Cited by 238Bladder and Urothelial Cancer TreatmentsUrinary and Genital Oncology StudiesCancer Genomics and Diagnostics

The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.

Genetic alterations in bladder cancer

Dalbagni, G., Presti, J., Fair, W.R., Reuter, V., Cordon-Cardo, C.·1993·The Lancet

Open this paper in CoChat — free account

Abstract

To see whether genetic alterations follow a sequence of events leading to bladder cancer progression, 60 paired bladder tumours and normal tissues were analysed with polymorphic DNA markers, correlating loss of heterozygosity (LOH) at candidate tumour suppressor gene sites with pathological indices of poor clinical outcome. Distinct genotypic patterns were associated with early and late stages of bladder cancer. 9q deletions were observed in all superficial papillary tumours (Ta) and almost all tumours invading the lamina propria (T1), suggesting that this event associates with the development of superficial bladder tumours. However, 3p, 5q, and 17p deletions were absent in the Ta tumours but were identified in invasive bladder cancers. Two genetic pathways characterise the evolution of superficial bladder tumours. 9qLOH was detected in most Ta tumours, but in only 43% of muscle invasive neoplasms. Our hypothesis is that certain chromosomal abnormalities have a defined role in bladder tumour development, whereas others correlate with pathological indices of poor clinical outcome.

Integrity signals

Registry

Crossref · 10.1016/0140-6736(93)91595-d

Cites

9 of 9 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Identification of the von Hippel-Lindau Disease Tumor Suppressor Gene
Latif, F., Tory, K., Gnarra, J. R., Yao, M., Duh, F.-M. C., Orcutt, M. L., Stackhouse, T. M., Kuzmin, I., Modi, W. S., Geil, L., et al. (1993) · Science · doi:10.1126/science.8493574 · Cited by 2,971
Identification of FAP Locus Genes from Chromosome 5q21
Kinzler, K. W., Nilbert, M. C., Su, L.-K., Vogelstein, B., Bryan, T. M., Levy, D. B., Smith, K. J., Preisinger, A. C., Hedge, P., McKechnie, D., et al. (1991) · Science · doi:10.1126/science.1651562 · Cited by 2,331
Allelotype of Colorectal Carcinomas
Vogelstein, B., Fearon, E. R., Kern, S. E., Hamilton, S. R., Preisinger, A. C., Nakamura, Y., & White, R. L. (1989) · Science · doi:10.1126/science.2565047 · Cited by 1,302
Location of gene for Gorlin syndrome
Farndon, P. A., Mastro, R. G. D., Kilpatrick, M. W., & Evans, D. G. (1992) · The Lancet · doi:10.1016/0140-6736(92)90868-4 · Cited by 397
Altered Expression of the Retinoblastoma Gene Product: Prognostic Indicator in Bladder Cancer
Cordon‐Cardo, C., Wartinger, D. D., Petrylak, D. P., Dalbagni, G. M., Fair, W. R., FUKS, Z. Y., & Reuter, V. E. (1992) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/84.16.1251 · Cited by 334
Self-citation
Altered Expression of Retinoblastoma Protein and Known Prognostic Variables in Locally Advanced Bladder Cancer
Logothetis, C. J., Xu, H., Ro, J. Y., Hu, S., Şahin, A., Ordóǹez, N. G., & Benedict, W. F. (1992) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/84.16.1256 · Cited by 244
Molecular genetic alterations in superficial and locally advanced human bladder cancer.
Presti, J. C., Reuter, V. E., Galan, T. I., Fair, W. R., & Cordón-Cardó, C. (1991) · PubMed · Cited by 230
Self-citation
Allelotype of human breast carcinoma: a second major site for loss of heterozygosity is on chromosome 6q.
Devilee, P., van Vliet, M., van Sloun, P., Kuipers‐Dijkshoorn, N. J., Hermans, J., Pearson, P. L., & Cj, C. (1991) · PubMed · Cited by 195
Cytogenetic Studies of Carcinoma in Situ of the Bladder: Prognostic Implications
Tyrkus, M., Powell, I. J., & Fakr, W. (1992) · The Journal of Urology · doi:10.1016/s0022-5347(17)36504-7 · Cited by 38

