Disulfiram inhibition of development of tolerance to analgesia induced by central gray stimulation in humans
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
DIS was shown to produce clinically relevant enhancement of stimulation-induced analgesia in refractory pain patients that was insensitive to the development of tolerance for a period of 10 months.
“The hypothesis on DIS potential to abrogate morphine tolerance is related to the off-label drug use, as DIS was shown to produce clinically relevant enhancement of stimulation-induced analgesia in refractory pain patients that was insensitive to the development of tolerance for a period of 10 months.129”
From Off-label and repurposed use of disulfiram beyond alcohol dependence: A systematic review of clinical and preclinical evidence (2026) · cites this paper as [129]
The citation lists haven’t been fetched yet
References 4 · Cited by 33
- Authors
- Hosobuchi, Y., & Wemmer, J.
- Affiliations
- University of California, San Francisco (US)
- Corresponding author
- Hosobuchi, Y.
- Venue
- European Journal of Pharmacology
- Publisher
- Elsevier BV
- Published
- 1977-06
- Volume
- 43
- Issue
- 4
- Pages
- 385-387
- ISSN
- 0014-2999 (ISSN-L)
- OpenAlex
- W2061959860
- Cited by
- 33
- References
- 4
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 1 · 2022: 1 · 2021: 1 · 2013: 1 · 2012: 1
- FWCI
- 3.21
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- European Journal of Pharmacology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Pain Mechanisms and Treatments
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Keywords
- disulfiram, analgesic tolerance, periaqueductal gray, brain stimulation, analgesia, opioid tolerance
- MeSH terms
- Adult, Analgesia, Brain, Depression, Chemical, Disulfiram, Double-Blind Method, Electric Stimulation, Electrodes, Implanted, Female, Humans, Male, Middle Aged, Time Factors
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
