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DNA methylation affects the formation of active chromatin
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Citations
Cited by
Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
Jones, P. L., Veenstra, G. J. C., Wade, P. A., Vermaak, D., Kass, S. U., Landsberger, N., Strouboulis, J., & Wolffe, A. P. (1998) · Nature Genetics · doi:10.1038/561 · Cited by 2,730
The history of cancer epigenetics
Feinberg, A. P., & Tycko, B. (2004) · Nature Reviews Cancer · doi:10.1038/nrc1279 · Cited by 2,344
CpG island hypermethylation and tumor suppressor genes: a booming present, a brighter future
Esteller, M. (2002) · Oncogene · doi:10.1038/sj.onc.1205600 · Cited by 1,233
Targeting epigenetic regulators for cancer therapy: mechanisms and advances in clinical trials
Cheng, Y., He, C., Wang, M., Ma, X., Mo, F., Yang, S., Han, J., & Wei, X. (2019) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-019-0095-0 · Cited by 1,097
“The precise mechanism by which DNA methylation affects chromatin structure unclear, but it is known that methyl-DNA is closely associated with a closed chromatin structure, which is relatively inactive.(19) Hypermethylation of promoters and hypomethylation of global DNA are quite common in cancer.”
BackgroundDynamic changes in the human methylome during differentiation
Laurent, L., Wong, E., Li, G., Huynh, T., Tsirigos, A., Ong, C. T., Low, H. M., Kin Sung, K. W., Rigoutsos, I., Loring, J., et al. (2010) · Genome Research · doi:10.1101/gr.101907.109 · Cited by 1,041
Metadata
- Authors
- Keshet, I., Lieman-Hurwitz, J., & Cedar, H.
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 1986-02
- Volume
- 44
- Issue
- 4
- Pages
- 535-543
- ISSN
- 0092-8674 (ISSN-L)
- OpenAlex
- W2020824064
- Cited by
- 588
- References
- 0
- FWCI
- 12.85
- Type
- journal article
- Language
- en
- Open access
- closed
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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- CoChat. (2026). Citation check: DNA methylation affects the formation of active chromatin. https://app.cochat.ai/papers/10.1016/0092-8674(86)90263-1
- The paper
- Keshet, I., Lieman-Hurwitz, J., & Cedar, H. (1986). DNA methylation affects the formation of active chromatin. Cell. https://doi.org/10.1016/0092-8674(86)90263-1
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.