The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.
Induction of nitric oxide synthase by cytokines in vascular smooth muscle cells
Open accessAbstract
We investigated the mechanisms by which cytokines lead to a diminished responsiveness of vascular smooth muscle to vasoconstrictors. The attenuation of noradrenaline‐induced contraction by 6 to 24 h incubations with the cytokines, tumor necrosis factor and interleukin‐1, in endotheliumdenuded rabbi, aorta was associated with an increase in intracellular cyclic GMP level. This increase was abolished by the stereoselective inhibitor of nitric oxide‐synthase. N o‐nitro‐L‐arginine and by cycloheximide. Formation of nitric oxide was detected in the cytosol of cytokine‐treated native and cultured smooth muscle cells by activation of purified soluble guanylate cyclase, and depended on tetrahydrobiopterin, but not on ? ‐calmodulin. The results indicate that cytokines induce a nitric oxide‐synthase of the macrophage‐type in vascular smooth muscle.
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Cites
Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids
Green, L. C., Wagner, D. A., Glogowski, J., Skipper, P. L., Wishnok, J. S., & Tannenbaum, S. R. (1982) · Analytical Biochemistry · doi:10.1016/0003-2697(82)90118-x · Cited by 12,077
Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia
Tracey, K. J., Fong, Y., Hesse, D. G., Manogue, K. R., Lee, A. T., Kuo, G. C., Lowry, S. F., & Cerami, A. (1987) · Nature · doi:10.1038/330662a0 · Cited by 2,448
Macrophage oxidation of L-arginine to nitrite and nitrate: nitric oxide is an intermediate
Marletta, M. A., Yoon, P. S., Iyengar, R., Leaf, C. D., & Wishnok, J. S. (1988) · Biochemistry · doi:10.1021/bi00424a003 · Cited by 1,600
Biosynthesis of nitric oxide from l-arginine
Moncada, S., Palmer, R. M. J., & Higgs, E. A. (1989) · Biochemical Pharmacology · doi:10.1016/0006-2952(89)90403-6 · Cited by 1,208
Kilbourn, R. G., Gross, S. S., Jubran, A., Adams, J., Griffith, O. W., Levi, R., & Lodato, R. F. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.9.3629 · Cited by 650
Calcium‐dependent nitric oxide synthesis in endothelial cytosol is mediated by calmodulin
Busse, R., & Mülsch, A. (1990) · FEBS Letters · doi:10.1016/0014-5793(90)80902-u · Cited by 511
Self-citationKilbourn, R. G., & Belloni, P. (1990) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/82.9.772 · Cited by 465
Nitric oxide: biosynthesis and biological significance
Marletta, M. A. (1989) · Trends in Biochemical Sciences · doi:10.1016/0968-0004(89)90181-3 · Cited by 413
Mayer, B., Schmidt, K., Humbert, P., & Böhme, E. (1989) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(89)91513-1 · Cited by 271
Miilsch, A., & Busse, R. (1990) · Naunyn-Schmiedeberg's Archives of Pharmacology · doi:10.1007/bf00195071 · Cited by 264
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Cited by
Nitric oxide as a secretory product of mammalian cells
Nathan, C. (1992) · The FASEB Journal · doi:10.1096/fasebj.6.12.1381691 · Cited by 4,350
Nitric oxide synthase isozymes. Characterization, purification, molecular cloning, and functions.
Förstermann, U., Closs, E. I., Pollock, J. S., Nakane, M., Schwarz, P., Gath, I., & Kleinert, H. (1994) · Hypertension · doi:10.1161/01.hyp.23.6.1121 · Cited by 1,111
Mammalian nitric oxide synthases
Stuehr, D. J. (1999) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/s0005-2728(99)00016-x · Cited by 996
Microglial-produced nitric oxide and reactive nitrogen oxides mediate neuronal cell death
Boje, K. M., & Arora, P. K. (1992) · Brain Research · doi:10.1016/0006-8993(92)91004-x · Cited by 944
Isoforms of nitric oxide synthase Characterization and purification from different cell types
Förstermann, U., Schmidt, H. H. H. W., Pollock, J. S., Sheng, H., Mitchell, J. A., Warner, T. D., Nakane, M., & Murad, F. (1991) · Biochemical Pharmacology · doi:10.1016/0006-2952(91)90581-o · Cited by 816
Metadata
- Authors
- Busse, R., & Mülsch, A.
- Venue
- FEBS Letters
- Publisher
- Wiley
- Published
- 1990-11-26
- Volume
- 275
- Issue
- 1-2
- Pages
- 87-90
- ISSN
- 0014-5793 (ISSN-L)
- 1873-3468
- OpenAlex
- W2044263892
- Cited by
- 687
- References
- 17
- FWCI
- 30.92
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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