Show all 9 references

Sorted by citations

Urothelial tumorigenesis: a tale of divergent pathways
Wu, X. (2005) · Nature reviews. Cancer · doi:10.1038/nrc1697 · Cited by 696
Two molecular pathways to transitional cell carcinoma of the bladder.
Spruck, C., Ohneseit, P. F., Gonzalez‐Zulueta, M., Esrig, D., Miyao, N., Tsai, Y., Lerner, S. P., Schmütte, C., Yang, A. S., & Cote, R. (1994) · PubMed · Cited by 601
Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control
Hernando, E., Nahlé, Z., Juan, G., Diaz-Rodriguez, E., Alaminos, M., Hemann, M., Michel, L., Mittal, V., Gerald, W., Benezra, R., et al. (2004) · Nature · doi:10.1038/nature02820 · Cited by 562
Self-citation
Defining Molecular Profiles of Poor Outcome in Patients With Invasive Bladder Cancer Using Oligonucleotide Microarrays
Sänchez‐Carbayo, M., Socci, N. D., Lozano, J., Saint, F., & Cordon‐Cardo, C. (2006) · Journal of Clinical Oncology · doi:10.1200/jco.2005.03.2375 · Cited by 549
Self-citation
Mutations of cell cycle regulators. Biological and clinical implications for human neoplasia.
Cordon‐Cardo, C. (1995) · PubMed Central · Cited by 527
Self-citation
Bladder tumor markers beyond cytology: International Consensus Panel on bladder tumor markers
Lokeshwar, V. B., Habuchi, T., Grossman, H. B., Murphy, W. M., HAUTMANN, S. H., Hemstreet, G. P., Bono, A. V., Getzenberg, R. H., Goebell, P. J., Schmitz‐Dräger, B. J., et al. (2005) · Urology · doi:10.1016/j.urology.2005.08.064 · Cited by 430
Bladder Cancer Outcome and Subtype Classification by Gene Expression
Blaveri, E., Simko, J. P., Korkola, J. E., Brewer, J. L., Baehner, F. L., Mehta, K. R., DeVries, S., Koppie, T. M., Pejavar, S., Carroll, P. R., et al. (2005) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-04-2409 · Cited by 339
Deletions of the Short Arm of Chromosome 3 in Solid Tumors and the Search for Suppressor Genes
Kok, K., Naylor, S. L., & Buys, C. H. C. M. (1997) · Advances in cancer research · doi:10.1016/s0065-230x(08)60096-2 · Cited by 334
Genetic alterations in breast cancer
Bièche, I., & Lidereau, R. (1995) · Genes Chromosomes and Cancer · doi:10.1002/gcc.2870140402 · Cited by 303
Different angiogenic pathways characterize superficial and invasive bladder cancer.
O’Brien, T., Cranston, D., Fuggle, S., Bicknell, R., & Harris, A. L. (1995) · PubMed · Cited by 291
Molecular pathways of urothelial development and bladder tumorigenesis
Castillo-Martín, M., Domenech, J. M. D., Karni-Schmidt, O., Matos, T., & Cordon‐Cardo, C. (2010) · Urologic Oncology Seminars and Original Investigations · doi:10.1016/j.urolonc.2009.04.019 · Cited by 251
Self-citation
Oral Cancer
Sciubba, J. J. (2001) · American Journal of Clinical Dermatology · doi:10.2165/00128071-200102040-00005 · Cited by 248
Molecular subtypes of bladder cancer: Jekyll and Hyde or chalk and cheese?
Knowles, M. A. (2005) · Carcinogenesis · doi:10.1093/carcin/bgi310 · Cited by 250
Identification of gains and losses of DNA sequences in primary bladder cancer by comparative genomic hybridization
Kallioniemi, A. H., Kallioniemi, O., Citro, G., Sauter, G., DeVries, S., KERSCHMANN, R. L., Caroll, P. R., & Waldman, F. (1995) · Genes Chromosomes and Cancer · doi:10.1002/gcc.2870120309 · Cited by 230
Tumor Angiogenesis Correlates with Lymph Node Metastases in Invasive Bladder Cancer
Jaeger, T. M., Weidner, N., Chew, K., Moore, D. H., KERSCHMANN, R. L., Waldman, F. M., & Carroll, P. R. (1995) · The Journal of Urology · doi:10.1016/s0022-5347(01)67230-6 · Cited by 228
FGFR3 and P53 Characterize Alternative Genetic Pathways in the Pathogenesis of Urothelial Cell Carcinoma
van Rhijn, B. W. G., van der Kwast, T., Vis, A. N., Kirkels, W. J., Boevé, E. R., Jöbsis, A. C., & Zwarthoff, E. C. (2004) · Cancer Research · doi:10.1158/0008-5472.can-03-2421 · Cited by 227
Bladder cancers arise from distinct urothelial sub-populations
Batavia, J. V., Yamany, T., Molotkov, A., Dan, H., MANSUKHANI, M. M., Batourina, E., Schneider, K., Oyón, D., Dunlop, M., Wu, X., et al. (2014) · Nature Cell Biology · doi:10.1038/ncb3038 · Cited by 201
Self-citation
