The DOI matches its Crossref record.
Failure of high dose mebendazole as a microfilaricide in patients with loiasis
Abstract
The effectiveness of mebendazole as a microfilaricide in patients with loiasis was studied. The drug regimen was 1 g twice daily for 21 days in adults. During and after treatment, the microfilarial density was unchanged. Therefore, mebendazole has no direct effect on the microfilarial density of Loa loa.
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In the citing paper
“although the same mebendazole regimen (2 g daily for 21 days) revealed no significant decrease in microfilaremia [233]”
From Albendazole and Mebendazole as Anti-Parasitic and Anti-Cancer Agents: an Update (2021) · cites this paper as [233]
Citations
Cites
No references could be resolved yet.
Research works printed but not linked: 4
- Brugmans, 1971, Mebendazole in enterobiasis. Radiochemical and pilot clinical study in 1278 subjects, Journal of the American Medical Association, 217, 313, 10.1001/jama.217.3.313 · DOI
- Richard-Lenoble, 1985, Filariose au Gabon: traitement par le mebendazole des filarioses à M. perstans et Loa loa, Bulletin de la Société Pathologie Exotique, 78, 485
- Van Hoegaerden, 1985, Mebendazole treatment of loiasis, Lancet, ii, 1278, 10.1016/S0140-6736(85)92350-5 · DOI
- Wahlgren, 1983, Treatment of Dipetalonema perstans infections with mebendazole, Transactions of the Royal Society of Tropical Medicine and Hygiene, 77, 359, 10.1016/0035-9203(83)90179-7 · DOI · Paper page
Cited by
Sorted by citations
Albendazole and Mebendazole as Anti-Parasitic and Anti-Cancer Agents: an Update
Chai, J.-Y., Jung, B.-K., & Hong, S.-J. (2021) · The Korean Journal of Parasitology · doi:10.3347/kjp.2021.59.3.189 · Cited by 286
Metadata
- Authors
- Burchard, G. D., & Kern, P.
- Affiliations
- Albert Schweitzer Hospital (GA)
- Venue
- Transactions of the Royal Society of Tropical Medicine and Hygiene
- Publisher
- Oxford University Press (OUP)
- Published
- 1987-01
- Volume
- 81
- Issue
- 3
- Pages
- 420
- ISSN
- 0035-9203 (ISSN-L)
- OpenAlex
- W2009374351
- Cited by
- 16
- References
- 0
- Citations by year
- 2025: 2 · 2021: 1 · 2016: 1 · 2014: 1 · 2013: 1
- FWCI
- 1.37
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Transactions of the Royal Society of Tropical Medicine and Hygiene (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Infectious Diseases › Parasitic Diseases Research and Treatment
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Research on Leishmaniasis Studies
- Life Sciences › Immunology and Microbiology › Parasitology › Parasites and Host Interactions
- Keywords
- mebendazole, loiasis, Loa loa, microfilarial density, anthelmintic treatment, drug efficacy
- MeSH terms
- Clinical Trials as Topic, Filariasis, Humans, Loiasis, Mebendazole
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