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Vibrational spectroscopic mapping and imaging of tissues and cells
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Vibrational spectroscopic mapping (point-by-point measurement) and imaging of biological samples (cells and tissues) covering Fourier-transform infrared (FTIR) and Raman spectroscopies has opened up many exciting new avenues to explore biochemical architecture and processes within healthy and diseased cells and tissues, including medical diagnostics and drug design.
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“Beyond these biochemical assays, efforts have been made to employ advanced spectroscopic techniques to capture spatial and compositional changes associated with treatment response [311,312,313].”
From Modeling Tumor Microenvironment Complexity In Vitro: Spheroids as Physiologically Relevant Tumor Models and Strategies for Their Analysis (2025) · cites this paper as [312]
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Fourier Transform Infrared Spectrometry
Griffiths, P. R., & de Haseth, J. A. (2007) · doi:10.1002/047010631x · Cited by 3,052
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Cited by
Shah, S., & D’Souza, G. G. M. (2025) · Cells · doi:10.3390/cells14100732 · Cited by 83
Zhang, J. Z., Bryce, N. S., Siegele, R., Carter, E. A., Paterson, D., de Jonge, M. D., Howard, D. L., Ryan, C. G., & Hambley, T. W. (2012) · Integrative Biology · doi:10.1039/c2ib20121f · Cited by 37
Self-citation
Metadata
- Authors
- Carter, E. A., Tam, K. K., Armstrong, R. S., & Lay, P. A.
- Affiliations
- The University of Sydney (AU)
- Corresponding author
- Lay, Peter A.
- Venue
- Biophysical Reviews
- Published
- 2009-06-23
- Volume
- 1
- Issue
- 2
- Pages
- 95-103
- ISSN
- 1867-2450 (ISSN-L)
- 1867-2469
- PMC
- PMC5418372
- OpenAlex
- W2101270900
- Cited by
- 41
- References
- 1
- Citations by year
- 2026: 1 · 2025: 2 · 2023: 4 · 2022: 1 · 2021: 1 · 2020: 1 · 2019: 3 · 2018: 2 · 2017: 2 · 2016: 6 · 2015: 2 · 2014: 5 · 2013: 1 · 2012: 4
- FWCI
- 0.39
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Biophysical Reviews (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Australian Synchrotron
- University of Sydney
- University of Technology Sydney
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biophysics › Spectroscopy Techniques in Biomedical and Chemical Research
- Physical Sciences › Physics and Astronomy › Atomic and Molecular Physics, and Optics › Spectroscopy and Quantum Chemical Studies
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Optical Imaging and Spectroscopy Techniques
- Keywords
- vibrational imaging, FTIR spectroscopy, Raman spectroscopy, tissue biochemistry, cell biochemistry, medical diagnostics, drug design
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