Carcinoma in Situ of the Bladder
Hudson, M. A., & Herr, H. W. (1995) · The Journal of Urology · doi:10.1016/s0022-5347(01)67650-x · Cited by 198
Molecular profiling of bladder cancer using cDNA microarrays: defining histogenesis and biological phenotypes.
Sänchez‐Carbayo, M., Socci, N. D., Charytonowicz, E., Lu, M.-L., Prystowsky, M. B., Childs, G. J., & Cordon‐Cardo, C. (2002) · PubMed · Cited by 197
Self-citation
Frequent FGFR3 mutations in urothelial papilloma
van Rhijn, B. W. G., Montironi, R., Zwarthoff, E. C., Jöbsis, A. C., & van der Kwast, T. (2002) · The Journal of Pathology · doi:10.1002/path.1202 · Cited by 189
Frequent Genetic Alterations in Simple Urothelial Hyperplasias of the Bladder in Patients with Papillary Urothelial Carcinoma
Hartmann, A., Moser, K., Kriegmair, M., Hofstetter, A., Hofstaedter, F., & Knuechel, R. (1999) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)65318-7 · Cited by 189
Gene Discovery in Bladder Cancer Progression using cDNA Microarrays
Sänchez‐Carbayo, M., Socci, N. D., Lozano, J. J., Li, W., Charytonowicz, E., Belbin, T. J., Prystowsky, M. B., Ortíz, Á. R., Childs, G. J., & Cordon‐Cardo, C. (2003) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)63679-6 · Cited by 181
Self-citation
Clonal and chronological genetic analysis of multifocal cancers of the bladder and upper urinary tract.
Takahashi, T., Habuchi, T., Kakehi, Y., Mitsumori, K., Akao, T., Terachi, T., & Yoshida, O. (1998) · PubMed · Cited by 176
Profiling Bladder Cancer Using Targeted Antibody Arrays
Sänchez‐Carbayo, M., Socci, N. D., Lozano, J. J., Haab, B. B., & Cordon‐Cardo, C. (2006) · American Journal Of Pathology · doi:10.2353/ajpath.2006.050601 · Cited by 167
Self-citation
Review of Chromosome Studies in Urological Tumors. II. Cytogenetics and Molecular Genetics of Bladder Cancer
Sandberg, A. A., & Berger, C. S. (1994) · The Journal of Urology · doi:10.1016/s0022-5347(17)35014-0 · Cited by 164
Role of Ha-ras activation in superficial papillary pathway of urothelial tumor formation
Zhang, Z. T., Pak, J., Huang, H. Y., Shapiro, E., Sun, T., Pellicer, À., & Wu, X. (2001) · Oncogene · doi:10.1038/sj.onc.1204315 · Cited by 159
Tumor Suppressor Role of KiSS-1 in Bladder Cancer
Sänchez‐Carbayo, M., Capodieci, P., & Cordon‐Cardo, C. (2003) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)63854-0 · Cited by 153
Self-citation
Patterns of Chromosomal Imbalances in Advanced Urinary Bladder Cancer Detected by Comparative Genomic Hybridization
Richter, J., Beffa, L., Wagner, U., Schraml, P., Gasser, T. C., Moch, H., Mihatsch, M. J., & Sauter, G. (1998) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)65750-1 · Cited by 150
Untitled work
(2002) · PubMed · Cited by 143
Self-citation
Chromosome 9 allelic losses and microsatellite alterations in human bladder tumors.
Orlow, I., LIANES, P., Lacombe, L., Dalbagni, G. M., Reuter, V. E., & Cordon‐Cardo, C. (1994) · PubMed · Cited by 140
Self-citation
Frequent epigenetic inactivation of RASSF1A in human bladder carcinoma.
Lee, M., Kim, H. Y., Byun, D.-S., Lee, S., Lee, C. H., Kim, J. I., Chang, S., & Chi, S. G. (2001) · PubMed · Cited by 134
Structure and Methylation-Based Silencing of a Gene (DBCCR1) within a Candidate Bladder Cancer Tumor Suppressor Region at 9q32–q33
Habuchi, T., Luscombe, M., Elder, P. A., & Knowles, M. A. (1998) · Genomics · doi:10.1006/geno.1997.5165 · Cited by 126
Molecular alterations associated with bladder cancer initiation and progression
Cordon‐Cardo, C. (2008) · Scandinavian Journal of Urology and Nephrology · doi:10.1080/03008880802291915 · Cited by 126
Self-citation
Partial allelotype of carcinoma in situ of the human bladder.
Rosin, M. P., Cairns, P., Epstein, J. I., Schoenberg, M., & Sidransky, D. (1995) · PubMed · Cited by 118
Hyperactivation of Ha-ras oncogene, but not Ink4a/Arf deficiency, triggers bladder tumorigenesis
Mo, L., Zheng, X., Huang, H.-Y., Shapiro, E., Lepor, H., Cordon‐Cardo, C., Sun, T., & Wu, X. (2007) · Journal of Clinical Investigation · doi:10.1172/jci30062 · Cited by 117
Self-citation
