The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Recent Advances in Tumor Microenvironment Hydrogen Peroxide-Responsive Materials for Cancer Photodynamic Therapy
Open accessAbstract
Photodynamic therapy (PDT), as one of the noninvasive clinical cancer phototherapies, suffers from the key drawback associated with hypoxia at the tumor microenvironment (TME), which plays an important role in protecting tumor cells from damage caused by common treatments. High concentration of hydrogen peroxide (H 2 O 2), one of the hallmarks of TME, has been recognized as a double-edged sword, posing both challenges, and opportunities for cancer therapy. The promising perspectives, strategies, and approaches for enhanced tumor therapies, including PDT, have been developed based on the fast advances in H 2 O 2-enabled theranostic nanomedicine. In this review, we outline the latest advances in H 2 O 2-responsive materials, including organic and inorganic materials for enhanced PDT. Finally, the challenges and opportunities for further research on H 2 O 2-responsive anticancer agents are envisioned.
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Cites
New horizons in tumor microenvironment biology: challenges and opportunities
Chen, F., Zhuang, X., Lin, L., Yu, P., Wang, Y., Shi, Y., Hu, G., & Sun, Y. (2015) · BMC Medicine · doi:10.1186/s12916-015-0278-7 · Cited by 704
Wang, C., Cao, F., Ruan, Y., Jia, X., Zhen, W., & Jiang, X. (2019) · Angewandte Chemie International Edition · doi:10.1002/anie.201903981 · Cited by 411
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Phototherapy in cancer treatment: strategies and challenges
Cai, Y., Chai, T., Nguyen, W., Liu, J., Xiao, E., Ran, X., Ran, Y., Du, D., Chen, W., & Chen, X. (2025) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-025-02140-y · Cited by 453
Tian, H., Zhang, T., Qin, S., Huang, Z., Zhou, L., Shi, J., Nice, E. C., Xie, N., Huang, C., & Shen, Z. (2022) · Journal of Hematology & Oncology · doi:10.1186/s13045-022-01320-5 · Cited by 426
Stimuli-Responsive Polymer-Based Nanosystems for Cancer Theranostics
Wei, D., Sun, Y., Zhu, H., & Fu, Q. (2023) · ACS Nano · doi:10.1021/acsnano.3c06019 · Cited by 303
Recent advances of cancer chemodynamic therapy based on Fenton/Fenton-like chemistry
Cao, C., Wang, X., Yang, N., Song, X., & Dong, X. (2022) · Chemical Science · doi:10.1039/d1sc05482a · Cited by 298
Self-citation
Metadata
- Authors
- Yang, N., Xiao, W., Song, X., Wang, W., & Dong, X.
- Venue
- Nano-Micro Letters
- Published
- 2020-01-03
- Volume
- 12
- Issue
- 1
- Pages
- 15-15
- ISSN
- 2150-5551 (ISSN-L)
- 2311-6706
- OpenAlex
- W2998570436
- Cited by
- 324
- References
- 2
- FWCI
- 13.12
- Type
- journal article
- Language
- en
- Open access
- gold
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- Yang, N., Xiao, W., Song, X., Wang, W., & Dong, X. (2020). Recent Advances in Tumor Microenvironment Hydrogen Peroxide-Responsive Materials for Cancer Photodynamic Therapy. Nano-Micro Letters. https://doi.org/10.1007/s40820-019-0347-0
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