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Cited by 1,686Atrial Fibrillation Management and OutcomesCardiac tumors and thrombiCardiovascular and Diving-Related Complications

The DOI matches its Crossref record; 59 of the 61 references it cites were found in a registry or an index.

Appendage obliteration to reduce stroke in cardiac surgical patients with atrial fibrillation

Blackshear, Joseph L., Odell, John A.·1996·The Annals of Thoracic Surgery
DOI 10.1016/0003-4975(95)00887-x
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Abstract

Background Left atrial appendage obliteration was historically ineffective for the prevention of postoperative stroke in patients with rheumatic atrial fibrillation who underwent operative mitral valvotomy. It is, however, a routine part of modern "curative" operations for nonrheumatic atrial fibrillation, such as the maze and corridor procedures.Methods To assess the potential of left atrial appendage obliteration to prevent stroke in nonrheumatic atrial fibrillation patients, we reviewed previous reports that identified the etiology of atrial fibrillation and evaluated the presence and location of left atrial thrombus by transesophageal echocardiography, autopsy, or operation.Results Twenty-three separate studies were reviewed, and 446 of 3,504 (13%) rheumatic atrial fibrillation patients, and 222 of 1,288 (17%) nonrheumatic atrial fibrillation patients had a documented left atrial thrombus. Anticoagulation status was variable and not controlled for. Thrombi were localized to, or were present in the left atrial appendage and extended into the left atrial cavity in 254 of 446 (57%) of patients with rheumatic atrial fibrillation. In contrast, 201 of 222 (91%) of nonrheumatic atrial fibrillation-related left atrial thrombi were isolated to, or originated in the left atrial appendage (p < 0.0001).Conclusions These data suggest that left atrial appendage obliteration is a strategy of potential value for stroke prophylaxis in nonrheumatic atrial fibrillation.

Overview

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Crossref · 10.1016/0003-4975(95)00887-x

Cites

59 of 59 references verified0 citation errors · 0 not checkable

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Citations

Cites

Show all 61 references

Research works printed but not linked: 8

  1. Manning, 1994, Sensitivity and specificity of transesophageal echo for left atrial thrombi: a prospective, consecutive surgical study, Circulation, 90, 1202a
  2. Manning, 1994, Transesophageal echo (TEE) facilitated early cardioversion for patients with new atrial fibrillation: a 4-year experience, Circulation, 90, I
  3. Cormier, 1991, Detection of thrombosis of the left atrium in mitral valve stenosis, Arch Maladies Coeur Vaisseaux, 84, 1321
  4. Klein, 1994, Assessment of cardioversion using transesophageal echocardiography compared to conventional therapy: The ACUTE Randomized Pilot Study, Circulation, 90, 21a
  5. Kanter, 1994, Carotid stenosis in patients with atrial fibrillation, Arch Intern Med, 154, 1372, 10.1001/archinte.1994.00420120100011 · DOI
  6. Labovitz, 1994, Transesophageal echocardiography in patients with unexplained cerebral ischemia: multicenter findings, Circulation, 90, I
  7. Mugge, 1990, Diagnosis of left atrial appendage thrombi by transesophageal echocardiography: clinical implications and follow-up, Am J Cardiol Imaging, 4, 173
  8. Davila-Roman, 1994, Artherosclerosis of the ascending aorta, Stroke, 25, 2010

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Metadata

Authors
Blackshear, J. L., & Odell, J. A.
Affiliations
Mayo Clinic (US)
Venue
The Annals of Thoracic Surgery
Publisher
Elsevier BV
Published
1996-02
Volume
61
Issue
2
Pages
755-759
ISSN
0003-4975 (ISSN-L)
DOI
10.1016/0003-4975(95)00887-x
OpenAlex
W2053482681
Cited by
1,686
References
61
Citations by year
2026: 78 · 2025: 68 · 2024: 98 · 2023: 112 · 2022: 93 · 2021: 108 · 2020: 126 · 2019: 100 · 2018: 111 · 2017: 121 · 2016: 100 · 2015: 125 · 2014: 81 · 2013: 75 · 2012: 61
FWCI
0.91
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • The Annals of Thoracic Surgery (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac tumors and thrombi
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Cardiovascular and Diving-Related Complications
Keywords
atrial fibrillation, postoperative stroke, stroke prevention, left atrial thrombus, non-valvular atrial fibrillation, cardiac surgery, mitral valve surgery, maze procedure, anticoagulation
MeSH terms
Contraindications, Aged, Atrial Fibrillation, Cerebrovascular Disorders, Heart Atria, Heart Diseases, Humans, Mitral Valve Stenosis, Postoperative Complications, Thrombosis, Warfarin

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