Microsatellite analysis of free tumor DNA in urine, serum, and plasma of patients: a minimally invasive method for the detection of bladder cancer.
Utting, M., Werner, W., Dahse, R., Schubert, J., & Junker, K. (2002) · PubMed · Cited by 114
Biological determinants of bladder cancer gene expression subtypes
Aine, M., Eriksson, P., Liedberg, F., Sjödahl, G., & Höglund, M. (2015) · Scientific Reports · doi:10.1038/srep10957 · Cited by 112
Genetic evidence in melanoma and bladder cancers that p16 and p53 function in separate pathways of tumor suppression.
Gruis, N. A., Weaver-Feldhaus, J., Liu, Q., Frye, C., Eeles, R. A., Orlow, I., Lacombe, L., Ponce-Castañeda, V., LIANES, P., & Latres, E. (1995) · Europe PMC (PubMed Central) · Cited by 113
Detection of chromosomal imbalances in transitional cell carcinoma of the bladder by comparative genomic hybridization.
Voorter, C. E. M., Joos, S., Bringuier, P., Vallinga, M., Poddighe, P. J., Schalken, J. A., du Manoir, S., Ramaekers, F. C. S., Lichter, P., & Hopman, A. H. N. (1995) · Europe PMC (PubMed Central) · Cited by 112
Durability of the Tumor-Free Response for Intravesical Bacillus Calmette-Guerin Therapy
Nadler, R. B., Catàlona, W. J., Hudson, M. A., & Ratliff, T. L. (1994) · The Journal of Urology · doi:10.1016/s0022-5347(17)32741-6 · Cited by 111
Chromosomal imbalances in noninvasive papillary bladder neoplasms (pTa).
Zhao, J., Richter, J., Wagner, U., Roth, B., Schraml, P., Zellweger, T., Ackermann, D., Schmid, U., Moch, H., Mihatsch, M. J., et al. (1999) · PubMed · Cited by 110
Molecular genetic alterations in the laser‐capture–microdissected stroma adjacent to bladder carcinoma
Paterson, R. F., Ulbright, T. M., MacLennan, G. T., Zhang, S., Pan, C.-X., Sweeney, C. J., Moore, C. R., Foster, R. S., Koch, M. O., Eble, J. N., et al. (2003) · Cancer · doi:10.1002/cncr.11747 · Cited by 106
Novel suppressor loci on chromosome 14q in primary bladder cancer.
Chang, W. Y., Cairns, P., Schoenberg, M., Polascik, T. J., & Sidransky, D. (1995) · PubMed · Cited by 105
Genetic alterations in primary bladder cancers and their metastases.
Hovey, R. M., Chu, L. W., Balázs, M., DeVries, S., Moore, D. H., Sauter, G., Carroll, P. R., & Waldman, F. M. (1998) · PubMed · Cited by 103
Four tumor suppressor loci on chromosome 9q in bladder cancer: evidence for two novel candidate regions at 9q22.3 and 9q31
Simoneau, M., Aboulkassim, T., LaRue, H., Rousseau, F., & Fradet, Y. (1999) · Oncogene · doi:10.1038/sj.onc.1202277 · Cited by 102
Analysis of the copy number profiles of several tumor samples from the same patient reveals the successive steps in tumorigenesis
Letouzé, É., Allory, Y., Bollet, M. A., Radvanyi, F., & Guyon, F. (2010) · Genome biology · doi:10.1186/gb-2010-11-7-r76 · Cited by 101
Bladder cancer in Africa: Update
ELMAWLA, N. (2001) · Seminars in Oncology · doi:10.1016/s0093-7754(01)90089-2 · Cited by 101
Poster 7: A Genetic Progression Model for Head and Neck Cancer: Implications for Field Cancerization
Califano, J. A., Clayman, G. L., Sidransky, D., Koch, W. M., Piantadosi, S., van der Riet, P., Nawroz, H., Westra, W. H., & Corio, R. L. (1996) · Otolaryngology · doi:10.1016/s0194-5998(96)80631-0 · Cited by 100
The imprinted H19 gene as a tumor marker in bladder carcinoma
Ariel, I. M., Lustig, O., Schneider, T., Pizov, G., Sappir, M., de-Groot, N., & Hochberg, A. (1995) · Urology · doi:10.1016/0090-4295(95)80030-1 · Cited by 97
Molecular Detection of Noninvasive and Invasive Bladder Tumor Tissues and Exfoliated Cells by Aberrant Promoter Methylation of Laminin-5 Encoding Genes
Sathyanarayana, U. G., Maruyama, R., Padar, A., Suzuki, M., Bondaruk, J. E., Sagalowsky, A. I., Minna, J. D., Frenkel, E. P., Grossman, H. B., Czerniak, B. A., et al. (2004) · Cancer Research · doi:10.1158/0008-5472.can-03-0701 · Cited by 93
Overexpression of epidermal growth factor receptor in urothelium elicits urothelial hyperplasia and promotes bladder tumor growth.
Cheng, J. Q., Huang, H., Zhang, Z.-T., Shapiro, E., Pellicer, À., Sun, T., & Wu, X. (2002) · PubMed · Cited by 92
