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Glutamine synthetase
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Glutamine is a critical amino acid involved in energy metabolism and extracellular matrix formation and has been identified as a key regulator of liver regeneration.
“Glutamine (Gln), a critical amino acid, involved in energy metabolism and ECM formation, has been also identified as a key regulator of LR[71].”
From Liver regeneration after partial hepatectomy: Triggers and mechanisms (2025) · cites this paper as [71]
The Results (page unavailable) examine glutamine synthetase activity during rat liver regeneration and report that free glutamine levels in regenerating liver were not significantly different from normal liver. The paper does not establish that glutamine regulates liver regeneration or describe its roles in energy metabolism or extracellular matrix formation; searches for those roles found no supporting passage. (LLM, conf=0.76)
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Cited by
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Liver regeneration after partial hepatectomy: Triggers and mechanisms
Korchilava, B., Khachidze, T., Megrelishvili, N., Svanadze, L., Kakabadze, M., Tsomaia, K., Jintcharadze, M., & Kordzaia, D. (2025) · World Journal of Hepatology · doi:10.4254/wjh.v17.i7.107378 · Cited by 21
Metadata
- Authors
- Wu, C.
- Affiliations
- University of Michigan (US)
- Corresponding author
- Wu, Chung
- ORCID
- Wu, Chung
- Venue
- Archives of Biochemistry and Biophysics
- Publisher
- Elsevier BV
- Published
- 1964
- Volume
- 106
- Pages
- 402-409
- ISSN
- 0003-9861 (ISSN-L)
- OpenAlex
- W1484399243
- Cited by
- 19
- References
- 0
- Citations by year
- 2025: 1 · 2020: 1 · 2013: 2
- FWCI
- 0.14
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Locations
- Archives of Biochemistry and Biophysics (publishedVersion)
- PubMed (publishedVersion)
- Deep Blue (University of Michigan) (submittedVersion)
- Funders
- National Cancer Institute
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Amino Acid Enzymes and Metabolism
- Health Sciences › Medicine › Hepatology › Liver physiology and pathology
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Biochemical and Molecular Research
- Keywords
- glutamine synthetase, partial hepatectomy, liver regeneration, mitotic growth, fasting and refeeding, dietary protein, nephrectomy, protein-free diet, enzyme synthesis, rats
- MeSH terms
- Brain, Caseins, Dietary Proteins, DNA, Fasting, Glutamine, Glutamate-Ammonia Ligase, Hepatectomy, Humans, Kidney, Ligases, Liver, Liver Diseases, Liver Regeneration, Male, Nephrectomy, Research, Testis, Rats
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