The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

Lee, Rosalind C., Feinbaum, Rhonda L., Ambros, Victor·1993·Cell

DOI 10.1016/0092-8674(93)90529-y

Cited by (1,060)

Items 801–900 of 1,060

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J Contreras, Dinesh S. Rao · 2011 · Leukemia
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Peter J. Kahrilas, Guy E. Boeckxstaens · 2013 · Gastroenterology
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Yehu Moran, Maayan Agron, Daniela Praher, Ulrich Technau · 2017 · Nature Ecology & Evolution
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Angela Bik‐Yu Hui, Wei Shi, Paul Christopher Boutros, Naomi A Miller, Melania Pintilie, T.W. Fyles, David R. McCready, Derek Wong, Kate Gerster, Igor Jurišica et al. · 2009 · Laboratory Investigation
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Eric G. Moss · 2007 · Current Biology
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Christine Hunter, Hui Sun, R. Scott Poethig · 2003 · Current Biology
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Huiyuan Wang, Yifan Jiang, Huige Peng, Yingzhi Chen, Peizhi Zhu, Yongzhuo Huang · 2014 · Advanced Drug Delivery Reviews
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John S. Mattick · 2007 · Journal of Experimental Biology
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Zhong‐Ping Feng, Congcong Zhang, Rui Wu, Wanglai Hu · 2011 · Journal of Molecular Cell Biology
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Xing Chen, Chenggang Clarence Yan, Xu Zhang, Zhu‐Hong You, Yu‐An Huang, Guiying Yan · 2016 · Oncotarget
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Ilias Alevizos, Gabor G. Illei · 2010 · Nature Reviews Rheumatology
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Daniel Boden · 2004 · Nucleic Acids Research
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Liqiang Qi, Joost Bart, Lu Ping Tan, Inge Platteel, Tineke van der Sluis, Sippie Huitema, Geert Harms, Li Fu, Harry Hollema, Anke van den Berg · 2009 · BMC Cancer
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Junfen Xu, Y Li, F Wang, X Wang, B Cheng, Fenglei Ye, Xing Xie, Caiyun Zhou, Weiguo Lü · 2012 · Oncogene
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Ricardo A. Chávez Montes, Flor de Fátima Rosas‐Cárdenas, Emanuele De Paoli, Monica Accerbi, Linda A. Rymarquis, Gayathri Mahalingam, Nayelli Marsch‐Martínez, Blake C. Meyers, Pamela J. Green, Stefan de Folter · 2014 · Nature Communications
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