Student or educator? Sign up with your school email and get 6 months of Pro free.
CoChat
Sign Up
Cited by 278

The DOI matches its Crossref record.

A P2X purinoceptor cDNA conferring a novel pharmacological profile

Bo, Xuenong, Zhang, Yi, Nassar, Mohammed, Burnstock, Geoffrey, Schoepfer, Ralf·1995·FEBS Letters
DOI 10.1016/0014-5793(95)01203-q
Open this paper in CoChat — free account

Abstract

We have cloned P2X 4, a member of the P2‐purinoceptor family, which has a new pharmacological profile. Rat P2X 4 is distantly related to P2X 1, P2X 2 and P2X 3 and is expressed in brain, spinal cord, lung, thymus, bladder, adrenal, testis and vas deferens. This ligand gated ion channel is activated by ATP and analogs with the potency order of ATP > ATP γ S > 2‐methylthio ATP > ADP ≈ αβ‐methylene ATP. However, none of the currently used P2X purinoceptor antagonists suramin, reactive blue 2 and PPADS blocked ATP evoked currents; in contrast their application resulted in potentiation of the agonist response. Due to lack of any known antagonist for P2X 4 it is unlikely that native P2X 4 has previously been recognized as a P2X purinoceptor.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1016/0014-5793(95)01203-q

Cites

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cited by

See all 278

Metadata

Authors
Bo, X., Zhang, Y., Nassar, M., Burnstock, G., & Schoepfer, R.
Venue
FEBS Letters
Publisher
Wiley
Published
1995-11-13
Volume
375
Issue
1-2
Pages
129-133
ISSN
  • 0014-5793 (ISSN-L)
  • 1873-3468
DOI
10.1016/0014-5793(95)01203-q
OpenAlex
W1968123967
Cited by
278
References
0
FWCI
15.23
Type
journal article
Language
en
Open access
closed

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: A P2X purinoceptor cDNA conferring a novel pharmacological profile. https://app.cochat.ai/papers/10.1016/0014-5793(95)01203-q
The paper
Bo, X., Zhang, Y., Nassar, M., Burnstock, G., & Schoepfer, R. (1995). A P2X purinoceptor cDNA conferring a novel pharmacological profile. FEBS Letters. https://doi.org/10.1016/0014-5793(95)01203-q

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.