The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Glycoprotein‐binding site of dystrophin is confined to the cysteine‐rich domain and the first half of the carboxy‐terminal domain
Open accessAbstract
Dystrophin, a protein product of the Duchenne muscular dystrophy gene, is thought to associate with the muscle membrane by way of a glycoprotein complex which was co‐purified with dystrophin. Here, we firstly demonstrate direct biochemical evidence for association of the carboxy‐terminal region of dystrophin with the glycoprotein complex. The binding site is found to lie further inward than previously expected and confined to the cysteine‐rich domain and the first half of the carboxy‐terminal domain. Since this portion corresponds well to the region that, when missing results in severe phenotypes, our findings may provide it molecular basis of the disease.
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Cites
Dystrophin: the protein product of the Duchenne muscular dystrophy locus
Hoffman, E. P., Brown, R. H., & Kunkel, L. M. (1987) · Cell · doi:10.1016/0092-8674(87)90579-4 · Cited by 4,693
Cited by
Function and Genetics of Dystrophin and Dystrophin-Related Proteins in Muscle
Blake, D. J., Weir, A., Newey, S. E., & Davies, K. E. (2002) · Physiological Reviews · doi:10.1152/physrev.00028.2001 · Cited by 1,242
Mendell, J. R., Sahenk, Z., Lehman, K., Nease, C., Lowes, L. P., Miller, N. F., Iammarino, M. A., Alfano, L. N., Nicholl, A., Al-Zaidy, S., et al. (2020) · JAMA Neurology · doi:10.1001/jamaneurol.2020.1484 · Cited by 405
Primary structure of dystrophin-related protein
Tinsley, J. M., Blake, D. J., Roche, A., Fairbrother, U., Riss, J., Byth, B. C., Knight, A. E., Kendrick-Jones, J., Suthers, G. K., Love, D. R., et al. (1992) · Nature · doi:10.1038/360591a0 · Cited by 391
Metadata
- Authors
- Suzuki, A., Yoshida, M., Yamamoto, H., & Ozawa, E.
- Venue
- FEBS Letters
- Publisher
- Wiley
- Published
- 1992-08-17
- Volume
- 308
- Issue
- 2
- Pages
- 154-160
- ISSN
- 0014-5793 (ISSN-L)
- 1873-3468
- OpenAlex
- W2016753696
- Cited by
- 212
- References
- 1
- FWCI
- 9.42
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Suzuki, A., Yoshida, M., Yamamoto, H., & Ozawa, E. (1992). Glycoprotein‐binding site of dystrophin is confined to the cysteine‐rich domain and the first half of the carboxy‐terminal domain. FEBS Letters. https://doi.org/10.1016/0014-5793(92)81265-n
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