The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.
The biochemical modes of action of vitamin e and selenium: A hypothesis
Abstract
In this paper recent experimental work on rat liver is discussed which is considered to indicate that a primary function of vitamin E in vivo may be to inhibit the oxidation of selenide‐containing proteins present in mitochondria and in smooth endoplasmic reticulum. On the basis of molecular model building studies, it is also suggested that the well‐known nutritional relationships between vitamin E and dietary polyunsaturated lipids may be due to the occurrence within normal membranes of specific complexes between the vitamin and some of the molecules of polyunsaturated phospholipids. Without the vitamin, membranes may have an abnormally high permeability and they may be subject to degradation by endogenous phospholipases in vivo, as well as being abnormally susceptible to damage in vitro by dialuric acid and hydrogen peroxide.
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Citations
Cites
Asymmetrical Lipid Bilayer Structure for Biological Membranes
BRETSCHER, M. S. (1972) · Nature New Biology · doi:10.1038/newbio236011a0 · Cited by 652
Vitamin E as the Biological Lipid Antioxidant
Tappel, A. L. (1962) · Vitamins & Hormones · doi:10.1016/s0083-6729(08)60732-3 · Cited by 577
Vandenheuvel, F. A. (1963) · Journal of the American Oil Chemists' Society · doi:10.1007/bf02632843 · Cited by 267
Induction of Cellular DNA Synthesis in Human Leucocytes by Epstein–Barr Virus
Gerber, P. J., & Hoyer, B. H. (1971) · Nature · doi:10.1038/231046a0 · Cited by 261
Fat-Soluble Vitamins and Biological Membranes
Lucy, J. A., & Dingle, J. T. (1964) · Nature · doi:10.1038/204156a0 · Cited by 184
Self-citationDietary Control of Selenium Volatilization in the Rat
Ganther, H. E., Levander, O. A., & Baumann, C. A. (1966) · Journal of Nutrition · doi:10.1093/jn/88.1.55 · Cited by 128
Enzymic Synthesis of Dimethyl Selenide from Sodium Selenite in Mouse Liver Extracts*
Ganther, H. E. (1966) · Biochemistry · doi:10.1021/bi00867a039 · Cited by 120
Orme‐Johnson, W. H., & Beinert, H. (1969) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(69)90289-7 · Cited by 105
Identification of a phospholipase A1 in plasma membranes of rat liver
Newkirk, J. D., & Waite, M. (1971) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(71)90215-x · Cited by 88
HEMOLYSIS WITH ALLOXAN AND ALLOXAN-LIKE COMPOUNDS, AND THE PROTECTIVE ACTION OF TOCOPHEROL
Rose, C. S., & György, P. (1950) · Blood · doi:10.1182/blood.v5.11.1062.1062 · Cited by 84
Cited by
Tocopherols and tocotrienols in membranes: A critical review
Atkinson, J., Epand, R. F., & Epand, R. M. (2008) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2007.11.010 · Cited by 287
The fusion of erythrocytes by fatty acids, esters, retinol and α-tocopherol
Ahkong, Q. F., Fisher, D., Tampion, W., & Lucy, J. A. (1973) · Biochemical Journal · doi:10.1042/bj1360147 · Cited by 284
Self-citationBurke, K. E., Clive, J., Combs, G. F., Commisso, J., Keen, C. L., & Nakamura, R. M. (2000) · Nutrition and Cancer · doi:10.1207/s15327914nc381_13 · Cited by 108
Schmidt, M. C., Askew, E. W., Roberts, D. E., Prior, R. L., Ensign Jr, W. Y., & Hesslink Jr, R. E. (2002) · Wilderness & Environmental Medicine · doi:10.1580/1080-6032(2002)013[0094:osihti]2.0.co;2 · Cited by 97
Metadata
- Authors
- Diplock, A. T., & Lucy, J. A.
- Venue
- FEBS Letters
- Publisher
- Wiley
- Published
- 1973-02
- Volume
- 29
- Issue
- 3
- Pages
- 205-210
- ISSN
- 0014-5793 (ISSN-L)
- 1873-3468
- OpenAlex
- W2013887768
- Cited by
- 310
- References
- 14
- FWCI
- 12.16
- Type
- journal article
- Language
- en
- Open access
- closed
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Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
