Cited by 12Connective tissue disorders researchGrowth Hormone and Insulin-like Growth FactorsBody Composition Measurement Techniques

Considerations for Anthropometry Specific to People with Disproportionate Short Stature

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Hoover-Fong, Julie, Semler, Oliver, Barron, Bobbie, Collett‑Solberg, Paulo Ferrez, Fung, Ellen, Irving, Melita, Kitaoka, Taichi, Koerner, Celide +4 more·2025·Advances in Therapy

Abstract

In the clinical care of people with disproportionate short stature, healthcare practitioners need to accurately collect anthropometric measurements over time, including height, weight, head circumference, and lengths of affected limb and body segments. Accurate anthropometric measurements are important for diagnostic evaluation, tracking growth, measuring response to pharmacologic therapies or surgeries, and monitoring for potential complications. However, for this clinical population, anthropometric measurements may need to be adjusted or modified to accommodate characteristics such as body disproportions, joint contractures, long bone deformities, spinal deformities, or muscle hypotonia. This article provides guidance for key anthropometric measurements in children and adults with disproportionate short stature, with a focus on people with achondroplasia. The measurements described in this article and illustrated in the infographics can be performed without expensive specialized equipment and are suitable for a variety of clinical settings.

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  • The wide range of methods and contexts in which anthropometry is applied has created a growing need for written protocols, equipment calibration, and standardized training to ensure data accuracy and comparability.

    “The wide range of methods and contexts in which anthropometry is applied has created a growing need for written protocols, equipment calibration, and standardized training to ensure data accuracy and comparability [7].”

    From The Seven Methods for the Evaluation of Nutritional Status—ABCDEFG: Narrative Review (2026) · cites this paper as [7]

    The Key Summary Points say that a written local SOP, personnel training, and equipment calibration improve measurement reproducibility for people with disproportionate short stature. The General Considerations section also addresses accuracy and consistency across clinical and research settings, but it does not establish a growing need caused by the widening range of anthropometry applications. (LLM, conf=0.84)

    Experimental — accuracy not yet measured

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Authors
Hoover-Fong, J., Semler, O., Barron, B., Collett‑Solberg, P. F., Fung, E., Irving, M., Kitaoka, T., Koerner, C., Okada, K., Palm, K., Sousa, S. B., & Mohnike, K.
Affiliations
  • Johns Hopkins University (US)
  • University of Cologne (DE)
  • UCSF Benioff Children's Hospital (US)
  • Guy's and St Thomas' NHS Foundation Trust (GB)
  • The University of Osaka (JP)
  • University of Tokyo Hospital (JP)
  • Otto-von-Guericke-Universität Magdeburg (DE)
  • Unidade Local de Saúde de Coimbra (PT)
Corresponding author
Hoover-Fong, Julie
Venue
Advances in Therapy
Published
2025-02-05
Volume
42
Issue
3
Pages
1291-1311
ISSN
  • 0741-238X (ISSN-L)
  • 1865-8652
OpenAlex
W4407175734
Cited by
12
References
0
Citations by year
2026: 8 · 2025: 4
FWCI
1.84
Type
journal article
Language
en
Open access
Locations
  • Advances in Therapy (publishedVersion, cc-by-nc)
  • PubMed Central (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
  • Figshare (acceptedVersion, cc-by-nc)
  • Figshare
Funders
BioMarin Pharmaceutical
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Connective tissue disorders research
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Growth Hormone and Insulin-like Growth Factors
  • Health Sciences › Medicine › Physiology › Body Composition Measurement Techniques
Keywords
disproportionate short stature, anthropometry, achondroplasia, head circumference, limb length, body segment length, spinal deformity, joint contractures, hypotonia, long bone deformity, growth monitoring, pediatric and adult patients
MeSH terms
Achondroplasia, Adult, Anthropometry, Body Height, Body Weight, Child, Female, Growth Disorders, Humans, Male

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