The DOI matches its Crossref record; 52 of the 52 references it cites were found in a registry or an index.
Population correlates of plasma fibrinogen and factor VII, putative cardiovascular risk factors
Abstract
Recent prospective investigations have reported that higher plasma fibrinogen concentrations and higher factor VII coagulant activity are associated with greater risk of cardiovascular disease. To discover what characteristics may influence fibrinogen and factor VII, we analyzed data from the Atherosclerosis Risk in Communities Study obtained from over 12,000 men and women, aged 45-64 years, from four communities in December 1986 to June 1989. Fibrinogen was higher in blacks than whites and in women than men; in general, it increased with age, smoking, body size, diabetes, fasting serum insulin, LDL cholesterol, lipoprotein(a), leukocyte count, and menopause, and it decreased with ethanol intake, physical activity, HDL cholesterol, and female hormone use. Factor VII was higher in women than men and, in women, increased with age; in both sexes, it increased with body size, triglycerides, LDL cholesterol, and HDL cholesterol, and it decreased with ethanol intake. These findings indicate that elevations in fibrinogen and factor VII may be modifiable through appropriate lifestyle changes.
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“Whereas the MS may play a limited role in accelerating atherosclerotic progression, it may significantly increase the risk of vascular events through prothrombotic or inflammatory mechanisms.29 -31”
From Diabetes, the Metabolic Syndrome, and Angiographic Progression of Coronary Arterial Disease in Postmenopausal Women (2006) · cites this paper as [31]
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Rimm, E. B., Williams, P., Fosher, K., Criqui, M., & Stampfer, M. J. (1999) · BMJ · doi:10.1136/bmj.319.7224.1523 · Cited by 1,360
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Self-citationPlasma proteomic signature of age in healthy humans
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Metadata
- Authors
- FOLSOM, A., WU, K., DAVIS, C., CONLAN, M., SORLIE, P., & SZKLO, M.
- Affiliations
- University of Minnesota (US)
- National Heart, Lung, and Blood Institute (US)
- Johns Hopkins University (US)
- Corresponding author
- FOLSOM, A
- Venue
- Atherosclerosis
- Publisher
- Elsevier BV
- Published
- 1991-12
- Volume
- 91
- Issue
- 3
- Pages
- 191-205
- ISSN
- 0021-9150 (ISSN-L)
- OpenAlex
- W2001322531
- Cited by
- 321
- References
- 52
- Citations by year
- 2024: 1 · 2023: 3 · 2022: 2 · 2021: 1 · 2019: 1 · 2018: 5 · 2017: 1 · 2016: 2 · 2015: 3 · 2014: 2 · 2013: 2 · 2012: 6
- FWCI
- 21.70
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Atherosclerosis (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Northwestern University
- National Institutes of Health (n01hc55016-37-0-0, n01hc55018-38-0-1, n01hc55015-48-0-1)
- National Heart, Lung, and Blood Institute (N01-HC-55018, N01-HC55016, N01‐HC‐55015)
- Topics
- Health Sciences › Medicine › Hematology › Blood properties and coagulation
- Health Sciences › Medicine › Hematology › Blood Coagulation and Thrombosis Mechanisms
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipoproteins and Cardiovascular Health
- Keywords
- fibrinogen, factor VII coagulant activity, cardiovascular risk factors, cardiovascular disease, Atherosclerosis Risk in Communities Study, sex differences, racial differences, modifiable lifestyle factors, smoking, alcohol consumption, physical activity, diabetes mellitus, insulin, lipoprotein(a), LDL cholesterol, HDL cholesterol, triglycerides, menopause, white blood cell count, aging
- MeSH terms
- Body Constitution, Cardiovascular Diseases, Coronary Disease, Factor VII, Female, Fibrinogen, Humans, Life Style, Lipids, Male, Middle Aged, Prospective Studies, Risk Factors, Sex Factors, Smoking, Racial Groups
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