Prognostic value of amplification of c-erb-B2 in bladder carcinoma.
Lönn, U., Lönn, S., Friberg, S. G., Nilsson, B., Silfverswärd, C., & Stenkvist, B. (1995) · PubMed · Cited by 92
DISTINCT MICROSATELLITE ALTERATIONS IN UPPER URINARY TRACT TUMORS AND SUBSEQUENT BLADDER TUMORS
Takahashi, T., Kakehi, Y., Mitsumori, K., Akao, T., Terachi, T., Kato, T., Ogawa, O., & Habuchi, T. (2001) · The Journal of Urology · doi:10.1097/00005392-200102000-00092 · Cited by 89
Differential expression of hMLH1 and hMSH2 is related to bladder cancer grade, stage and prognosis but not microsatellite instability
Catto, J. W. F., Xinarianos, G., Burton, J. L., Meuth, M., & Hamdy, F. C. (2003) · International Journal of Cancer · doi:10.1002/ijc.11109 · Cited by 87
Translation initiation factor eIF-4G is immunogenic, overexpressed, and amplified in patients with squamous cell lung carcinoma
Bauer, C., Diesinger, I., Brass, N., Steinhart, H., Iro, H., & Meese, E. U. (2001) · Cancer · doi:10.1002/1097-0142(20010815)92:4 · Cited by 70
Combined microsatellite and FGFR3 mutation analysis enables a highly sensitive detection of urothelial cell carcinoma in voided urine.
van Rhijn, B. W. G., Lurkin, I., Chopin, D. K., Kirkels, W. J., Thiery, J. P., van der Kwast, T., Radvanyi, F., & Zwarthoff, E. C. (2003) · PubMed · Cited by 86
Timing somatic events in the evolution of cancer
Jolly, C., & Loo, P. V. (2018) · Genome biology · doi:10.1186/s13059-018-1476-3 · Cited by 86
Deficiency of pRb Family Proteins and p53 in Invasive Urothelial Tumorigenesis
He, F., Mo, L., Zheng, X., Hu, C., Lepor, H., Lee, E. Y.-H. P., Sun, T., & Wu, X. (2009) · Cancer Research · doi:10.1158/0008-5472.can-09-2158 · Cited by 83
Genetic and Molecular Markers of Urothelial Premalignancy and Malignancy
Cordon‐Cardo, C., Côté, R. J., & Sauter, G. (2000) · Scandinavian Journal of Urology and Nephrology · doi:10.1080/003655900750169338 · Cited by 78
Self-citation
Genetic and epigenetic alterations in normal bladder epithelium in patients with metachronous bladder cancer.
Muto, S., Horie, S., Takahashi, S., Tomita, K., & Kitamura, T. (2000) · PubMed · Cited by 80
Persistent uroplakin expression in advanced urothelial carcinomas: implications in urothelial tumor progression and clinical outcome
Huang, H.-Y., Shariat, S. F., Sun, T., Lepor, H., Shapiro, E., Hsieh, J., Ashfaq, R., Lotan, Y., & Wu, X. (2007) · Human Pathology · doi:10.1016/j.humpath.2007.04.003 · Cited by 78
Chromosome 9 deletions and recurrence of superficial bladder cancer: identification of four regions of prognostic interest
Simoneau, M., LaRue, H., Aboulkassim, T., Meyer, F., Moore, L., & Fradet, Y. (2000) · Oncogene · doi:10.1038/sj.onc.1204022 · Cited by 78
Structure, function, and chromosome mapping of thegrowth-suppressing human homologue of the murine gas1 gene.
Sal, G. D., Collavin, L., Ruaro, M. E., Edomi, P., Saccone, S., Valle, G., & Schneider, C. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.5.1848 · Cited by 78
Molecular markers in bladder cancer
Shariat, S. F., Karam, J. A., & Lerner, S. P. (2008) · Current Opinion in Urology · doi:10.1097/mou.0b013e3282f1c5c1 · Cited by 77
Assessing the Use of p16INK4a Promoter Gene Methylation in Serum for Detection of Bladder Cancer
Valenzuela, M. (2002) · European Urology · doi:10.1016/s0302-2838(02)00468-2 · Cited by 77
Predicting chemoresistance in human malignant glioma cells: The role of molecular genetic analyses
Weller, M., Rieger, J., Grimmel, C., Meir, E. G. V., de Tribolet, N., Krajewski, S., Reed, J. C., von Deimling, A., & DICHGANS, J. (1998) · International Journal of Cancer · doi:10.1002/(sici)1097-0215(19981218)79:6 · Cited by 177
Uncovering the clinical utility of miR-143, miR-145 and miR-224 for predicting the survival of bladder cancer patients following treatment
Avgeris, M., Mavridis, K., Tokas, T., STRAVODIMOS, K. G., Fragoulis, E. G., & Scorilas, A. (2015) · Carcinogenesis · doi:10.1093/carcin/bgv024 · Cited by 74
Fibroblast growth factor receptor-3 in urothelial tumorigenesis
