Correlation between altered acetate utilization and hyperphagia in rats with ventromedial hypothalamic lesions
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Spontaneous physical activity is reduced during development of ventromedial hypothalamic obesity and increased fat deposition occurs even with restriction of food intake to that of controls.
“Importantly, spontaneous physical activity is reduced during development of ventromedial hypothalamic obesity and increased fat deposition occurs even with restriction of food intake to that of controls.”
From The carbohydrate-insulin model: A physiological perspective on the obesity pandemic (2021) · cites this paper as [118]
Immediately after injury to the ventromedial hypothalamus, hyperinsulinemia develops without systemic insulin resistance, and sympathetic nervous system tone is decreased.
“Immediately after injury to the ventromedial hypothalamus, hyperinsulinemia develops without systemic insulin resistance, and sympathetic nervous system tone is decreased.”
From The carbohydrate-insulin model: A physiological perspective on the obesity pandemic (2021) · cites this paper as [118]
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References 16 · Cited by 15
- Authors
- Løvø, A., & Hustvedt, B.-E.
- Affiliations
- University of Oslo (NO)
- Venue
- Metabolism
- Publisher
- Elsevier BV
- Published
- 1973-12
- Volume
- 22
- Issue
- 12
- Pages
- 1459-1465
- ISSN
- 0026-0495 (ISSN-L)
- OpenAlex
- W2015140423
- Cited by
- 15
- References
- 16
- Citations by year
- 2024: 1 · 2021: 1
- FWCI
- 1.34
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Metabolism (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
- Health Sciences › Medicine › Reproductive Medicine › Hypothalamic control of reproductive hormones
- Health Sciences › Medicine › Epidemiology › Adipokines, Inflammation, and Metabolic Diseases
- Keywords
- ventromedial hypothalamus, hypothalamic lesions, hyperphagia, acetate utilization, acetate-1-14C, body fat accumulation, lipid incorporation, weight gain, food intake regulation
- MeSH terms
- Acetates, Animals, Feeding and Eating Disorders, Carbon Dioxide, Carbon Radioisotopes, Female, Humans, Hypothalamus, Lipids, Obesity, Stereotaxic Techniques, Time Factors, Rats
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