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Cited by 216RNA and protein synthesis mechanismsPI3K/AKT/mTOR signaling in cancerRNA Research and Splicing

Evaluation of the “scanning model” for initiation of protein synthesis in eucaryotes

Kozak, Marilyn·1980·Cell
DOI 10.1016/0092-8674(80)90148-8
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  • Efficient translation initiation in mammalian species depends mainly on the Kozak consensus.

    “Efficient translation initiation in mammalian species depends mainly on two factors [40,41]: (1) the Kozak consensus [42,43,44], and (2) the secondary structure that may embed the Kozak consensus to obscure these essential translation initiation signals [9,41,45].”

    From Detailed Dissection and Critical Evaluation of the Pfizer/BioNTech and Moderna mRNA Vaccines (2021) · cites this paper as [42]

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Authors
Kozak, M.
Affiliations
University of Pittsburgh (US)
Corresponding author
Kozak, Marilyn
Venue
Cell
Publisher
Elsevier BV
Published
1980-11
Volume
22
Issue
1
Pages
7-8
ISSN
0092-8674 (ISSN-L)
DOI
10.1016/0092-8674(80)90148-8
OpenAlex
W2043986644
Cited by
216
References
0
Citations by year
2026: 3 · 2025: 1 · 2024: 3 · 2023: 2 · 2022: 3 · 2021: 6 · 2020: 1 · 2018: 8 · 2017: 6 · 2016: 4 · 2015: 3 · 2013: 5 · 2012: 1
FWCI
7.61
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Cell (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA and protein synthesis mechanisms
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › PI3K/AKT/mTOR signaling in cancer
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA Research and Splicing
Keywords
scanning model, translation initiation, protein synthesis initiation, eukaryotic translation, ribosome scanning
MeSH terms
Base Sequence, Cells, Codon, Eukaryotic Cells, Models, Biological, Movement, Peptide Chain Initiation, Translational, Ribosomes, RNA, Messenger, Templates, Genetic

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