Iyer, G., & Milowsky, M. I. (2012) · Urologic Oncology Seminars and Original Investigations · doi:10.1016/j.urolonc.2011.12.001 · Cited by 72
A Novel Candidate Tumour Suppressor Locus at 9q32–33 in Bladder Cancer: Localization of the Candidate Region Within a Single 840 kb YAC
Habuchi, T., Yoshida, O., & Knowles, M. A. (1997) · Human Molecular Genetics · doi:10.1093/hmg/6.6.913 · Cited by 72
Chromosome 3 allelic losses and microsatellite alterations in transitional cell carcinoma of the urinary bladder.
Li, M., Zhang, Z., Reuter, V. E., & Cordon‐Cardo, C. (1996) · Europe PMC (PubMed Central) · Cited by 72
Self-citation
Loss of heterozygosity on chromosome 18q is associated with muscle-invasive transitional cell carcinoma of the bladder
BREWSTER, S. F., Gingell, J. C., Browne, S. J., & Brown, K. W. (1994) · British Journal of Cancer · doi:10.1038/bjc.1994.376 · Cited by 72
Y chromosome loss detected by FISH in bladder cancer
Sauter, G., Moch, H., Wagner, U., Novotná, H., Gasser, T. C., Mattarelli, G., Mihatsch, M. J., & Waldman, F. (1995) · Cancer Genetics and Cytogenetics · doi:10.1016/0165-4608(95)00030-s · Cited by 71
Frequent loss of chromosome 3p and hypermethylation of RASSF1A in cholangiocarcinoma
Wong, N., Li, L., Tsang, K. S., Lai, P. B. S., To, K., & Johnson, P. J. (2002) · Journal of Hepatology · doi:10.1016/s0168-8278(02)00269-6 · Cited by 68
Detection of Genetic Alterations in Bladder Tumors by Comparative Genomic Hybridization and Cytogenetic Analysis
Koo, S. H., Kwon, K. C., Ihm, C. H., Jeon, Y. M., Park, J. W., & Sul, C.-K. (1999) · Cancer Genetics and Cytogenetics · doi:10.1016/s0165-4608(98)00193-9 · Cited by 67
Immunohistochemical biomarkers for bladder cancer prognosis
Matsushita, K., Cha, E. K., Matsumoto, K., Baba, S., Chromecki, T. F., Fajković, H., Sun, M., Karakiewicz, P. I., Scherr, D. S., & Shariat, S. F. (2011) · International Journal of Urology · doi:10.1111/j.1442-2042.2011.02809.x · Cited by 66
Vysis®UroVysion for the detection of urothelial carcinoma
Halling, K. C. (2003) · Expert Review of Molecular Diagnostics · doi:10.1586/14737159.3.4.507 · Cited by 65
Loss of blood group A antigen expression in bladder cancer caused by allelic loss and/or methylation of the ABO gene
Chihara, Y., Sugano, K., Kobayashi, A., Kanai, Y., Yamamoto, H., Nakazono, M., Fujimoto, H., Kakizoe, T., Fujimoto, K., Hirohashi, S., et al. (2005) · Laboratory Investigation · doi:10.1038/labinvest.3700268 · Cited by 65
Molecular Alterations Associated With Bladder Cancer Progression
Sänchez‐Carbayo, M., & Cordon‐Cardo, C. (2007) · Seminars in Oncology · doi:10.1053/j.seminoncol.2006.12.013 · Cited by 65
Self-citation
Metformin represses bladder cancer progression by inhibiting stem cell repopulation via COX2/PGE2/STAT3 axis
Liu, Q., Yuan, W., Tong, D., Liu, G., Lan, W., Zhang, D., Xiao, H., Zhang, Y., Huang, Z., Yang, J., et al. (2016) · Oncotarget · doi:10.18632/oncotarget.8595 · Cited by 65
Chromosome‐9 loss detected by fluorescence in situ hybridization in bladder cancer
Sauter, G., Moch, H., Carroll, P. R., Kerschmann, R., Mihatsch, M. J., & Waldman, F. M. (1995) · International Journal of Cancer · doi:10.1002/ijc.2910640205 · Cited by 60
Negative regulation of G1/S transition by the candidate bladder tumour suppressor gene DBCCR1
Nishiyama, H., Gill, J. H., Pitt, E., Kennedy, W., & Knowles, M. A. (2001) · Oncogene · doi:10.1038/sj.onc.1204432 · Cited by 59
Carcinoma in Situ of the Bladder
Hudson, M. A., & Herr, H. W. (1995) · The Journal of Urology · doi:10.1097/00005392-199503000-00002 · Cited by 57
Biomolecular Predictors of Urothelial Cancer Behavior and Treatment Outcomes
Rink, M., Cha, E. K., Green, D., Hansen, J., Robinson, B. D., Lotan, Y., Sagalowsky, A. I., Chun, F. K. ‐., Karakiewicz, P. I., Fisch, M., et al. (2012) · Current Urology Reports · doi:10.1007/s11934-012-0237-1 · Cited by 56
Genetic studies and molecular markers of bladder cancer
Cordon‐Cardo, C., Sheinfeld, J., & Dalbagni, G. M. (1997) · Seminars in Surgical Oncology · doi:10.1002/(sici)1098-2388(199709/10)13:5 · Cited by 55
Developmentally Imprinted Genes as Markers for Bladder Tumor Progression
