The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.
Histometric study of myelinated fibers in the human trigeminal nerve
Abstract
The trigeminal ganglion, roots and the initial portion of the ophthalmic, maxillary and mandibular nerves were dissected in 3 cadavers, to study the number, area and composition of the fascicles, and the density and diameter spectra of myelinated fibers. The total number of fibers (x 1000) was 26 in the ophthalmic, 50 in the maxillary, and 78 in the mandibular division, 7.7 in the motor root and 170 in the sensory root. In all nerves, the histograms of fiber diameter had a bimodal distribution. Cutaneous and muscle nerve fascicles clearly differed in the fiber density and diameter. The ophthalmic and maxillary nerves (cutaneous) had similar fascicles, and their maximum fiber diameter averaged 14.5 microns. Most fascicles of the mandibular nerve (probably cutaneous fascicles) closely resembled those of the ophthalmic and maxillary nerves, but in some fascicles (probably muscle nerves) the fibers were larger, with a maximum diameter of 19.3 microns. The findings in the three peripheral divisions agree with electrophysiological data about sensory and motor conduction in human trigeminal nerves. The observation that the ophthalmic and maxillary nerves have similar fiber spectra indicates that a special fiber composition does not account for the sparing of the ophthalmic division in trigeminal neuralgia. The absence of very large (A alpha) fibers in the sensory root does not support the view that impulses from muscle spindles are conducted along this root.
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“In this root, the total number of fibers is estimated at 170,000, and 62,000 of these are myelinated and fall within the diameter range of Ab fibers (Pennisi et al. 1991).”
From Tactile innervation densities across the whole body (2020) · cites this paper as Pennisi et al. 1991
Citations
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QUAN ĐIỂM Y HỌC HIỆN ĐẠI VÀ Y HỌC CỔ TRUYỀN TRONG ĐIỀU TRỊ ĐAU THẦN KINH SAU ZONA
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Metadata
- Authors
- Pennisi, E., Cruccu, G., Manfredi, M., & Palladini, G.
- Affiliations
- Sapienza University of Rome (IT)
- Venue
- Journal of the Neurological Sciences
- Publisher
- Elsevier BV
- Published
- 1991-09
- Volume
- 105
- Issue
- 1
- Pages
- 22-28
- ISSN
- 0022-510X (ISSN-L)
- OpenAlex
- W2041288000
- Cited by
- 43
- References
- 24
- Citations by year
- 2025: 1 · 2024: 4 · 2023: 3 · 2022: 1 · 2021: 2 · 2020: 2 · 2019: 1 · 2018: 2 · 2017: 1 · 2016: 1 · 2014: 1 · 2012: 3
- FWCI
- 0.37
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of the Neurological Sciences (publishedVersion)
- PubMed (publishedVersion)
- IRIS Research product catalog (Sapienza University of Rome) (submittedVersion)
- Topics
- Health Sciences › Medicine › Clinical Neurology › Trigeminal Neuralgia and Treatments
- Health Sciences › Medicine › Anatomy › Classical Anatomy and Histology
- Health Sciences › Medicine › Clinical Neurology › Peripheral Nerve Disorders
- Keywords
- trigeminal nerve, myelinated axons, fiber diameter distribution, fiber density, trigeminal ganglion, ophthalmic nerve, maxillary nerve, mandibular nerve, trigeminal neuralgia, muscle spindle afferents
- MeSH terms
- Humans, Mandibular Nerve, Maxillary Nerve, Middle Aged, Nerve Fibers, Myelinated, Trigeminal Nerve
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