokazu, Y., & Yu, R. K.
- Venue
- Molecular Neurobiology
- Published
- 2014-01-17
- Volume
- 50
- Issue
- 1
- Pages
- 186-196
- ISSN
- 0893-7648
- 1559-1182
- PMC
- PMC4102671
- Cited by
- 27
- References
- 2
- Language
- en
- Licence
- www.springer.com/tdm (tdm)
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review