Appetite and food preference in depression: effects of imipramine treatment
Abstract
A nutritional survey, the Pittsburgh Appetite Test (PAT), was developed to study potential changes in appetite and food preference reported by patients during a depressive episode and during antidepressant treatment. We examined a group of 50 depressed outpatients who were drug-free for 2 weeks prior to treatment with imipramine and psychotherapy for 4 months. A significant increase in the desire for "sweets" (carbohydrate--fat-rich foods) was observed during a depressive episode, compared to periods when patients recalled feeling well (retrospective data). During imipramine treatment, no further changes were observed in preference for either "sweets" or carbohydrates when compared to the medication-free period. Alterations in patient self-reports of appetite and body weight change were noted during imipramine treatment.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Perceived stress, hunger, and appetite were assessed using validated scales.
“Perceived stress, hunger, and appetite were assessed at hourly intervals by validated scales.”
From Adverse effects of two nights of sleep restriction on the hypothalamic-pituitary-adrenal axis in healthy men (2014) · cites this paper as [26]
The citation lists haven’t been fetched yet
References 18 · Cited by 90
- Authors
- Fernstrom, M. H., Krowinski, R. L., & Kupfer, D. J.
- Affiliations
- University of Pittsburgh (US)
- Corresponding author
- Fernstrom, Madelyn H.
- ORCID
- Kupfer, David J.
- Venue
- Biological Psychiatry
- Publisher
- Elsevier BV
- Published
- 1987-05
- Volume
- 22
- Issue
- 5
- Pages
- 529-539
- ISSN
- 0006-3223 (ISSN-L)
- OpenAlex
- W1985678766
- Cited by
- 90
- References
- 18
- Citations by year
- 2025: 5 · 2024: 2 · 2021: 3 · 2019: 1 · 2018: 2 · 2017: 2 · 2016: 2 · 2015: 3 · 2014: 4 · 2013: 3 · 2012: 1
- FWCI
- 6.76
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Biological Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Mental Health (MH 29618, MH30915)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Health Sciences › Nursing › Nutrition and Dietetics › Nutrition, Health and Food Behavior
- Keywords
- depression, appetite, food preferences, imipramine, antidepressant treatment, carbohydric foods, sweets, weight change, nutritional surveys, psychotherapy
- MeSH terms
- Adult, Appetite, Body Weight, Depressive Disorder, Female, Food Preferences, Humans, Imipramine, Male, Middle Aged
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
