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The effect of temperature on the action of thyroid hormone and prolactin in larvae of the salamander Hynobius retardatus
Abstract
To elucidate the environmental factors and endocrine mechanisms which are responsible for inducing neoteny in the salamander Hynobius retardatus, the effect of temperature on the growth and metamorphosis of this amphibian, as well as the actions of thyroid hormone and prolactin at low temperature, were studied. (1) The metamorphosis of larvae cultivated at 10 degrees was significantly delayed compared with that of larvae cultivated at 22 degrees, but the metamorphosis was eventually completed. At 4 degrees, metamorphosis never occurred, even after 2 years. (2) Exogenously administered thyroid hormone accelerated metamorphosis at 10 degrees or 22 degrees, but was ineffective in larvae kept at 4 degrees, whether administered by injection or immersion. (3) If a higher concentration of thyroid hormone was given by a single injection to larvae cultured at 4 degrees, an appreciable acceleration of metamorphosis was observed after transferring the larvae to 22 degrees. (4) Unlike thyroid hormone, prolactin promoted growth at 4 degrees.
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“Our results are contrary to another prediction that neoteny should be more common at the cooler temperatures of higher latitudes, due to inhibition of key hormones for metamorphosis”
From The neoteny goldilocks zone: The evolution of neoteny in Ambystoma (2024) · cites this paper as Moriya, 1983
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Research works printed but not linked: 17
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- Sasaki, 1924, On a Japanese salamander, in the Lake Kuttarush, which propagates like the axolotl, J. Coll. Agr. Hokkaido Imp. Univ, 15, 1
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Cited by
The neoteny goldilocks zone: The evolution of neoteny in Ambystoma
Lyons, T. A., & Arbuckle, K. (2024) · Ecology and Evolution · doi:10.1002/ece3.11240 · Cited by 6
“In contrast, facultatively neotenic species occur at higher elevations than other species, followed by obligately neotenic species and non-neotenic species. to inhibition of key hormones for metamorphosis (Moriya, 1983 ).”
Background
Metadata
- Authors
- Moriya, T.
- Affiliations
- Hokkaido University (JP)
- Corresponding author
- Moriya, Tsuneo
- Venue
- General and Comparative Endocrinology
- Publisher
- Elsevier BV
- Published
- 1983-01
- Volume
- 49
- Issue
- 1
- Pages
- 1-7
- ISSN
- 0016-6480 (ISSN-L)
- OpenAlex
- W2008682242
- Cited by
- 31
- References
- 0
- Citations by year
- 2026: 1 · 2024: 2 · 2022: 1 · 2021: 1 · 2019: 1 · 2018: 1 · 2016: 3 · 2015: 2 · 2013: 1
- FWCI
- 0.32
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- General and Comparative Endocrinology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Ministry of Education, Culture, Sports, Science and Technology
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
- Life Sciences › Agricultural and Biological Sciences › Ecology, Evolution, Behavior and Systematics › Amphibian and Reptile Biology
- Physical Sciences › Environmental Science › Ecology › Physiological and biochemical adaptations
- Keywords
- Hynobius retardatus, neoteny, metamorphosis, thyroid hormones, prolactin, temperature effects, larval growth, amphibian larvae, low temperature
- MeSH terms
- Animals, Larva, Metamorphosis, Biological, Prolactin, Temperature, Thyroid Hormones, Thyroxine, Triiodothyronine, Caudata, Urodela
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- CoChat. (2026). Citation check: The effect of temperature on the action of thyroid hormone and prolactin in larvae of the salamander Hynobius retardatus. https://app.cochat.ai/papers/10.1016/0016-6480(83)90001-1
- The paper
- Moriya, T. (1983). The effect of temperature on the action of thyroid hormone and prolactin in larvae of the salamander Hynobius retardatus. General and Comparative Endocrinology. https://doi.org/10.1016/0016-6480(83)90001-1