Cooper, M. J., Fischer, M., Komitowski, D. D., Shevelev, A., Schulze, E., Ariel, I., Tykocinski, M. L., Miron, S., Ilan, J., GROOT, N. D., et al. (1996) · The Journal of Urology · doi:10.1016/s0022-5347(01)66120-2 · Cited by 53
Telomerase activity in relation to p53 status and clinico-pathological parameters in breast cancer
Roos, G., Nilsson, P., Cajander, S. B., Nielsen, N. H., Arnerlöv, C., & Landberg, G. (1998) · International Journal of Cancer · doi:10.1002/(sici)1097-0215(19980821)79:4 · Cited by 60
Tumor suppressor role for myopodin in bladder cancer: loss of nuclear expression of myopodin is cell-cycle dependent and predicts clinical outcome
Sänchez‐Carbayo, M., Schwarz, K., Charytonowicz, E., Cordon‐Cardo, C., & Mundel, P. H. (2003) · Oncogene · doi:10.1038/sj.onc.1206616 · Cited by 51
Self-citation
Cyclin-Dependent Kinase Inhibitors and Human Cancer
Kamb, A. (1998) · Current topics in microbiology and immunology · doi:10.1007/978-3-642-71941-7_7 · Cited by 50
Non‐invasive molecular detection of bladder cancer recurrence
Amira, N., Mourah, S., Rozet, F., Teillac, P., Fiet, J., Aubin, P., Cortesse, A., Desgrandchamps, F., Duc, A. L., Cussenot, O., et al. (2002) · International Journal of Cancer · doi:10.1002/ijc.10561 · Cited by 50
Interphase Cytogenetic Analysis of Solid Tumors by Non-Isotopic DNA in situ Hybridization
Alers, J. C., & van Dekken, H. (1996) · Progress in Histochemistry and Cytochemistry · doi:10.1016/s0079-6336(96)80017-9 · Cited by 48
The sensitivity of fluorescent‐light cystoscopy for the detection of carcinoma in situ (CIS) of the bladder: a meta‐analysis with comments on gold standard
Isfoss, B. L. (2011) · British Journal of Urology · doi:10.1111/j.1464-410x.2011.10485.x · Cited by 48
Hedgehog Signaling Regulates Bladder Cancer Growth and Tumorigenicity
Fei, D. L., Sánchez-Mejías, A., Wang, Z., Flaveny, C. A., Long, J., Singh, S., Rodríguez‐Blanco, J., Tokhunts, R. A., Giambelli, C., Briegel, K. J., et al. (2012) · Cancer Research · doi:10.1158/0008-5472.can-11-4123 · Cited by 47
5α-reductase and 17β-hydroxysteroid dehydrogenase expression in epithelial cells from hyperplastic and malignant human prostate
Délos, S., Carsol, J.-L., Fina, F., Raynaud, J., & Martin, P. (1998) · International Journal of Cancer · doi:10.1002/(sici)1097-0215(19980316)75:6 · Cited by 21
Self-citation
Multistep laryngeal carcinogenesis helps our understanding of the field cancerisation phenomenon: a review
Almadori, G., Bussu, F., Cadoni, G., Galli, J., Rigante, M., Artuso, A., & Maurizi, M. (2004) · European Journal of Cancer · doi:10.1016/j.ejca.2004.04.023 · Cited by 45
Genetic aspects of prostate cancer
Latil, A., & Lidereau, R. (1998) · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin · doi:10.1007/s004280050183 · Cited by 43
Allelic Loss of the Active X Chromosome During Bladder Carcinogenesis
Liang Cheng, C., MacLennan, G. T., Pan, C.-X., Jones, T. D., Moore, C. R., Zhang, S., Gu, J., Patel, N., Kao, C. H., & Gardner, T. A. (2004) · Archives of Pathology & Laboratory Medicine · doi:10.5858/2004-128-187-alotax · Cited by 43
CHK1 frameshift mutations in genetically unstable colorectal and endometrial cancers
Bertoni, F., Codegoni, A. M., Furlan, D., Tibiletti, M. G., Capella, C., & Broggini, M. (1999) · Genes Chromosomes and Cancer · doi:10.1002/(sici)1098-2264(199910)26:2 · Cited by 132
Classification of bladder cancer by microarray expression profiling: towards a general clinical use of microarrays in cancer diagnostics
Dyrskjøt, L. (2003) · Expert Review of Molecular Diagnostics · doi:10.1586/14737159.3.5.635 · Cited by 40
Molecular targeting in the treatment of either advanced or metastatic bladder cancer or both according to the signalling pathways
Wallerand, H., Reiter, R. E., & Ravaud, A. (2008) · Current Opinion in Urology · doi:10.1097/mou.0b013e3283097889 · Cited by 39
‘Superficial’ bladder cancer – time to uncouple pT1 tumours from pTa tumours
Bryan, R. T., & Wallace, D. M. A. (2002) · British Journal of Urology · doi:10.1046/j.1464-410x.2002.03053.x · Cited by 40

