Glutathione deficiency and human immunodeficiency virus infection

Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF‐kappa B transcription factor and HIV‐1.

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An inducible transcription factor activates expression of human immunodeficiency virus in T cells

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Glutathione metabolism and its selective modification.

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Efficacy of Oral N-Acetylcysteine in the Treatment of Acetaminophen Overdose

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Intracellular thiols regulate activation of nuclear factor kappa B and transcription of human immunodeficiency virus.

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TNF concentration in fatal cerebral, non-fatal cerebral, and uncomplicated Plasmodium falciparum malaria

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Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions.

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SYSTEMIC GLUTATHIONE DEFICIENCY IN SYMPTOM-FREE HIV-SEROPOSITIVE INDIVIDUALS

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Interleukin 6 induces human immunodeficiency virus expression in infected monocytic cells alone and in synergy with tumor necrosis factor alpha by transcriptional and post-transcriptional mechanisms.

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Glutathione regulates activation-dependent DNA synthesis in highly purified normal human T lymphocytes stimulated via the CD2 and CD3 antigens.

Suthanthiran, M., Anderson, M. E., Sharma, V. K., & Meister, A. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.9.3343 · Cited by 382

Cytokine-stimulated human immunodeficiency virus replication is inhibited by N-acetyl-L-cysteine.

Roederer, M., Staal, F. J. T., Raju, P. A., Ela, S. W., Herzenberg, L. A., & Herzenberg, L. A. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.12.4884 · Cited by 376

Low Concentrations of Acid-Soluble Thiol (Cysteine) in the Blood Plasma of HIV-1-Infected Patients

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Suppression of human immunodeficiency virus expression in chronically infected monocytic cells by glutathione, glutathione ester, and N-acetylcysteine.

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Selective Depletion in HIV Infection of T Cells that Bear Specific T Cell Receptor V β Sequences

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Inhibition of HIV-1 replication and NF-x B activity by cysteine and cysteine derivatives

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Effect of N-acetylcysteine on plasma cysteine and glutathione following paracetamol administration

Burgunder, J., Varriale, A., & Lauterburg, B. H. (1989) · European Journal of Clinical Pharmacology · doi:10.1007/bf00609183 · Cited by 232

N -Acetylcysteine: A New Approach to Anti-HIV Therapy

Roederer, M., Ela, S. W., Staal, F. J. T., Herzenberg, L. A., & Herzenberg, L. A. (1992) · AIDS Research and Human Retroviruses · doi:10.1089/aid.1992.8.209 · Cited by 163

Intracellular Glutathione Levels in T Cell Subsets Decrease in HIV-Infected Individuals

Staal, F. J. T., Roederer, M., Israelski, D. M., Bubp, J. L., Mole, L. A., McShane, D. J., Deresinski, S. C., Ross, W. A., Sussman, H. H., Raju, P. A., et al. (1992) · AIDS Research and Human Retroviruses · doi:10.1089/aid.1992.8.305 · Cited by 156

The role of glutathione in lymphocyte activation. I. Comparison of inhibitory effects of buthionine sulfoximine and 2-cyclohexene-1-one by nuclear size transformation.

Hamilos, D. L., & Wedner, H. J. (1985) · The Journal of Immunology · doi:10.4049/jimmunol.135.4.2740 · Cited by 153

CD4 and CD8 T cells with high intracellular glutathione levels are selectively lost as the HIV infection progresses

Roederer, M., Staal, F. J. T., Osada, H., Herzenberg, L. A., & Herzenberg, L. A. (1991) · International Immunology · doi:10.1093/intimm/3.9.933 · Cited by 144

Anti-HIV and Anti-Anti-MHC Antibodies in Alloimmune and Autoimmune Mice

Kion, T. A., & Hoffmann, G. W. (1991) · Science · doi:10.1126/science.1909456 · Cited by 135

Oxidative stress and abnormal cholesterol metabolism in patients with adult respiratory distress syndrome.

Cross, C. E., Forte, T. M., Stocker, R., Louie, S., Yamamoto, Y., Ames, B. N., & Frei, B. B. (1990) · PubMed · Cited by 122

Pentoxifylline (Trental) decreases the replication of the human immunodeficiency virus type 1 in human peripheral blood mononuclear cells and in cultured T cells [see comments]

Fazely, F., Dezube, B. J., Allen-Ryan, J., Pardee, A., & Ruprecht, R. (1991) · Blood · doi:10.1182/blood.v77.8.1653.1653 · Cited by 109

Reactive oxygen species, antioxidants, and acquired immunodeficiency syndrome. Sense or speculation?

