The DOI matches its Crossref record; 39 of the 39 references it cites were found in a registry or an index.
Common symptoms in ambulatory care: Incidence, evaluation, therapy, and outcome
Abstract
Purpose and patients and methods Many symptoms in outpatient practice are poorly understood. To determine the incidence, diagnostic findings, and outcome of 14 common symptoms, we reviewed the records of 1,000 patients followed by house staff in an internal medicine clinic over a three-year period. The following data were abstracted for each symptom: patient characteristics, symptom duration, evaluation, suspected etiology of the symptom, treatment prescribed, and outcome of the symptom. Cost estimates for diagnostic evaluation were calculated by means of the schedule of prevailing rates for Texas employed by the Civilian Health and Medical Program of the Uniformed Services for physician reimbursement.Results A total of 567 new complaints of chest pain, fatigue, dizziness, headache, edema, back pain, dyspnea, insomnia, abdominal pain, numbness, impotence, weight loss, cough, and constipation were noted, with 38 percent of the patients reporting at least one symptom. Although diagnostic testing was performed in more than two thirds of the cases, an organic etiology was demonstrated in only 16 percent. The cost of discovering an organic diagnosis was high, particularly for certain symptoms, such as headache ($7,778) and back pain ($7,263). Treatment was provided for only 55 percent of the symptoms and was often ineffective. Where outcome was documented, 164 (53 percent) of 307 symptoms improved. Three favorable prognostic factors were an organic etiology (p = 0.006), a symptom duration of less than four months (p = 0.009), and a history of two or fewer symptoms (p = 0.001).Conclusion The classification, evaluation, and management of common symptoms need to be refined. Diagnostic strategies emphasizing organic causes may be inadequate.
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In the citing paper
“One study discovered that 84 % of 567 common complaints, such as dizziness and chest pain, indicated no medical diagnosis [9].”
From Consequences of Repression of Emotion: Physical Health, Mental Health and General Well Being (2019) · cites this paper as [9]
In the citing paper
“Of note is the fact that in most of these patients, a DSM-IV diagnosis of psychiatric disease is not present; Kroenke and Mangelsdorff [3] found that only 10% of patients with the undiagnosed symptoms had an overt psychiatric illness.”
From Treatment of somatization in primary care (1997) · cites this paper as [3]
In the citing paper
“In a study by Kroenke and Mangelsdorff [3], only 1 in 10 patients reporting 14 of the most common physical symptoms in primary care had an organic diagnosis even after extensive and costly testing.”
From Treatment of somatization in primary care (1997) · cites this paper as [3]
Citations
Cites
The Need for a New Medical Model: A Challenge for Biomedicine
Engel, G. L. (1977) · Science · doi:10.1126/science.847460 · Cited by 12,887
Diagnostic and Statistical Manual of Mental Disorders
&NA; (1988) · Alzheimer Disease & Associated Disorders · doi:10.1097/00002093-198802020-00022 · Cited by 12,603
The Hopkins Symptom Checklist (HSCL): A self-report symptom inventory
Derogatis, L. R., Lipman, R. S., Rickels, K., Uhlenhuth, E. H., & Covi, L. (1974) · Behavioral Science · doi:10.1002/bs.3830190102 · Cited by 4,604
Chronic Fatigue in Primary Care
Kroenke, K. (1988) · JAMA · doi:10.1001/jama.260.7.929 · Cited by 558
Depression and somatization: a review
Katon, W. J., Kleinman, A., & Rosen, G. (1982) · The American Journal of Medicine · doi:10.1016/0002-9343(82)90816-6 · Cited by 530
Depression and somatization: a review
Katon, W. J., Kleinman, A., & Rosen, G. (1982) · The American Journal of Medicine · doi:10.1016/0002-9343(82)90599-x · Cited by 419
Some preliminary findings on physical complaints from a prospective study of 1,064,004 men and women
Hammond, E. C. (1964) · American Journal of Public Health and the Nations Health · doi:10.2105/ajph.54.1.11 · Cited by 401
Scientific and Clinical Problems in Indexes of Functional Disability
Feinstein, A. R., JOSEPHY, B. R., & WELLS, C. K. (1986) · Annals of Internal Medicine · doi:10.7326/0003-4819-105-3-413 · Cited by 395
An Additional Basic Science for Clinical Medicine: IV. The Development of Clinimetrics
Feinstein, A. R. (1983) · Annals of Internal Medicine · doi:10.7326/0003-4819-99-6-843 · Cited by 258
Verbrugge, L. M., & Ascione, F. J. (1987) · Medical Care · doi:10.1097/00005650-198706000-00008 · Cited by 257
Research works printed but not linked: 1
- Gordon, 1987, Treating somatizing patients, West J Med, 147, 88
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Sorted by citations
The PHQ-15: Validity of a New Measure for Evaluating the Severity of Somatic Symptoms
Kroenke, K., Spitzer, R. L., & Williams, J. B. W. (2002) · Psychosomatic Medicine · doi:10.1097/00006842-200203000-00008 · Cited by 3,415
The functional gastrointestinal disorders and the Rome III process
Drossman, D. A. (2006) · Gastroenterology · doi:10.1053/j.gastro.2006.03.008 · Cited by 2,416
The Development and Psychometric Validation of the Central Sensitization Inventory
Mayer, T. G., Neblett, R., Cohen, H. M., Howard, K. J., Choi, Y. H., Williams, M. J., Perez, Y., & Gatchel, R. J. (2011) · Pain Practice · doi:10.1111/j.1533-2500.2011.00493.x · Cited by 1,017
BARSKY, A. J., Orav, E. J., & Bates, D. W. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.8.903 · Cited by 912
Somatic symptom reporting in women and men
Barsky, A. J., Peekna, H. M., & Borus, J. F. (2001) · Journal of General Internal Medicine · doi:10.1046/j.1525-1497.2001.016004266.x · Cited by 816
Metadata
- Authors
- Kroenke, K., & Mangelsdorff, A. D.
- Affiliations
- Uniformed Services University of the Health Sciences (US)
- Brooke Army Medical Center (US)
- ORCID
- Kroenke, Kurt
- Venue
- The American Journal of Medicine
- Publisher
- Elsevier BV
- Published
- 1989-03
- Volume
- 86
- Issue
- 3
- Pages
- 262-266
- ISSN
- 0002-9343 (ISSN-L)
- OpenAlex
- W1984623074
- Cited by
- 947
- References
- 39
- Citations by year
- 2026: 9 · 2025: 17 · 2024: 12 · 2023: 13 · 2022: 14 · 2021: 11 · 2020: 18 · 2019: 20 · 2018: 20 · 2017: 25 · 2016: 23 · 2015: 25 · 2014: 39 · 2013: 31 · 2012: 32
- FWCI
- 36.80
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The American Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Family Practice › Primary Care and Health Outcomes
- Health Sciences › Medicine › Family Practice › Clinical Reasoning and Diagnostic Skills
- Health Sciences › Medicine › Epidemiology › Chronic Disease Management Strategies
- Keywords
- common symptoms, outpatient care, symptom incidence, diagnostic assessment, treatment outcomes, organic etiology, diagnostic costs, symptom duration, prognostic factors, headache, back pain, chest pain, fatigue, dizziness, dyspnea, abdominal pain, cough, constipation, weight loss, insomnia, internal medicine clinic
- MeSH terms
- Ambulatory Care, Diagnosis, Disease, Female, Humans, Male, Military Personnel, Morbidity, Prognosis, Retrospective Studies
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