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A novel P‐type ATPase from yeast involved in sodium transport
Open accessAbstract
The gene ENA1 was cloned by its ability to complement the Li+ sensitivity of a low Li+‐efflux strain. The nucleotide sequence of the cloned DNA fragment showed that there are two almost identical genes in tandem, and predicts that they encode P‐ATPases. Disruption of both genes originated a strain defective in Na+ and Li+ effluxes, and sensitive to Na+, to Li+ and to alkaline pH. By transformation with ENA1 the defective effluxes and tolerances were repaired.
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Citations
Cited by
Osmotic Stress Signaling and Osmoadaptation in Yeasts
Hohmann, S. (2002) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.66.2.300-372.2002 · Cited by 1,767
Evolution of Substrate Specificities in the P-Type ATPase Superfamily
Axelsen, K. B., & Palmgren, M. G. (1998) · Journal of Molecular Evolution · doi:10.1007/pl00006286 · Cited by 910
Gaxiola, R. A., Rao, R., Sherman, A., Grisafi, P., Alper, S. L., & Fink, G. R. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.4.1480 · Cited by 600
Stathopoulos, A. M., & Cyert, M. S. (1997) · Genes & Development · doi:10.1101/gad.11.24.3432 · Cited by 442
Cunningham, K. W., & Fink, G. R. (1996) · Molecular and Cellular Biology · doi:10.1128/mcb.16.5.2226 · Cited by 431
Metadata
- Authors
- Haro, R., Garciadeblas, B., & Rodriguez-Navarro, A.
- Venue
- FEBS Letters
- Publisher
- Wiley
- Published
- 1991-10-21
- Volume
- 291
- Issue
- 2
- Pages
- 189-191
- ISSN
- 0014-5793 (ISSN-L)
- 1873-3468
- OpenAlex
- W2068393186
- Cited by
- 357
- References
- 0
- FWCI
- 2.66
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Haro, R., Garciadeblas, B., & Rodriguez-Navarro, A. (1991). A novel P‐type ATPase from yeast involved in sodium transport. FEBS Letters. https://doi.org/10.1016/0014-5793(91)81280-l
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