Cited by 242Lipoproteins and Cardiovascular HealthCholesterol and Lipid MetabolismParaoxonase enzyme and polymorphisms

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High-density lipoproteins: Epidemiologic profile and risks of coronary artery disease

Kannel, William B.·1983·The American Journal of Cardiology

DOI 10.1016/0002-9149(83)90649-5

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Cholesterol in the Prediction of Atherosclerotic Disease
Kannel, W. B., Castelli, W. P., & Gordon, T. (1979) · Annals of Internal Medicine · doi:10.7326/0003-4819-90-1-85 · Cited by 1,314
Self-citation
Relationship of blood pressure, serum cholesterol, smoking habit, relative weight and ECG abnormalities to incidence of major coronary events: Final report of the pooling project
The Pooling Project Research Group (1978) · Journal of Chronic Diseases · doi:10.1016/0021-9681(78)90073-5 · Cited by 994
Lipoproteins, Cardiovascular Disease, and Death
Gordon, T. (1981) · Archives of Internal Medicine · doi:10.1001/archinte.1981.00340090024008 · Cited by 565

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“Importantly, residual risk remains even after achieving optimal LDL-C concentration with statins [5], probably due to other risk factors, such as high triglycerides, low high-density lipoprotein cholesterol (HDL-C) levels, defective glucose metabolism and other non-lipid-related risk factors [29-32].”
Background
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“The relationship between serum cholesterol and incidence of CVD become stronger when the number of risk factors was increased (Kannel, 1983).”
Background
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“These findings are consistent with the concept that the severity of atherosclerosis is determined, in part, by the level of hypercholesterolemia, as has been inferred from epidemiological studies for spontaneous lesions ( 25 , 26).”
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“고혈압, 흡연과 함께 특히 혈중 지질인 총 콜레스테롤과 중성지방의 상승이 동 맥경화증과 관상동맥질환의 직접적 원인이며 콜레스테롤 은 가장 큰 영향을 미친다고 하였다(Kannel, 1983; Castelli et al, 1984; Gordon et al, 1997).”
The Epidemiology of Coronary Artery Disease
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“architectures to nudge crowds to collectively advance their high density lipoprotein level (HDL) by 10 mg/dl, the crowd cardiovascular event rate would decline by 50% [72-76].”
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Impact of lipid‐lowering therapy on the prevalence of dyslipidaemia in patients at high‐risk of cardiovascular events in UK primary care – a retrospective database study
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“Correlations between serum cholesterol levels and progression of coronary and peripheral atherosclerosis have been found in many recent studies (2-7).”
Background
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Kłosiewicz−Latoszek, L., Nowicka, G., Szostak, W. B., & Naruszewicz, M. (1987) · Atherosclerosis · doi:10.1016/0021-9150(87)90122-5 · Cited by 11
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“Indeed, coronary artery disease is highly influenced by cholesterol.(8) It has also been reported that regular and persistent aerobic exercise dissolves TG in the blood by activating lipoprotein catalysts and positively influences the prevention of and therapy in cardiovascular disease, such as hyperlipidemia, decreas…”
Background
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“Within a short time, thanks also to the results obtained with the first extensive lipidologic trials, there was increasing evidence of a strong association between low HDL levels and cardiovascular disease [7–12].”
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Coronary heart disease in women
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Lipoprotein Analysis in the Evaluation of Chest Pain in the Emergency Department
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Is high-density lipoprotein a modifiable treatment target or just a biomarker for cardiovascular disease?
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“Source: Modified with permission from Kannel.(9) CHD: coronary heart disease; HDL-C: high-density lipoprotein cholesterol.”
Background
Coronary heart disease: How do the benefits of ω‐3 fatty acids compare with those of aspirin, alcohol/red wine, and statin drugs?
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“Every change of 10 mg/dL in the HDL-C level is associated with a 50% change in risk (based on the elderly cohort of the Framingham Heart Study).(10) For every 1 mg/dL increase in HDL-C, there is a 2% decrease in risk of CHD in men and a 3% decrease in women, according to one meta-analysis.”
Background
CLUSTERING OF CARDIOVASCULAR RISK FACTORS IN DIABETICS AND IGT CASES IN ISFAHAN PROVINCE 2000-2001: ISFAHAN HEALTHY HEART PROGRAM
Sajjadi, F., Mohammadifard, N., Ghaderian, N., Alikhasi, H., & Maghroon, M. (2010) · DOAJ (DOAJ: Directory of Open Access Journals) · Cited by 5
High-Density Lipoproteins
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“[7] The lipid-atherogenesis connection has undergone a major change from an initial focus on serum total cholesterol, later on the other lipids and then on the lipoproteins that transport them, and now on the distribution of cholesterol in the LDLs, HDLs, and VLDLs.[8] Elevated serum LDL and VLDL cholesterol, and low…”
Background
¿Era necesario demostrar también en España que la colesterolemia y el tabaco son factores de riesgo cardiovascular?
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Total and high-density lipoprotein cholesterol measurements. Hazards in clinical interpretation.
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High-Density Lipoprotein Cholesterol
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Management of the patient with a low HDL‐cholesterol
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Crossover point and maximal fat oxidation training effects on blood lipid metabolism in young overweight women: a pilot study
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“Multiple epidemiological studies have shown that higher serum TC levels are associated with greater coronary heart disease risk (Kannel, 1983).”
Background
Epidemic of the Century: Metabolic Syndrome
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“Recent research has identified other important risk factors that may help identify patients at risk for a first MI (Figure 1, Table I).(2,40) Not all of these have current clinical usefulness.”
Background
Lipid-Sensing High-Throughput ApoA-I Assays
Niedziela‐Majka, A., Lad, L., Chisholm, J. W., Lagpacan, L., Schwartz, K., Hung, M., Jin, D., Fung, W., Brendza, K. M., Liu, X., et al. (2012) · SLAS DISCOVERY · doi:10.1177/1087057112451923 · Cited by 3
“In humans, low HDL is a risk factor for the development of cardiovascular disease (CVD).(5,6) Numerous studies using knockout and transgenic mouse models, studies of patients with Tangiers disease (natural genetic ABCA1 knockout), and clinical association studies have validated ABCA1 as a critical transporter in the f…”
Background
Forensic Aspects of Adult and General Neuropathology
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Minimization of Intraparenchymal Hemorrhagic Stroke Size by Optimization of Serum Lipids
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Cardiovascular Risk Assessment in Hypertension
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Interrelation between risk factors for cardiovascular disease in men aged 33–42: A study from Habo in Skaraborg County, Sweden
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Background
The role of phospholipid transfer protein and cholesteryl ester transfer protein in reverse cholesterol transport
Vikstedt, R. (2009) · STM:n Hallinnonalan avoin julkaisuarkisto (Julkari)

