The DOI matches its Crossref record; 135 of the 135 references it cites were found in a registry or an index.
Metal carcinogenesis: Mechanistic implications
Open accessAbstract
Cancer epidemiology has identified several metal compounds as human carcinogens. Recent evidence suggests that carcinogenic metals induce genotoxicity in a multiplicity of ways, either alone or by enhancing the effects of other agents. This review summarizes current information on the genotoxicity of arsenic, chromium, nickel, beryllium and cadmium compounds and their possible roles in carcinogenesis. Each of these metals is distinct in its primary modes of action; yet there are several mechanisms induced by more than one metal, including: the induction of cellular immunity and oxidative stress, the inhibition of DNA metabolism and repair and the formation of DNA- and/or protein-crosslinks.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
p53 Mutations in Human Cancers
Hollstein, M., Sidransky, D., Vogelstein, B., & Harris, C. C. (1991) · Science · doi:10.1126/science.1905840 · Cited by 8,018
ras oncogenes in human cancer: a review.
Bos, J. L. (1989) · PubMed · Cited by 5,061
Production of large amounts of hydrogen peroxide by human tumor cells.
Szatrowski, T. P., & Nathan, C. (1991) · PubMed · Cited by 2,526
Weinberg, R. A. (1991) · Science · doi:10.1126/science.1659741 · Cited by 1,756
(1991) · PubMed · Cited by 1,305
Keyse, S. M., & Tyrrell, R. M. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.1.99 · Cited by 1,264
Potential Metal-Binding Domains in Nucleic Acid Binding Proteins
Berg, J. M. (1986) · Science · doi:10.1126/science.2421409 · Cited by 1,061
Abnormal Proteins Serve as Eukaryotic Stress Signals and Trigger the Activation of Heat Shock Genes
Ananthan, J., Goldberg, A. L., & Voellmy, R. (1986) · Science · doi:10.1126/science.3083508 · Cited by 898
Waalkes, M. P. (2003) · Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis · doi:10.1016/j.mrfmmm.2003.07.011 · Cited by 889
The role of 8-hydroxyguanine in carcinogenesis
Floyd, R. A. (1990) · Carcinogenesis · doi:10.1093/carcin/11.9.1447 · Cited by 718
Cited by
Jing, Y., Dai, J., Chalmers-Redman, R. M. E., Tatton, W. G., & Waxman, S. (1999) · Blood · doi:10.1182/blood.v94.6.2102 · Cited by 543
Estrogen-Like Activity of Metals in Mcf-7 Breast Cancer Cells
Martin, M. B., Reiter, R., Pham, T., Avellanet, Y. R., Camara, J., Lahm, M., Pentecost, E., Pratap, K., Gilmore, B. A., Divekar, S., et al. (2003) · Endocrinology · doi:10.1210/en.2002-221054 · Cited by 409
Threshold mechanisms and site specificity in chromium(VI) carcinogenesis
De Flora, S. (2000) · Carcinogenesis · doi:10.1093/carcin/21.4.533 · Cited by 339
Arsenic carcinogenesis in the skin
Yu, H.-S., Liao, W.-T., & Chai, C.-Y. (2006) · Journal of Biomedical Science · doi:10.1007/s11373-006-9092-8 · Cited by 318
The solubility of Cr(III) and Cr(VI) compounds in soil and their availability to plants
MANDIWANA, K., PANICHEV, N., KATAEVA, M., & SIEBERT, S. (2007) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2007.01.049 · Cited by 39
Metadata
- Authors
- Snow, E. T.
- Venue
- Pharmacology & Therapeutics
- Publisher
- Elsevier BV
- Published
- 1992
- Volume
- 53
- Issue
- 1
- Pages
- 31-65
- ISSN
- 0163-7258 (ISSN-L)
- OpenAlex
- W2099604330
- Cited by
- 353
- References
- 135
- FWCI
- 3.26
- Type
- journal article
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Metal carcinogenesis: Mechanistic implications. https://app.cochat.ai/papers/10.1016/0163-7258(92)90043-y
- The paper
- Snow, E. T. (1992). Metal carcinogenesis: Mechanistic implications. Pharmacology & Therapeutics. https://doi.org/10.1016/0163-7258(92)90043-y
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