Authors: Dalbagni, G., Presti, J., Fair, W. R., Reuter, V., & Cordon-Cardo, C.
Affiliations: Memorial Sloan Kettering Cancer Center (US)
ORCID: Dalbagni, G.
Presti, J.
Reuter, V.
Venue: The Lancet
Publisher: Elsevier BV
Published: 1993-08
Volume: 342
Issue: 8869
Pages: 469-471
ISSN: 0099-5355 (ISSN-L)
0140-6736
DOI: 10.1016/0140-6736(93)91595-d
OpenAlex: W2039609330
Cited by: 238
References: 9
Citations by year: 2025: 1 · 2024: 4 · 2020: 2 · 2019: 1 · 2018: 3 · 2017: 2 · 2016: 3 · 2015: 6 · 2014: 4 · 2013: 6 · 2012: 7
FWCI: 18.33
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: The Lancet (publishedVersion)
PubMed (publishedVersion)
Funders: National Cancer Institute (NCI CA-47538)
Topics: Health Sciences › Medicine › Surgery › Bladder and Urothelial Cancer Treatments
Health Sciences › Medicine › Surgery › Urinary and Genital Oncology Studies
Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Cancer Genomics and Diagnostics
Keywords: bladder cancer, loss of heterozygosity, tumor suppressor, 9q deletion, muscle-invasive bladder cancer, tumor progression, chromosomal abnormalities, 3p deletion, 5q deletion, 17p deletion, clinical outcomes
MeSH terms: Alleles, Urinary Bladder Neoplasms, Chromosome Deletion, Chromosomes, Human, Pair 13, Chromosomes, Human, Pair 17, Chromosomes, Human, Pair 3, Chromosomes, Human, Pair 5, Chromosomes, Human, Pair 9, Genotype, Heterozygote, Humans, Neoplasm Invasiveness, Neoplasm Staging, Prognosis, Genes, Tumor Suppressor

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Genetic alterations in bladder cancer

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks