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Cutaneous basophil hypersensitivity

Dvorak, Harold F.·1976·Journal of Allergy and Clinical Immunology
DOI 10.1016/0091-6749(76)90159-7
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Abstract

Cutaneous basophil hypersensitivity (CBH) is a distinct form of lymphocyte-mediated hypersensitivity in guinea pigs, separate both from classic delayed hypersensitivity (DH) and from the well-known antibody-mediated reactions. CBH, not DH, is the usual cellular immune response of this species to a wide variety of immunogens (e.g., allografts, certain parasites, and viruses) when these are presented in native form without supplementation with mycobacteria-containing adjuvants, thus attesting to the importance of this response in the guinea pig's overall immune defense mechanism. Basophil-containing, cell-mediated, delayed-onset reactions occur in other species, including man, as well.

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Research works printed but not linked: 40

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Metadata

Authors
Dvorak, H. F.
Venue
Journal of Allergy and Clinical Immunology
Publisher
Elsevier BV
Published
1976-07
Volume
58
Issue
1
Pages
229-240
ISSN
0091-6749
DOI
10.1016/0091-6749(76)90159-7
Cited by
65
References
0
Language
en
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