Halliwell, B. B. (1991) · Archives of Internal Medicine · doi:10.1001/archinte.151.1.29 · Cited by 96

Gluthatione Augments the Activation of Cytotoxic T Lymphocytes in vivo

Dröge, W., Pottmeyer-Gerber, C., Schmidt, H., & Nick, S. (1986) · Immunobiology · doi:10.1016/s0171-2985(86)80061-4 · Cited by 95

L-2-oxothiazolidine-4-carboxylic acid, a cysteine prodrug: pharmacokinetics and effects on thiols in plasma and lymphocytes in human.

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N-Acetylcysteine Inhibits Latent HIV Expression in Chronically Infected Cells

Roederer, M., Raju, P. A., Staal, F. J. T., Herzenberg, L. A., & Herzenberg, L. A. (1991) · AIDS Research and Human Retroviruses · doi:10.1089/aid.1991.7.563 · Cited by 73

Comparative study of the anti-HIV activities of ascorbate and thiol-containing reducing agents in chronically HIV-infected cells

Harakeh, S., & Jariwalla, R. J. (1991) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/54.6.1231s · Cited by 67

Metabolic disorder as early consequence of simian immunodeficiency virus infection in rhesus macaques

Eck, H., Dröge, W., Stahl‐Hennig, C., & Hunsmann, G. (1991) · The Lancet · doi:10.1016/0140-6736(91)90482-5 · Cited by 64

Reactive Oxygen Species, Antioxidants, and Acquired Immunodeficiency Syndrome

Halliwell, B. B. (1991) · Archives of Internal Medicine · doi:10.1001/archinte.1991.00400010053005 · Cited by 59

Membrane Oxidative Metabolism of Human Eosinophilic Cell Line EoL-1 in Response to Phorbol Diester and Formyl Peptide: Synergistic Augmentation by Interferon-γ Tumor Necrosis Factor

Yoshie, O., Majima, T., & Saito, H. (1989) · Journal of Leukocyte Biology · doi:10.1002/jlb.45.1.10 · Cited by 32

Prolonged antiviral activity of D-penicillamine in human immunodeficiency virus-infected homosexual men

Scheib, R. G., Parenti, D. M., Simon, G. L., Courtless, J., Schulof, R. S., Sarin, P. S., & Chandra, P. (1987) · The American Journal of Medicine · doi:10.1016/0002-9343(87)90794-7 · Cited by 14

REDOX REGULATION OF CELLULAR ACTIVATION

Nakamura, H., Nakamura, K., & Yodoi, J. (1997) · Annual Review of Immunology · doi:10.1146/annurev.immunol.15.1.351 · Cited by 1,106

Glutathione deficiency is associated with impaired survival in HIV disease

Herzenberg, L. A., Rosa, S. C. D., Dubs, J. G., Roederer, M., Anderson, M. T., Ela, S. W., Deresinski, S. C., & Herzenberg, L. A. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.5.1967 · Cited by 672

Oxidative stress during viral infection: A review

Schwarz, K. B. (1996) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(96)00131-1 · Cited by 652

Thiol-addition reactions and their applications in thiol recognition

Yin, C., Huo, F., Zhang, J., Martínez‐Máñez, R., Yang, Y.-T., Lv, H., & Li, S. (2013) · Chemical Society Reviews · doi:10.1039/c3cs60055f · Cited by 553

Zinc Metabolism in the Brain: Relevance to Human Neurodegenerative Disorders

Cuajungco, M. P., & Lees, G. J. (1997) · Neurobiology of Disease · doi:10.1006/nbdi.1997.0163 · Cited by 544

Glutathione deficiency and HIV infection

Robinson, M. K., Hong, R., & Wilmore, D. W. (1992) · The Lancet · doi:10.1016/0140-6736(92)91864-5 · Cited by 12

Glutathione deficiency and HIV

Buhl, R., Jaffe, H. A., Holroyd, K. J., Wells, F. B., Mastrangeli, A., Saltini, C., Cantin, A. M., & Crystal, R. G. (1990) · The Lancet · doi:10.1016/0140-6736(90)90783-2 · Cited by 19

Glutathione deficiency in human HIV infection

Giorgi, G., Micheli, L., Fiaschi, A. I., Pra, P. D., & Bozzo, M. (1990) · Pharmacological Research · doi:10.1016/s1043-6618(09)80264-8 · Cited by 6

Glutathione Deficiency in Hiv-Infected Patients: A True or Technical Deficiency?

Pirmohamed, M., Williams, D., Khoo, S., Barry, M. G., Breckenridge, A., & Park, B. K. (1996) · Clinical Science · doi:10.1042/cs091009pb

The role of a cysteine and glutathione deficiency in the immunopathology of HIV infection.

Dröge, W., Eck, H., Mihm, S., Roth, S., Kinscherf, R., & Fischbach, T. J. (1994) · PubMed · Cited by 7