Authors: Kannel, W. B.
Affiliations: Boston University (US)
Corresponding author: Kannel, William B.
Venue: The American Journal of Cardiology
Publisher: Elsevier BV
Published: 1983-08
Volume: 52
Issue: 4
Pages: B9-B12
ISSN: 0002-9149 (ISSN-L)
DOI: 10.1016/0002-9149(83)90649-5
OpenAlex: W2084240983
Cited by: 242
References: 3
Citations by year: 2026: 1 · 2024: 1 · 2023: 2 · 2022: 1 · 2021: 1 · 2020: 1 · 2019: 3 · 2018: 3 · 2017: 1 · 2016: 4 · 2015: 4 · 2014: 7 · 2013: 5 · 2012: 12
FWCI: 8.67
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: The American Journal of Cardiology (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipoproteins and Cardiovascular Health
Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Cholesterol and Lipid Metabolism
Life Sciences › Biochemistry, Genetics and Molecular Biology › Clinical Biochemistry › Paraoxonase enzyme and polymorphisms
Keywords: high-density lipoprotein, HDL cholesterol, coronary artery disease, LDL cholesterol, LDL/HDL ratio, total cholesterol, atherogenesis, lipoprotein subfractions, apolipoproteins, stroke, peripheral arterial disease, colon cancer, cardiovascular risk
MeSH terms: Cholesterol, Coronary Disease, Humans, Lipoproteins, HDL, Cholesterol, HDL, Lipoproteins, LDL, Cholesterol, LDL, Lipoproteins, VLDL, Risk, Triglycerides, Cholesterol, VLDL

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High-density lipoproteins: Epidemiologic profile and risks of coronary artery disease

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