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CSF isatin is elevated in bulimia nervosa
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“Interestingly, isatin is detectable in a range of host tissues, including human cerebral spinal fluid and the hippocampus (Medvedev et al., 2007), and has been shown to be elevated in patients diagnosed with bulimia nervosa (Brewerton et al., 1995).”
From The Microbiota-Gut-Brain Axis (2019) · cites this paper as Brewerton et al., 1995
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Research works printed but not linked: 24
- Armando, 1986, Distribution of endogenous benzodiazepine receptor ligand-monoamine oxidase inhibitory activity (tribulin) in tissues, Life Sci, 38, 2063, 10.1016/0024-3205(86)90155-4 · DOI
- Armando, 1983, Output of endogenous monoamine oxidase inhibitor in rats: effect of ethanol, tryptamine and tryptophan, J Neural Transm, 56, 85, 10.1007/BF01243376 · DOI
- Beck, 1961, An inventory for measuring depression, Arch Gen Psychiatry, 4, 561, 10.1001/archpsyc.1961.01710120031004 · DOI · Paper page
- Bhattacharya, 1993, Further investigations on the anxiogenic effects of isatin, Biogenic Amines, 9, 453
- Bhattacharya, 1991, Effect of aromatic amino acids, pentylenetetrazole and yohimbine on isatin and tribulin activity in rat brain, Neurosci Lett, 132, 44, 10.1016/0304-3940(91)90429-W · DOI
- Bhattacharya, 1988, Stress causes an increase in endogenous monoamine oxidase inhibitor (tribulin) in rat brain, Neurosci Lett, 92, 218, 10.1016/0304-3940(88)90064-X · DOI
- Bhattacharya, 1982, Raised endogenous monoamine oxidase inhibitor output in postwithdrawal alcoholics: effects of L-dopa and ethanol, Biol Psychiatry, 17, 829
- Bhattacharya, 1991, Anxiogenic activity of isatin, a putative biological factor, in rodents, J Psychopharmacol, 5, 202, 10.1177/026988119100500304 · DOI
- Brewerton, 1992, CSF Beta-endorphin and dynorphin in bulimia nervosa, Am J Psychiatry, 149, 1086, 10.1176/ajp.149.8.1086 · DOI
- Clow, 1989, Isatin and tribulin concentrations are increased in rabbit brain but not liver following pentylenetetrazole administration, Neurosci Lett, 107, 327, 10.1016/0304-3940(89)90840-9 · DOI
- Clow, 1983, New endogenous benzodiazepine receptor ligand in human tissue: identity with endogenous monoamine oxidase inhibitor?, Life Sci, 33, 735, 10.1016/0024-3205(83)90778-6 · DOI
- Elsworth, 1986, Purification and characterization of tribulin, an endogenous inhibitor of monoamine oxidase and of benzodiazepine receptor binding, J Neural Transm, 67, 45, 10.1007/BF01243358 · DOI
- Garner, 1982, The Eating Attidues Test: psychometric features and clinical correlates, Psychol Med, 12, 871, 10.1017/S0033291700049163 · DOI
- Glover, 1981, Benzodiazepines reduce stress-augmented increase in rat urine monoamine oxidase inhibitor, Nature, 292, 347, 10.1038/292347a0 · DOI
- Glover, 1988, Isatin: Identity with the purified endogenous monoamine oxidase inhibitor tribulin, J Neurochem, 51, 656, 10.1111/j.1471-4159.1988.tb01089.x · DOI
- Glover, 1980, A monoamine oxidase inhibitor in human urine, Biochem Pharmacol, 29, 467, 10.1016/0006-2952(80)90534-1 · DOI
- Halket, 1991, Isatin (indole-2,3-dione) in urine and tissues, J Chromatogr, 562, 279, 10.1016/0378-4347(91)80585-Z · DOI
- Hamilton, 1960, A rating scale for depression, J Neurol Neurosurg Psychiatry, 6, 278
- Hamilton, 1959, The assessment of anxiety states by rating, Br J Med Psychology, 32, 50, 10.1111/j.2044-8341.1959.tb00467.x · DOI · Paper page
- Lydiard, 1993, CSF cholecystokinin octapeptide in bulimia nervosa, Am J Psychiatry, 150, 1099, 10.1176/ajp.150.7.1099 · DOI
- Petursson, 1982, Urinary monoamine oxidase inhibitor and benzodiazepine withdrawal, Br J Psychiatry, 140, 7, 10.1192/bjp.140.1.7 · DOI
- Petursson, 1981, Urinary MAO inhibitor in psychiatric illness, Psychiatry Res, 5, 335, 10.1016/0165-1781(81)90081-0 · DOI
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Cited by
Sorted by citations
Cryan, J. F., O'Riordan, K. J., Cowan, C. S. M., Sandhu, K. V., Bastiaanssen, T. F. S., Boehme, M., Codagnone, M. G., Cussotto, S., Fulling, C., Golubeva, A. V., et al. (2019) · Physiological Reviews · doi:10.1152/physrev.00018.2018 · Cited by 5,286
Metadata
- Authors
- Brewerton, T. D., Zealberg, J. J., Lydiard, R. B., Glover, V., Sandler, M., & Ballenger, J. C.
- Affiliations
- Medical University of South Carolina (US)
- Queen Charlotte's and Chelsea Hospital (GB)
- Corresponding author
- Brewerton, Timothy D.
- Venue
- Biological Psychiatry
- Publisher
- Elsevier BV
- Published
- 1995-04
- Volume
- 37
- Issue
- 7
- Pages
- 481-483
- ISSN
- 0006-3223 (ISSN-L)
- OpenAlex
- W2029717302
- Cited by
- 24
- References
- 0
- Citations by year
- 2024: 2 · 2022: 1 · 2020: 2 · 2019: 1 · 2013: 2
- FWCI
- 3.48
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Biological Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
- Life Sciences › Neuroscience › Biological Psychiatry › Tryptophan and brain disorders
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
- Keywords
- isatin, bulimia nervosa, cerebrospinal fluid, monoamine oxidase B inhibition, benzodiazepine binding, anxiety, stress
- MeSH terms
- Adult, Anxiety, Arousal, Bulimia, Depression, Female, Humans, Isatin, Life Change Events, Male, Personality Inventory, Reference Values
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- CoChat. (2026). Citation check: CSF isatin is elevated in bulimia nervosa. https://app.cochat.ai/papers/10.1016/0006-3223(94)00328-z
- The paper
- Brewerton, T. D., Zealberg, J. J., Lydiard, R. B., Glover, V., Sandler, M., & Ballenger, J. C. (1995). CSF isatin is elevated in bulimia nervosa. Biological Psychiatry. https://doi.org/10.1016/0006-3223(94)00328-z