The Cockayne syndrome group A gene encodes a WD repeat protein that interacts with CSB protein and a subunit of RNA polymerase II TFIIH

Henning, Karla A.; Li, Lei; Iyer, Narayan; McDaniel, Lisa D.; Reagan, Michael S.; Legerski, Randy; Schultz, Roger A.; Stefanini, Miria; Lehmann, Alan R.; Mayne, Lynne V.; Friedberg, Errol C.

doi:10.1016/0092-8674(95)90028-4

The Cockayne syndrome group A gene encodes a WD repeat protein that interacts with CSB protein and a subunit of RNA polymerase II TFIIH

The hereditary disease Cockayne syndrome (CS) is characterized by a complex clinical phenotype. CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes. The cloned CSB gene encodes a member of a protein family that includes the …