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Cited by 391

The DOI matches its Crossref record; 201 of the 201 references it cites were found in a registry or an index.

In vitro and in vivo toxicity assessment of nanoparticles

Open access
Kumar, Vinay, Sharma, Neha, Maitra, S. S.·2017·International Nano Letters

Abstract

Nanotechnology has revolutionized gene therapy, diagnostics and environmental remediation. Their bulk production, uses and disposal have posed threat to the environment. With the appearance of these nanoparticles in the environment, their toxicity assessment is an immediate concern. This review is an attempt to summarize the major techniques used in cytotoxity determination. The review also presents a detailed and elaborative discussion on the toxicity imposed by different types of nanoparticles including carbon nanotubes, gold nanoparticles, silver nanoparticles, quantum dots, fullerenes, aluminium nanoparticles, zinc nanoparticles, iron nanoparticles, titanium nanoparticles and silica nanoparticles. It discusses the in vitro and in vivo toxological effects of nanoparticles on bacteria, microalgae, zebrafish, crustacean, fish, rat, mouse, pig, guinea pig, human cell lines and human. It also discusses toxological effects on organs such as liver, kidney, spleen, sperm, neural tissues, liver lysosomes, spleen macrophages, glioblastoma cells, hematoma cells and various mammalian cell lines. It provides information about the effects of nanoparticles on the gene-expression, growth and reproduction of the organisms.

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Crossref · 10.1007/s40089-017-0221-3

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Metadata

Authors
Kumar, V., Sharma, N., & Maitra, S. S.
Venue
International Nano Letters
Published
2017-11-25
Volume
7
Issue
4
Pages
243-256
ISSN
  • 2008-9295 (ISSN-L)
  • 2228-5326
OpenAlex
W2770081907
Cited by
391
References
201
FWCI
9.48
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: In vitro and in vivo toxicity assessment of nanoparticles. https://app.cochat.ai/papers/10.1007/s40089-017-0221-3
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Kumar, V., Sharma, N., & Maitra, S. S. (2017). In vitro and in vivo toxicity assessment of nanoparticles. International Nano Letters. https://doi.org/10.1007/s40089-017-0221-3

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