A Review of the Application of Multi-modal Deep Learning in Medicine: Bibliometrics and Future Directions
Open accessAbstract
In recent years, deep learning has been applied in the field of clinical medicine to process large-scale medical images, for large-scale data screening, and in the diagnosis and efficacy evaluation of various major diseases. Multi-modal medical data fusion based on deep learning can effectively extract and integrate characteristic information of different modes, improve clinical applicability in diagnosis and medical evaluation, and provide quantitative analysis, real-time monitoring, and treatment planning. This study investigates the performance of existing multi-modal fusion pre-training algorithms and medical multi-modal fusion methods and compares their key characteristics, such as supported medical data, diseases, target samples, and implementation performance. Additionally, we present the main challenges and goals of the latest trends in multi-modal medical convergence. To provide a clearer perspective on new trends, we also analyzed relevant papers on the Web of Science. We obtain some meaningful results based on the annual development trends, country, institution, and journal-level research, highly cited papers, and research directions. Finally, we perform co-authorship analysis, co-citation analysis, co-occurrence analysis, and bibliographic coupling analysis using the VOSviewer software.
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No review has systematically summarized the methodologies and processes specific to the application of multimodal AI in critical care.
“However, to the best of our knowledge, no review has systematically summarized the methodologies and processes specific to the application of multimodal AI in critical care.”
From Multimodal Artificial Intelligence for Precision Critical Care: A Scoping Review (2026) · cites this paper as [22]
The Medical Imaging and Non-imaging Models and Conclusion passages discuss multimodal deep learning in medicine, but neither addresses whether a review of multimodal AI methodologies and processes in critical care exists. Searches for critical care, intensive care, and the claimed absence of a systematic review found no passage stating that point; the available passages have no page numbers. (LLM, conf=0.76)
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Cited by
Sorted by citations
Review of multimodal machine learning approaches in healthcare
Krones, F., Marikkar, U., Parsons, G., Szmul, A., & Mahdi, A. (2025) · Information Fusion · doi:10.1016/j.inffus.2024.102690 · Cited by 235 · see citing works
The role of multimodality in clinical disease diagnosis: advances, challenges, and opportunities
Nawaz, A., Edinat, A., Rana, M. R. R., Ali, T., Mustafa, G., Tahir, S., & Lee, S. W. (2026) · Frontiers in public health · doi:10.3389/fpubh.2026.1788454 · Cited by 3 · see citing works
Multimodal Artificial Intelligence for Precision Critical Care: A Scoping Review
Yang, M., Shi, N., Chen, H., Po, E. Y. P., Ng, P. Y., Lai, P. C. K., Wu, Y.-C., & Fong, D. Y. T. (2026) · Health Data Science · doi:10.34133/hds.0356 · Cited by 3 · see citing works
“Some previous reviews have provided broad overviews of multimodal AI in medicine or healthcare [ 7 , 8 , 16 , 17 , 22 ], and others have focused specifically on the integration of biomedical images and clinical EHR data [ 23 – 25 ] or domains such as oncology [ 26 , 27 ] and cancer biomarker…”
- Authors
- Pei, X., Zuo, K., Li, Y., & Pang, Z.
- Affiliations
- National University of Defense Technology (CN)
- Corresponding author
- Pang, Zhengbin
- Venue
- International Journal of Computational Intelligence Systems
- Published
- 2023-03-29
- Volume
- 16
- Issue
- 1
- ISSN
- 1875-6883 (ISSN-L)
- OpenAlex
- W4361284377
- Cited by
- 77
- References
- 8
- Citations by year
- 2026: 13 · 2025: 35 · 2024: 21 · 2023: 8
- FWCI
- 7.00
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- International Journal of Computational Intelligence Systems (publishedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- scientific research project of the Science and Technology Department of Shanxi Province (2020FP-11)
- Topics
- Physical Sciences › Computer Science › Computer Vision and Pattern Recognition › Multimodal Machine Learning Applications
- Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
- Physical Sciences › Engineering › Media Technology › Advanced Image Fusion Techniques
- Keywords
- multimodal deep learning, medical image analysis, diagnosis, treatment planning, research trends, bibliometric analysis, co-authorship analysis, co-citation analysis
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