Resection of isolated port site metastasis in gall bladder cancers-careful selection and perioperative systemic therapy may improve outcomes
Open accessAbstract
Excision of port site (PSE) for patients having undergone laparoscopic cholecystectomy (LC) is not a standard recommendation. We retrospectively evaluated a cohort of patients with isolated PSM without any prior cancer-directed therapy who were assessed for resection between March 2012 and July 2016 at Tata Memorial Hospital, Mumbai. Eleven of a total 13 patients underwent wide excision for PSM in the given time period. Upfront resection was undertaken in six patients while seven patients received neoadjuvant chemotherapy (NACT) and two received neoadjuvant chemo radiotherapy (NACTRT) prior to attempted resection. With the median follow-up of 22 months, post PSM disease-free survival (DFS) was 20 months (95% CI 15-24 months) and overall survival (OS) was 37 months (95% CI 22-51 months). Careful selection along with an aggressive management strategy may be a step forward in the treatment of patients with isolated PSM.
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In a retrospective analysis of patients with solitary port-site metastasis, median overall survival was 37 months and post-port-site-metastasis disease-free survival was 20 months, with a median follow-up of 22 months.
“Overall survival (OS) was 37 months, and post-PSM disease-free survival (DFS) was 20 months, with a median follow-up of 22 months.”
From Insights Into Laparoscopic Port Site Complications: A Comprehensive Review (2024) · cites this paper as [26]
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References 17 · Cited by 6
- Authors
- Agarwala, V., Ramaswamy, A., Dsouza, S., Pande, N., Goel, M., Patkar, S., & Ostwal, V.
- Affiliations
- Tata Memorial Hospital (IN)
- Corresponding author
- Ostwal, Vikas
- Venue
- Indian Journal of Surgical Oncology
- Published
- 2018-08-10
- Volume
- 9
- Issue
- 3
- Pages
- 427-431
- ISSN
- 0975-7651 (ISSN-L)
- 0976-6952
- PMC
- PMC6154350
- OpenAlex
- W2886077939
- Cited by
- 6
- References
- 17
- Citations by year
- 2026: 1 · 2024: 1 · 2023: 1 · 2022: 1 · 2021: 1 · 2020: 1
- FWCI
- 0.52
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Indian Journal of Surgical Oncology (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Cholangiocarcinoma and Gallbladder Cancer Studies
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Gallbladder and Bile Duct Disorders
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Gastric Cancer Management and Outcomes
- Keywords
- port-site metastasis, gallbladder cancer, surgical resection, neoadjuvant chemotherapy, neoadjuvant chemoradiotherapy, perioperative systemic therapy, disease-free survival, overall survival, patient selection
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