The DOI matches its Crossref record; 53 of the 53 references it cites were found in a registry or an index.
Different forms of TFIIH for transcription and DNA repair: Holo-TFIIH and a nucleotide excision repairosome
Open accessAbstract
Yeast TFIIH that is active in transcription can be dissociated into three components: a 5-subunit core, the SSL2 gene product, and a complex of 47 kDa, 45 kDa, and 33 kDa polypeptides that possesses protein kinase activity directed towards the C-terminal repeat domain of RNA polymerase II. These three components can reconstitute fully functional TFIIH, and all three are required for transcription in vitro. By contrast, TFIIH that is highly active in nucleotide excision repair (NER) lacks the kinase complex and instead contains the products of all other genes known to be required for NER in yeast: RAD1, RAD2, RAD4, RAD10, and RAD14. This repairosome is not active in reconstituted transcription in vitro and is significantly more active than any of the constituent polypeptides in correcting defective repair in extracts from strains mutated in NER genes.
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Self-citationProliferating cell nuclear antigen is required for DNA excision repair
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DNA Repair Helicase: a Component of BTF2 (TFIIH) Basic Transcription Factor
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Dual role of TFIIH in DNA excision repair and in transcription by RNA polymerase II
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The MO15 cell cycle kinase is associated with the TFIIH transcription-DNA repair factor
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Relationship of CDK-activating kinase and RNA polymerase II CTD kinase TFIIH/TFIIK
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Cited by
Molecular mechanism of nucleotide excision repair
de Laat, W. L., Jaspers, N. G. J., & Hoeijmakers, J. H. J. (1999) · Genes & Development · doi:10.1101/gad.13.7.768 · Cited by 1,122
How nucleotide excision repair protects against cancer
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Self-citationNucleotide excision repair and human syndromes
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Molecular Mechanisms of Mammalian Global Genome Nucleotide Excision Repair
Gillet, L. C. J., & Schärer, O. D. (2006) · Chemical Reviews · doi:10.1021/cr040483f · Cited by 642
Mediator and the mechanism of transcriptional activation
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Metadata
- Authors
- Svejstrup, J. Q., Wang, Z., Feave, W. J., Wu, X., Bushnell, D. A., Donahue, T. F., Friedberg, E. C., & Kornberg, R. D.
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 1995-01
- Volume
- 80
- Issue
- 1
- Pages
- 21-28
- ISSN
- 0092-8674 (ISSN-L)
- OpenAlex
- W2039068784
- Cited by
- 278
- References
- 53
- FWCI
- 14.09
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Svejstrup, J. Q., Wang, Z., Feave, W. J., Wu, X., Bushnell, D. A., Donahue, T. F., Friedberg, E. C., & Kornberg, R. D. (1995). Different forms of TFIIH for transcription and DNA repair: Holo-TFIIH and a nucleotide excision repairosome. Cell. https://doi.org/10.1016/0092-8674(95)90447-6
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